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UniProtKB - F6XRV0 (F6XRV0_HORSE)

Entry version 53 (02 Dec 2020)
Sequence version 3 (11 Dec 2019)
Previous versions | rss
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Protein
Submitted name:

Uncharacterized protein

Gene

CDH23

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDH23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3071 – 3094HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_502381545624 – 3358Sequence analysisAdd BLAST3335

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSECAG00000023411, Expressed in liver and 15 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F6XRV0, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 132CadherinInterPro annotationAdd BLAST91
Domaini133 – 240CadherinInterPro annotationAdd BLAST108
Domaini241 – 352CadherinInterPro annotationAdd BLAST112
Domaini353 – 464CadherinInterPro annotationAdd BLAST112
Domaini465 – 565CadherinInterPro annotationAdd BLAST101
Domaini566 – 675CadherinInterPro annotationAdd BLAST110
Domaini676 – 788CadherinInterPro annotationAdd BLAST113
Domaini783 – 894CadherinInterPro annotationAdd BLAST112
Domaini895 – 999CadherinInterPro annotationAdd BLAST105
Domaini1000 – 1106CadherinInterPro annotationAdd BLAST107
Domaini1107 – 1212CadherinInterPro annotationAdd BLAST106
Domaini1214 – 1317CadherinInterPro annotationAdd BLAST104
Domaini1318 – 1422CadherinInterPro annotationAdd BLAST105
Domaini1424 – 1531CadherinInterPro annotationAdd BLAST108
Domaini1533 – 1638CadherinInterPro annotationAdd BLAST106
Domaini1639 – 1748CadherinInterPro annotationAdd BLAST110
Domaini1763 – 1855CadherinInterPro annotationAdd BLAST93
Domaini1856 – 1963CadherinInterPro annotationAdd BLAST108
Domaini1964 – 2073CadherinInterPro annotationAdd BLAST110
Domaini2074 – 2178CadherinInterPro annotationAdd BLAST105
Domaini2179 – 2297CadherinInterPro annotationAdd BLAST119
Domaini2301 – 2406CadherinInterPro annotationAdd BLAST106
Domaini2407 – 2513CadherinInterPro annotationAdd BLAST107
Domaini2514 – 2615CadherinInterPro annotationAdd BLAST102
Domaini2618 – 2726CadherinInterPro annotationAdd BLAST109
Domaini2733 – 2850CadherinInterPro annotationAdd BLAST118
Domaini2851 – 2979CadherinInterPro annotationAdd BLAST129

Keywords - Domaini

RepeatARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155245

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23

The PANTHER Classification System

More...PANTHERi		PTHR24025:SF18, PTHR24025:SF18, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00028, Cadherin, 24 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00205, CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00112, CA, 26 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49313, SSF49313, 27 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

F6XRV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRCHVATGCH VVWLFVLISG SWGQVNRLPF FTNHFFDTYL LISEDTPVGS 
        60         70         80         90        100
SVTQLLARDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE 
       110        120        130        140        150
FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPEVGAGNTP 
       160        170        180        190        200
VGTPIFIVNA TDPDLGAGGS VLYSFQPPSL FFAIDSARGI VTVIRELDYE 
       210        220        230        240        250
TTQAYQLTVN ATDQDKTRPL STLANLAIII TDIQDMDPIF INLPYSTNIY 
       260        270        280        290        300
EHSPPGTTVR IITAIDQDKG RPRGIGYTIV SGNTNSIFAL DYISGALTLN 
       310        320        330        340        350
GLLDRENPLY SHGFILTVKG TELNDDRTPS NATVTTTFNI LVIDINDNAP 
       360        370        380        390        400
EFNSSEYSVA ITELAQVGFA LPLFIQVVDK DENLGLNSMF EVYLVGNNSH 
       410        420        430        440        450
HFIISPTSVQ GKADIRIRVA IPLDFETVDR YDFDLFANES VPDHVGYAKV 
       460        470        480        490        500
KITLINENDN RPIFSQPLYN ISLYENVTVG TSVLTVLATD NDVGTFGEVN 
       510        520        530        540        550
YFFSDDPDRF SLDKDTGLIM LIARLDYELI QRFTLTVIAR DGGGEETTGR 
       560        570        580        590        600
VRINVLDVND NAPTFQKDAY VGALRENEPS VTQLVRLRAT DEDSPPNNQI 
       610        620        630        640        650
TYSIVSASAF GSYFDISVYE GYGVISVSRP LDYEQIPNGL IYLMVMAKDA 
       660        670        680        690        700
GNPPLNSTVP VTIEVFDEND NPPTFSKPAY FVSVVENIMA GATVLFLNAT 
       710        720        730        740        750
DLDRSREYGQ ESIIYSLEGS SQFRINARSG EITTTSLLDR ETKSEYILIV 
       760        770        780        790        800
RAVDGGVGHN QKTGIATVNI TILDINDNHP AWKDAPYYIN LVEMTPPDSD 
       810        820        830        840        850
VTTVVAVDPD LGENGTLVYS IQPPNKFYSL NSSTGKIRTT HVMLDRENPD 
       860        870        880        890        900
PHEAELMRKI VVSVTDCGRP PLRATSSATV FVNLLDLNDN DPTFQNLPFV 
       910        920        930        940        950
AEVLEGTPAG VSIYQVVAID LDEGLNGLVT YRMQVGMPRM DFLINSSSGV 
       960        970        980        990       1000
VVTTTELDRE RIAEYQLRVV ASDAGTPTKS STSTLTIRVL DVNDETPTFF 
      1010       1020       1030       1040       1050
PAVYNVSVSE DVPREFRVVW LNCTDNDVGL NAELSYFITG GNVDGKFSVG 
      1060       1070       1080       1090       1100
YRDAVVRTVV SLDRETTASY TLVLEAIDNG PVGKRRTGTA TVFITVLDVN 
      1110       1120       1130       1140       1150
DNRPIFLQSS YEASVPEDIP EGHSIVQLKA TDADEGEFGR VWYRILQGNH 
      1160       1170       1180       1190       1200
GNNFRIHVSS GLLMRGPRSL DRERNSSHVL IVEAYNHDLG PMRSSVRVIV 
      1210       1220       1230       1240       1250
YVEDVNDEAP VFTQQQYSRL GLRETAGIGT SVIVVRATDR DTGDGGLVNY 
      1260       1270       1280       1290       1300
RILSGAEGKF EVDESTGLII TVEYLDYETK TSYLMNVSAT DQAPPFNQGF 
      1310       1320       1330       1340       1350
CSVYVTLLNE LDEAVQFSNA SYEAAILENL ALGTEIVRVQ AYSIDNLNQI 
      1360       1370       1380       1390       1400
TYRFDAYTSA QAKALFKIDA ITGVITVKGL VDREKGDFYT LTVVADDGGP 
      1410       1420       1430       1440       1450
KVDSTVKVYI TVLDENDNSP RFDFTSDSAV SVPEDCPVGQ RMATVKARDP 
      1460       1470       1480       1490       1500
DAGSNGQVVF SLASGNIAGA FEIITTNDST GEVFVARPLD REELDHYILK 
      1510       1520       1530       1540       1550
VVASDRGTPP RKKDHILQVT ILDVNDNPPV IESPFGYNVS VNENVGGGTA 
      1560       1570       1580       1590       1600
VVQVRASDRD IGINSILSYY ITKGNEDMTF RMDRISGEIA TRPAPPDRER 
      1610       1620       1630       1640       1650
QSFYHLVVTV EDEGTPTLSA TTHVYVTIVD ENDNTPVFQQ PHYEILLDEG 
      1660       1670       1680       1690       1700
PDTINTSLIT IQALDLDEGP NGTVAYAIVT GNIINTFRIN SHSGVISAAK 
      1710       1720       1730       1740       1750
ELDYEISQGR YTLIVTATDQ CPILSRRLTS TATVLVNVND INDNVPTFPR 
      1760       1770       1780       1790       1800
DYEGPFDVTE GQPGPRVWTF LAHDRDSGPN GQVEYGILDG DPLGEFVISP 
      1810       1820       1830       1840       1850
VEGVLRVRKD VELDRETIAF YNLTICARDR GMPPLSSTML VGIRVLDIND 
      1860       1870       1880       1890       1900
NDPVLLNLPM NITISENSPI SSFVAHVLAS DADSGCNALL TFNITAGNRE 
      1910       1920       1930       1940       1950
RAFSINATTG IVTVNRPLDR ERIPDYKLTI SVKDNPDNPR IARRDFDLLL 
      1960       1970       1980       1990       2000
IFLVDENDNQ PLFTESTYQA EVMENSPAGT PLTVLNGPIL ALDADLDVYA 
      2010       2020       2030       2040       2050
VVTYQLLGSQ SGLFDINNST GMVTVRSGVI IDREAFSPPV LELLLLAEDI 
      2060       2070       2080       2090       2100
GLLNSTADLL VTILDDNDNF PTFSPATLTV HLLENCPPGF SVLQVTATDE 
      2110       2120       2130       2140       2150
DSGLNGELIY RIEAGAQDRF LIHPVTGVIR VGNATIDREE QESYRLTVVA 
      2160       2170       2180       2190       2200
TDRGTVPLSG TAIITILIDD INDSRPEFLN PIQTVSVLES VEPGTVIANV 
      2210       2220       2230       2240       2250
TAIDRDLDPK LEYRIIGIVA KDDTDRLVPD QEDAFAVNIN TGSVMVKSPL 
      2260       2270       2280       2290       2300
NRELVATYEV TLSVIDNASD LPERSVSVPN AKLTVNILDV NDNTPQFKPF 
      2310       2320       2330       2340       2350
GITYYTERIL EGATLGTTLI AVAAVDPDKG LNGLITYTLL DLMPPGYVQL 
      2360       2370       2380       2390       2400
EDSSAGKVIA NRTVDYEEVH WLNFTVRASD NGSPPRAAEI PVYLEIVDIN 
      2410       2420       2430       2440       2450
DNNPIFDQPS YQEAVFEDVP VGTVILTVTA TDADSGNFAL VEYSLGDGEG 
      2460       2470       2480       2490       2500
KFAINPVTGD IYVLSSLDRE KKDHYILTAL AKDNPGDAAS NRRENSVQVV 
      2510       2520       2530       2540       2550
IQVLDINDCR PQFSKPQFST SVYENEPAGT SVITMMATDQ DEGSNGELAY 
      2560       2570       2580       2590       2600
SLEGPGVEAF YVDIDSGLVT TKRPLQSYER FNLTVVATDG GQPPLWGTTM 
      2610       2620       2630       2640       2650
LLVEVIDVND NRPIFVRPPN GTILHIREET PLRSNVYEVY ATDKDEGLNG 
      2660       2670       2680       2690       2700
AVRYSFLKTA GNRDWEYFTI DPISGLIQTA QRLDREKQAV YSLILVASDL 
      2710       2720       2730       2740       2750
GQPVPYETMQ PLQVALEDID DNEPLFVRPP KGSPQYQLLT VPEHSPHGTL 
      2760       2770       2780       2790       2800
VGNVTGAVDA DEGPNAIVYY FIAAGNEEKN FHLHPDGRLL VLRDLDRERE 
      2810       2820       2830       2840       2850
AVFSFIVKAS SNSSWTPPRG PSPALDLVTD LTLQEVRVVL EDINDQPPRF 
      2860       2870       2880       2890       2900
TKAEYTAGVA TDAKVGSELI QVLALDADIG NNSLVFYSIL AIHYFRALAN 
      2910       2920       2930       2940       2950
DSEDMGQVFT MGSMDGILRT FDLFMAYSPG YFVVDIVARD LAGHNDTAVI 
      2960       2970       2980       2990       3000
GIYILRDDQR VKIVINEIPD RVRDFEEEFI RLLSNITGAI VNTDDVQFHV 
      3010       3020       3030       3040       3050
DKKGRVNFAQ TELLIHVVNR ETNRILDVDR VIQMIDENKE QLRNLFRNYN 
      3060       3070       3080       3090       3100
VLDVQPAISV RLPDDMSALQ MAIIVLAILL FLAAMLFILM NWYYRTIHKR 
      3110       3120       3130       3140       3150
KLKAIVAGSA GNRGFIDIMD MPNTNKYSFD GANPVWLDPF CRNLELAAQA 
      3160       3170       3180       3190       3200
EHEDDLPENL SEIADLWNSP TRTHGTFGRE PAAVKPDDDR YLRAAIQEYD 
      3210       3220       3230       3240       3250
NIAKLGQIIR EGPIKGSLLK VVLEDYLRLK KLFAQRMVQK AASCHSSISE 
      3260       3270       3280       3290       3300
LIPTELEEEP GECSPGQGSL RFCHKPPTEL KGPDGIHMVH GSTGTLLATD 
      3310       3320       3330       3340       3350
LNSLPEDDQK GLGRSLETLT AAEASAFERN ARTESAKSTP LHKLRDVIME 

SPLEITEL
Length:3,358
Mass (Da):369,646
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB0C8F3E2BC186BE9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XLQ0F6XLQ0_HORSE
Uncharacterized protein
CDH23
3,353Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6XLL6F6XLL6_HORSE
Uncharacterized protein
CDH23
1,079Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GRP0A0A3Q2GRP0_HORSE
Uncharacterized protein
CDH23
1,380Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HCH9A0A3Q2HCH9_HORSE
Uncharacterized protein
CDH23
1,048Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HD56A0A3Q2HD56_HORSE
Uncharacterized protein
CDH23
525Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSECAT00000026167; ENSECAP00000021808; ENSECAG00000023411

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000026167; ENSECAP00000021808; ENSECAG00000023411

Phylogenomic databases

GeneTreeiENSGT00940000155245

Gene expression databases

BgeeiENSECAG00000023411, Expressed in liver and 15 other tissues
ExpressionAtlasiF6XRV0, baseline

Family and domain databases

InterProiView protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23
PANTHERiPTHR24025:SF18, PTHR24025:SF18, 1 hit
PfamiView protein in Pfam
PF00028, Cadherin, 24 hits
PRINTSiPR00205, CADHERIN
SMARTiView protein in SMART
SM00112, CA, 26 hits
SUPFAMiSSF49313, SSF49313, 27 hits
PROSITEiView protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6XRV0_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6XRV0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: December 2, 2020
This is version 53 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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