Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 53 (02 Dec 2020)
Sequence version 3 (11 Dec 2019)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

CDH23

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDH23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3066 – 3089HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_502388999624 – 3353Sequence analysisAdd BLAST3330

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000023411, Expressed in liver and 15 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6XLQ0, baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 132CadherinInterPro annotationAdd BLAST91
Domaini133 – 236CadherinInterPro annotationAdd BLAST104
Domaini237 – 348CadherinInterPro annotationAdd BLAST112
Domaini349 – 459CadherinInterPro annotationAdd BLAST111
Domaini460 – 560CadherinInterPro annotationAdd BLAST101
Domaini561 – 670CadherinInterPro annotationAdd BLAST110
Domaini671 – 783CadherinInterPro annotationAdd BLAST113
Domaini778 – 889CadherinInterPro annotationAdd BLAST112
Domaini890 – 994CadherinInterPro annotationAdd BLAST105
Domaini995 – 1101CadherinInterPro annotationAdd BLAST107
Domaini1102 – 1207CadherinInterPro annotationAdd BLAST106
Domaini1209 – 1312CadherinInterPro annotationAdd BLAST104
Domaini1313 – 1417CadherinInterPro annotationAdd BLAST105
Domaini1419 – 1526CadherinInterPro annotationAdd BLAST108
Domaini1528 – 1633CadherinInterPro annotationAdd BLAST106
Domaini1634 – 1743CadherinInterPro annotationAdd BLAST110
Domaini1758 – 1850CadherinInterPro annotationAdd BLAST93
Domaini1851 – 1958CadherinInterPro annotationAdd BLAST108
Domaini1959 – 2068CadherinInterPro annotationAdd BLAST110
Domaini2069 – 2173CadherinInterPro annotationAdd BLAST105
Domaini2174 – 2292CadherinInterPro annotationAdd BLAST119
Domaini2296 – 2401CadherinInterPro annotationAdd BLAST106
Domaini2402 – 2508CadherinInterPro annotationAdd BLAST107
Domaini2509 – 2610CadherinInterPro annotationAdd BLAST102
Domaini2613 – 2721CadherinInterPro annotationAdd BLAST109
Domaini2728 – 2845CadherinInterPro annotationAdd BLAST118
Domaini2846 – 2974CadherinInterPro annotationAdd BLAST129

Keywords - Domaini

RepeatARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155245

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23

The PANTHER Classification System

More...
PANTHERi
PTHR24025:SF18, PTHR24025:SF18, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00028, Cadherin, 24 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205, CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112, CA, 26 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313, SSF49313, 27 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

F6XLQ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRCHVATGCH VVWLFVLISG SWGQVNRLPF FTNHFFDTYL LISEDTPVGS
60 70 80 90 100
SVTQLLARDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE
110 120 130 140 150
FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPENTPVGTP
160 170 180 190 200
IFIVNATDPD LGAGGSVLYS FQPPSLFFAI DSARGIVTVI RELDYETTQA
210 220 230 240 250
YQLTVNATDQ DKTRPLSTLA NLAIIITDIQ DMDPIFINLP YSTNIYEHSP
260 270 280 290 300
PGTTVRIITA IDQDKGRPRG IGYTIVSGNT NSIFALDYIS GALTLNGLLD
310 320 330 340 350
RENPLYSHGF ILTVKGTELN DDRTPSNATV TTTFNILVID INDNAPEFNS
360 370 380 390 400
SEYSVAITEL AQVGFALPLF IQVVDKDETG LNSMFEVYLV GNNSHHFIIS
410 420 430 440 450
PTSVQGKADI RIRVAIPLDF ETVDRYDFDL FANESVPDHV GYAKVKITLI
460 470 480 490 500
NENDNRPIFS QPLYNISLYE NVTVGTSVLT VLATDNDVGT FGEVNYFFSD
510 520 530 540 550
DPDRFSLDKD TGLIMLIARL DYELIQRFTL TVIARDGGGE ETTGRVRINV
560 570 580 590 600
LDVNDNAPTF QKDAYVGALR ENEPSVTQLV RLRATDEDSP PNNQITYSIV
610 620 630 640 650
SASAFGSYFD ISVYEGYGVI SVSRPLDYEQ IPNGLIYLMV MAKDAGNPPL
660 670 680 690 700
NSTVPVTIEV FDENDNPPTF SKPAYFVSVV ENIMAGATVL FLNATDLDRS
710 720 730 740 750
REYGQESIIY SLEGSSQFRI NARSGEITTT SLLDRETKSE YILIVRAVDG
760 770 780 790 800
GVGHNQKTGI ATVNITILDI NDNHPAWKDA PYYINLVEMT PPDSDVTTVV
810 820 830 840 850
AVDPDLGENG TLVYSIQPPN KFYSLNSSTG KIRTTHVMLD RENPDPHEAE
860 870 880 890 900
LMRKIVVSVT DCGRPPLRAT SSATVFVNLL DLNDNDPTFQ NLPFVAEVLE
910 920 930 940 950
GTPAGVSIYQ VVAIDLDEGL NGLVTYRMQV GMPRMDFLIN SSSGVVVTTT
960 970 980 990 1000
ELDRERIAEY QLRVVASDAG TPTKSSTSTL TIRVLDVNDE TPTFFPAVYN
1010 1020 1030 1040 1050
VSVSEDVPRE FRVVWLNCTD NDVGLNAELS YFITGGNVDG KFSVGYRDAV
1060 1070 1080 1090 1100
VRTVVSLDRE TTASYTLVLE AIDNGPVGKR RTGTATVFIT VLDVNDNRPI
1110 1120 1130 1140 1150
FLQSSYEASV PEDIPEGHSI VQLKATDADE GEFGRVWYRI LQGNHGNNFR
1160 1170 1180 1190 1200
IHVSSGLLMR GPRSLDRERN SSHVLIVEAY NHDLGPMRSS VRVIVYVEDV
1210 1220 1230 1240 1250
NDEAPVFTQQ QYSRLGLRET AGIGTSVIVV RATDRDTGDG GLVNYRILSG
1260 1270 1280 1290 1300
AEGKFEVDES TGLIITVEYL DYETKTSYLM NVSATDQAPP FNQGFCSVYV
1310 1320 1330 1340 1350
TLLNELDEAV QFSNASYEAA ILENLALGTE IVRVQAYSID NLNQITYRFD
1360 1370 1380 1390 1400
AYTSAQAKAL FKIDAITGVI TVKGLVDREK GDFYTLTVVA DDGGPKVDST
1410 1420 1430 1440 1450
VQVYITVLDE NDNSPRFDFT SDSAVSVPED CPVGQRMATV KARDPDAGSN
1460 1470 1480 1490 1500
GQVVFSLASG NIAGAFEIIT TNDSTGEVFV ARPLDREELD HYILKVVASD
1510 1520 1530 1540 1550
RGTPPRKKDH ILQVTILDVN DNPPVIESPF GYNVSVNENV GGGTAVVQVR
1560 1570 1580 1590 1600
ASDRDIGINS ILSYYITKGN EDMTFRMDRI SGEIATRPAP PDRERQSFYH
1610 1620 1630 1640 1650
LVVTVEDEGT PTLSATTHVY VTIVDENDNT PVFQQPHYEI LLDEGPDTIN
1660 1670 1680 1690 1700
TSLITIQALD LDEGPNGTVA YAIVTGNIIN TFRINSHSGV ISAAKELDYE
1710 1720 1730 1740 1750
ISQGRYTLIV TATDQCPILS RRLTSTATVL VNVNDINDNV PTFPRDYEGP
1760 1770 1780 1790 1800
FDVTEGQPGP RVWTFLAHDR DSGPNGQVEY GILDGDPLGE FVISPVEGVL
1810 1820 1830 1840 1850
RVRKDVELDR ETIAFYNLTI CARDRGMPPL SSTMLVGIRV LDINDNDPVL
1860 1870 1880 1890 1900
LNLPMNITIS ENSPISSFVA HVLASDADSG CNALLTFNIT AGNRERAFSI
1910 1920 1930 1940 1950
NATTGIVTVN RPLDRERIPD YKLTISVKDN PDNPRIARRD FDLLLIFLVD
1960 1970 1980 1990 2000
ENDNQPLFTE STYQAEVMEN SPAGTPLTVL NGPILALDAD LDVYAVVTYQ
2010 2020 2030 2040 2050
LLGSQSGLFD INNSTGMVTV RSGVIIDREA FSPPVLELLL LAEDIGLLNS
2060 2070 2080 2090 2100
TADLLVTILD DNDNFPTFSP ATLTVHLLEN CPPGFSVLQV TATDEDSGLN
2110 2120 2130 2140 2150
GELIYRIEAG AQDRFLIHPV TGVIRVGNAT IDREEQESYR LTVVATDRGT
2160 2170 2180 2190 2200
VPLSGTAIIT ILIDDINDSR PEFLNPIQTV SVLESVEPGT VIANVTAIDR
2210 2220 2230 2240 2250
DLDPKLEYRI IGIVAKDDTD RLVPDQEDAF AVNINTGSVM VKSPLNRELV
2260 2270 2280 2290 2300
ATYEVTLSVI DNASDLPERS VSVPNAKLTV NILDVNDNTP QFKPFGITYY
2310 2320 2330 2340 2350
TERILEGATL GTTLIAVAAV DPDKGLNGLI TYTLLDLMPP GYVQLEDSSA
2360 2370 2380 2390 2400
GKVIANRTVD YEEVHWLNFT VRASDNGSPP RAAEIPVYLE IVDINDNNPI
2410 2420 2430 2440 2450
FDQPSYQEAV FEDVPVGTVI LTVTATDADS GNFALVEYSL GDGEGKFAIN
2460 2470 2480 2490 2500
PVTGDIYVLS SLDREKKDHY ILTALAKDNP GDAASNRREN SVQVVIQVLD
2510 2520 2530 2540 2550
INDCRPQFSK PQFSTSVYEN EPAGTSVITM MATDQDEGSN GELAYSLEGP
2560 2570 2580 2590 2600
GVEAFYVDID SGLVTTKRPL QSYERFNLTV VATDGGQPPL WGTTMLLVEV
2610 2620 2630 2640 2650
IDVNDNRPIF VRPPNGTILH IREETPLRSN VYEVYATDKD EGLNGAVRYS
2660 2670 2680 2690 2700
FLKTAGNRDW EYFTIDPISG LIQTAQRLDR EKQAVYSLIL VASDLGQPVP
2710 2720 2730 2740 2750
YETMQPLQVA LEDIDDNEPL FVRPPKGSPQ YQLLTVPEHS PHGTLVGNVT
2760 2770 2780 2790 2800
GAVDADEGPN AIVYYFIAAG NEEKNFHLHP DGRLLVLRDL DREREAVFSF
2810 2820 2830 2840 2850
IVKASSNSSW TPPRGPSPAL DLVTDLTLQE VRVVLEDIND QPPRFTKAEY
2860 2870 2880 2890 2900
TAGVATDAKV GSELIQVLAL DADIGNNSLV FYSILAIHYF RALANDSEDM
2910 2920 2930 2940 2950
GQVFTMGSMD GILRTFDLFM AYSPGYFVVD IVARDLAGHN DTAVIGIYIL
2960 2970 2980 2990 3000
RDDQRVKIVI NEIPDRVRDF EEEFIRLLSN ITGAIVNTDD VQFHVDKKGR
3010 3020 3030 3040 3050
VNFAQTELLI HVVNRETNRI LDVDRVIQMI DENKEQLRNL FRNYNVLDVQ
3060 3070 3080 3090 3100
PAISVRLPDD MSALQMAIIV LAILLFLAAM LFILMNWYYR TIHKRKLKAI
3110 3120 3130 3140 3150
VAGSAGNRGF IDIMDMPNTN KYSFDGANPV WLDPFCRNLE LAAQAEHEDD
3160 3170 3180 3190 3200
LPENLSEIAD LWNSPTRTHG TFGREPAAVK PDDDRYLRAA IQEYDNIAKL
3210 3220 3230 3240 3250
GQIIREGPIK GSLLKVVLED YLRLKKLFAQ RMVQKAASCH SSISELIPTE
3260 3270 3280 3290 3300
LEEEPGECSP GQGSLRFCHK PPTELKGPDG IHMVHGSTGT LLATDLNSLP
3310 3320 3330 3340 3350
EDDQKGLGRS LETLTAAEAS AFERNARTES AKSTPLHKLR DVIMESPLEI

TEL
Length:3,353
Mass (Da):369,236
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF6C38556457B5D0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XRV0F6XRV0_HORSE
Uncharacterized protein
CDH23
3,358Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6XLL6F6XLL6_HORSE
Uncharacterized protein
CDH23
1,079Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GRP0A0A3Q2GRP0_HORSE
Uncharacterized protein
CDH23
1,380Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HCH9A0A3Q2HCH9_HORSE
Uncharacterized protein
CDH23
1,048Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HD56A0A3Q2HD56_HORSE
Uncharacterized protein
CDH23
525Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000026182; ENSECAP00000021822; ENSECAG00000023411

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000026182; ENSECAP00000021822; ENSECAG00000023411

Phylogenomic databases

GeneTreeiENSGT00940000155245

Gene expression databases

BgeeiENSECAG00000023411, Expressed in liver and 15 other tissues
ExpressionAtlasiF6XLQ0, baseline

Family and domain databases

InterProiView protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23
PANTHERiPTHR24025:SF18, PTHR24025:SF18, 1 hit
PfamiView protein in Pfam
PF00028, Cadherin, 24 hits
PRINTSiPR00205, CADHERIN
SMARTiView protein in SMART
SM00112, CA, 26 hits
SUPFAMiSSF49313, SSF49313, 27 hits
PROSITEiView protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6XLQ0_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6XLQ0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: December 2, 2020
This is version 53 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again