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Entry version 53 (02 Dec 2020)
Sequence version 3 (11 Dec 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

CDH23

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDH23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3071 – 3094HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_502381545624 – 3358Sequence analysisAdd BLAST3335

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000023411, Expressed in liver and 15 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6XRV0, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 132CadherinInterPro annotationAdd BLAST91
Domaini133 – 240CadherinInterPro annotationAdd BLAST108
Domaini241 – 352CadherinInterPro annotationAdd BLAST112
Domaini353 – 464CadherinInterPro annotationAdd BLAST112
Domaini465 – 565CadherinInterPro annotationAdd BLAST101
Domaini566 – 675CadherinInterPro annotationAdd BLAST110
Domaini676 – 788CadherinInterPro annotationAdd BLAST113
Domaini783 – 894CadherinInterPro annotationAdd BLAST112
Domaini895 – 999CadherinInterPro annotationAdd BLAST105
Domaini1000 – 1106CadherinInterPro annotationAdd BLAST107
Domaini1107 – 1212CadherinInterPro annotationAdd BLAST106
Domaini1214 – 1317CadherinInterPro annotationAdd BLAST104
Domaini1318 – 1422CadherinInterPro annotationAdd BLAST105
Domaini1424 – 1531CadherinInterPro annotationAdd BLAST108
Domaini1533 – 1638CadherinInterPro annotationAdd BLAST106
Domaini1639 – 1748CadherinInterPro annotationAdd BLAST110
Domaini1763 – 1855CadherinInterPro annotationAdd BLAST93
Domaini1856 – 1963CadherinInterPro annotationAdd BLAST108
Domaini1964 – 2073CadherinInterPro annotationAdd BLAST110
Domaini2074 – 2178CadherinInterPro annotationAdd BLAST105
Domaini2179 – 2297CadherinInterPro annotationAdd BLAST119
Domaini2301 – 2406CadherinInterPro annotationAdd BLAST106
Domaini2407 – 2513CadherinInterPro annotationAdd BLAST107
Domaini2514 – 2615CadherinInterPro annotationAdd BLAST102
Domaini2618 – 2726CadherinInterPro annotationAdd BLAST109
Domaini2733 – 2850CadherinInterPro annotationAdd BLAST118
Domaini2851 – 2979CadherinInterPro annotationAdd BLAST129

Keywords - Domaini

RepeatARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155245

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23

The PANTHER Classification System

More...
PANTHERi
PTHR24025:SF18, PTHR24025:SF18, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00028, Cadherin, 24 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205, CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112, CA, 26 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313, SSF49313, 27 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

F6XRV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRCHVATGCH VVWLFVLISG SWGQVNRLPF FTNHFFDTYL LISEDTPVGS
60 70 80 90 100
SVTQLLARDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE
110 120 130 140 150
FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPEVGAGNTP
160 170 180 190 200
VGTPIFIVNA TDPDLGAGGS VLYSFQPPSL FFAIDSARGI VTVIRELDYE
210 220 230 240 250
TTQAYQLTVN ATDQDKTRPL STLANLAIII TDIQDMDPIF INLPYSTNIY
260 270 280 290 300
EHSPPGTTVR IITAIDQDKG RPRGIGYTIV SGNTNSIFAL DYISGALTLN
310 320 330 340 350
GLLDRENPLY SHGFILTVKG TELNDDRTPS NATVTTTFNI LVIDINDNAP
360 370 380 390 400
EFNSSEYSVA ITELAQVGFA LPLFIQVVDK DENLGLNSMF EVYLVGNNSH
410 420 430 440 450
HFIISPTSVQ GKADIRIRVA IPLDFETVDR YDFDLFANES VPDHVGYAKV
460 470 480 490 500
KITLINENDN RPIFSQPLYN ISLYENVTVG TSVLTVLATD NDVGTFGEVN
510 520 530 540 550
YFFSDDPDRF SLDKDTGLIM LIARLDYELI QRFTLTVIAR DGGGEETTGR
560 570 580 590 600
VRINVLDVND NAPTFQKDAY VGALRENEPS VTQLVRLRAT DEDSPPNNQI
610 620 630 640 650
TYSIVSASAF GSYFDISVYE GYGVISVSRP LDYEQIPNGL IYLMVMAKDA
660 670 680 690 700
GNPPLNSTVP VTIEVFDEND NPPTFSKPAY FVSVVENIMA GATVLFLNAT
710 720 730 740 750
DLDRSREYGQ ESIIYSLEGS SQFRINARSG EITTTSLLDR ETKSEYILIV
760 770 780 790 800
RAVDGGVGHN QKTGIATVNI TILDINDNHP AWKDAPYYIN LVEMTPPDSD
810 820 830 840 850
VTTVVAVDPD LGENGTLVYS IQPPNKFYSL NSSTGKIRTT HVMLDRENPD
860 870 880 890 900
PHEAELMRKI VVSVTDCGRP PLRATSSATV FVNLLDLNDN DPTFQNLPFV
910 920 930 940 950
AEVLEGTPAG VSIYQVVAID LDEGLNGLVT YRMQVGMPRM DFLINSSSGV
960 970 980 990 1000
VVTTTELDRE RIAEYQLRVV ASDAGTPTKS STSTLTIRVL DVNDETPTFF
1010 1020 1030 1040 1050
PAVYNVSVSE DVPREFRVVW LNCTDNDVGL NAELSYFITG GNVDGKFSVG
1060 1070 1080 1090 1100
YRDAVVRTVV SLDRETTASY TLVLEAIDNG PVGKRRTGTA TVFITVLDVN
1110 1120 1130 1140 1150
DNRPIFLQSS YEASVPEDIP EGHSIVQLKA TDADEGEFGR VWYRILQGNH
1160 1170 1180 1190 1200
GNNFRIHVSS GLLMRGPRSL DRERNSSHVL IVEAYNHDLG PMRSSVRVIV
1210 1220 1230 1240 1250
YVEDVNDEAP VFTQQQYSRL GLRETAGIGT SVIVVRATDR DTGDGGLVNY
1260 1270 1280 1290 1300
RILSGAEGKF EVDESTGLII TVEYLDYETK TSYLMNVSAT DQAPPFNQGF
1310 1320 1330 1340 1350
CSVYVTLLNE LDEAVQFSNA SYEAAILENL ALGTEIVRVQ AYSIDNLNQI
1360 1370 1380 1390 1400
TYRFDAYTSA QAKALFKIDA ITGVITVKGL VDREKGDFYT LTVVADDGGP
1410 1420 1430 1440 1450
KVDSTVKVYI TVLDENDNSP RFDFTSDSAV SVPEDCPVGQ RMATVKARDP
1460 1470 1480 1490 1500
DAGSNGQVVF SLASGNIAGA FEIITTNDST GEVFVARPLD REELDHYILK
1510 1520 1530 1540 1550
VVASDRGTPP RKKDHILQVT ILDVNDNPPV IESPFGYNVS VNENVGGGTA
1560 1570 1580 1590 1600
VVQVRASDRD IGINSILSYY ITKGNEDMTF RMDRISGEIA TRPAPPDRER
1610 1620 1630 1640 1650
QSFYHLVVTV EDEGTPTLSA TTHVYVTIVD ENDNTPVFQQ PHYEILLDEG
1660 1670 1680 1690 1700
PDTINTSLIT IQALDLDEGP NGTVAYAIVT GNIINTFRIN SHSGVISAAK
1710 1720 1730 1740 1750
ELDYEISQGR YTLIVTATDQ CPILSRRLTS TATVLVNVND INDNVPTFPR
1760 1770 1780 1790 1800
DYEGPFDVTE GQPGPRVWTF LAHDRDSGPN GQVEYGILDG DPLGEFVISP
1810 1820 1830 1840 1850
VEGVLRVRKD VELDRETIAF YNLTICARDR GMPPLSSTML VGIRVLDIND
1860 1870 1880 1890 1900
NDPVLLNLPM NITISENSPI SSFVAHVLAS DADSGCNALL TFNITAGNRE
1910 1920 1930 1940 1950
RAFSINATTG IVTVNRPLDR ERIPDYKLTI SVKDNPDNPR IARRDFDLLL
1960 1970 1980 1990 2000
IFLVDENDNQ PLFTESTYQA EVMENSPAGT PLTVLNGPIL ALDADLDVYA
2010 2020 2030 2040 2050
VVTYQLLGSQ SGLFDINNST GMVTVRSGVI IDREAFSPPV LELLLLAEDI
2060 2070 2080 2090 2100
GLLNSTADLL VTILDDNDNF PTFSPATLTV HLLENCPPGF SVLQVTATDE
2110 2120 2130 2140 2150
DSGLNGELIY RIEAGAQDRF LIHPVTGVIR VGNATIDREE QESYRLTVVA
2160 2170 2180 2190 2200
TDRGTVPLSG TAIITILIDD INDSRPEFLN PIQTVSVLES VEPGTVIANV
2210 2220 2230 2240 2250
TAIDRDLDPK LEYRIIGIVA KDDTDRLVPD QEDAFAVNIN TGSVMVKSPL
2260 2270 2280 2290 2300
NRELVATYEV TLSVIDNASD LPERSVSVPN AKLTVNILDV NDNTPQFKPF
2310 2320 2330 2340 2350
GITYYTERIL EGATLGTTLI AVAAVDPDKG LNGLITYTLL DLMPPGYVQL
2360 2370 2380 2390 2400
EDSSAGKVIA NRTVDYEEVH WLNFTVRASD NGSPPRAAEI PVYLEIVDIN
2410 2420 2430 2440 2450
DNNPIFDQPS YQEAVFEDVP VGTVILTVTA TDADSGNFAL VEYSLGDGEG
2460 2470 2480 2490 2500
KFAINPVTGD IYVLSSLDRE KKDHYILTAL AKDNPGDAAS NRRENSVQVV
2510 2520 2530 2540 2550
IQVLDINDCR PQFSKPQFST SVYENEPAGT SVITMMATDQ DEGSNGELAY
2560 2570 2580 2590 2600
SLEGPGVEAF YVDIDSGLVT TKRPLQSYER FNLTVVATDG GQPPLWGTTM
2610 2620 2630 2640 2650
LLVEVIDVND NRPIFVRPPN GTILHIREET PLRSNVYEVY ATDKDEGLNG
2660 2670 2680 2690 2700
AVRYSFLKTA GNRDWEYFTI DPISGLIQTA QRLDREKQAV YSLILVASDL
2710 2720 2730 2740 2750
GQPVPYETMQ PLQVALEDID DNEPLFVRPP KGSPQYQLLT VPEHSPHGTL
2760 2770 2780 2790 2800
VGNVTGAVDA DEGPNAIVYY FIAAGNEEKN FHLHPDGRLL VLRDLDRERE
2810 2820 2830 2840 2850
AVFSFIVKAS SNSSWTPPRG PSPALDLVTD LTLQEVRVVL EDINDQPPRF
2860 2870 2880 2890 2900
TKAEYTAGVA TDAKVGSELI QVLALDADIG NNSLVFYSIL AIHYFRALAN
2910 2920 2930 2940 2950
DSEDMGQVFT MGSMDGILRT FDLFMAYSPG YFVVDIVARD LAGHNDTAVI
2960 2970 2980 2990 3000
GIYILRDDQR VKIVINEIPD RVRDFEEEFI RLLSNITGAI VNTDDVQFHV
3010 3020 3030 3040 3050
DKKGRVNFAQ TELLIHVVNR ETNRILDVDR VIQMIDENKE QLRNLFRNYN
3060 3070 3080 3090 3100
VLDVQPAISV RLPDDMSALQ MAIIVLAILL FLAAMLFILM NWYYRTIHKR
3110 3120 3130 3140 3150
KLKAIVAGSA GNRGFIDIMD MPNTNKYSFD GANPVWLDPF CRNLELAAQA
3160 3170 3180 3190 3200
EHEDDLPENL SEIADLWNSP TRTHGTFGRE PAAVKPDDDR YLRAAIQEYD
3210 3220 3230 3240 3250
NIAKLGQIIR EGPIKGSLLK VVLEDYLRLK KLFAQRMVQK AASCHSSISE
3260 3270 3280 3290 3300
LIPTELEEEP GECSPGQGSL RFCHKPPTEL KGPDGIHMVH GSTGTLLATD
3310 3320 3330 3340 3350
LNSLPEDDQK GLGRSLETLT AAEASAFERN ARTESAKSTP LHKLRDVIME

SPLEITEL
Length:3,358
Mass (Da):369,646
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB0C8F3E2BC186BE9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XLQ0F6XLQ0_HORSE
Uncharacterized protein
CDH23
3,353Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6XLL6F6XLL6_HORSE
Uncharacterized protein
CDH23
1,079Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GRP0A0A3Q2GRP0_HORSE
Uncharacterized protein
CDH23
1,380Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HCH9A0A3Q2HCH9_HORSE
Uncharacterized protein
CDH23
1,048Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HD56A0A3Q2HD56_HORSE
Uncharacterized protein
CDH23
525Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000026167; ENSECAP00000021808; ENSECAG00000023411

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000026167; ENSECAP00000021808; ENSECAG00000023411

Phylogenomic databases

GeneTreeiENSGT00940000155245

Gene expression databases

BgeeiENSECAG00000023411, Expressed in liver and 15 other tissues
ExpressionAtlasiF6XRV0, baseline

Family and domain databases

InterProiView protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23
PANTHERiPTHR24025:SF18, PTHR24025:SF18, 1 hit
PfamiView protein in Pfam
PF00028, Cadherin, 24 hits
PRINTSiPR00205, CADHERIN
SMARTiView protein in SMART
SM00112, CA, 26 hits
SUPFAMiSSF49313, SSF49313, 27 hits
PROSITEiView protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6XRV0_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6XRV0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: December 2, 2020
This is version 53 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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