UniProtKB - F6XLQ0 (F6XLQ0_HORSE)
Protein
Submitted name:
Uncharacterized protein
Gene
CDH23
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- calcium ion binding Source: InterPro
GO - Biological processi
- homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
- inner ear receptor cell stereocilium organization Source: InterPro
- locomotory behavior Source: InterPro
- sensory perception of sound Source: InterPro
Keywordsi
Ligand | CalciumPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Gene namesi | Name:CDH23Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Subcellular locationi
Plasma Membrane
- plasma membrane Source: UniProtKB-KW
Other locations
- integral component of membrane Source: UniProtKB-KW
- stereocilium Source: InterPro
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 3066 – 3089 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
Cell membraneARBA annotation, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5023889996 | 24 – 3353 | Sequence analysisAdd BLAST | 3330 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000023411, Expressed in liver and 15 other tissues |
ExpressionAtlasi | F6XLQ0, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 42 – 132 | CadherinInterPro annotationAdd BLAST | 91 | |
Domaini | 133 – 236 | CadherinInterPro annotationAdd BLAST | 104 | |
Domaini | 237 – 348 | CadherinInterPro annotationAdd BLAST | 112 | |
Domaini | 349 – 459 | CadherinInterPro annotationAdd BLAST | 111 | |
Domaini | 460 – 560 | CadherinInterPro annotationAdd BLAST | 101 | |
Domaini | 561 – 670 | CadherinInterPro annotationAdd BLAST | 110 | |
Domaini | 671 – 783 | CadherinInterPro annotationAdd BLAST | 113 | |
Domaini | 778 – 889 | CadherinInterPro annotationAdd BLAST | 112 | |
Domaini | 890 – 994 | CadherinInterPro annotationAdd BLAST | 105 | |
Domaini | 995 – 1101 | CadherinInterPro annotationAdd BLAST | 107 | |
Domaini | 1102 – 1207 | CadherinInterPro annotationAdd BLAST | 106 | |
Domaini | 1209 – 1312 | CadherinInterPro annotationAdd BLAST | 104 | |
Domaini | 1313 – 1417 | CadherinInterPro annotationAdd BLAST | 105 | |
Domaini | 1419 – 1526 | CadherinInterPro annotationAdd BLAST | 108 | |
Domaini | 1528 – 1633 | CadherinInterPro annotationAdd BLAST | 106 | |
Domaini | 1634 – 1743 | CadherinInterPro annotationAdd BLAST | 110 | |
Domaini | 1758 – 1850 | CadherinInterPro annotationAdd BLAST | 93 | |
Domaini | 1851 – 1958 | CadherinInterPro annotationAdd BLAST | 108 | |
Domaini | 1959 – 2068 | CadherinInterPro annotationAdd BLAST | 110 | |
Domaini | 2069 – 2173 | CadherinInterPro annotationAdd BLAST | 105 | |
Domaini | 2174 – 2292 | CadherinInterPro annotationAdd BLAST | 119 | |
Domaini | 2296 – 2401 | CadherinInterPro annotationAdd BLAST | 106 | |
Domaini | 2402 – 2508 | CadherinInterPro annotationAdd BLAST | 107 | |
Domaini | 2509 – 2610 | CadherinInterPro annotationAdd BLAST | 102 | |
Domaini | 2613 – 2721 | CadherinInterPro annotationAdd BLAST | 109 | |
Domaini | 2728 – 2845 | CadherinInterPro annotationAdd BLAST | 118 | |
Domaini | 2846 – 2974 | CadherinInterPro annotationAdd BLAST | 129 |
Keywords - Domaini
RepeatARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000155245 |
Family and domain databases
InterProi | View protein in InterPro IPR002126, Cadherin-like_dom IPR015919, Cadherin-like_sf IPR020894, Cadherin_CS IPR033030, CDH23 |
PANTHERi | PTHR24025:SF18, PTHR24025:SF18, 1 hit |
Pfami | View protein in Pfam PF00028, Cadherin, 24 hits |
PRINTSi | PR00205, CADHERIN |
SMARTi | View protein in SMART SM00112, CA, 26 hits |
SUPFAMi | SSF49313, SSF49313, 27 hits |
PROSITEi | View protein in PROSITE PS00232, CADHERIN_1, 12 hits PS50268, CADHERIN_2, 27 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
F6XLQ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRCHVATGCH VVWLFVLISG SWGQVNRLPF FTNHFFDTYL LISEDTPVGS
60 70 80 90 100
SVTQLLARDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE
110 120 130 140 150
FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPENTPVGTP
160 170 180 190 200
IFIVNATDPD LGAGGSVLYS FQPPSLFFAI DSARGIVTVI RELDYETTQA
210 220 230 240 250
YQLTVNATDQ DKTRPLSTLA NLAIIITDIQ DMDPIFINLP YSTNIYEHSP
260 270 280 290 300
PGTTVRIITA IDQDKGRPRG IGYTIVSGNT NSIFALDYIS GALTLNGLLD
310 320 330 340 350
RENPLYSHGF ILTVKGTELN DDRTPSNATV TTTFNILVID INDNAPEFNS
360 370 380 390 400
SEYSVAITEL AQVGFALPLF IQVVDKDETG LNSMFEVYLV GNNSHHFIIS
410 420 430 440 450
PTSVQGKADI RIRVAIPLDF ETVDRYDFDL FANESVPDHV GYAKVKITLI
460 470 480 490 500
NENDNRPIFS QPLYNISLYE NVTVGTSVLT VLATDNDVGT FGEVNYFFSD
510 520 530 540 550
DPDRFSLDKD TGLIMLIARL DYELIQRFTL TVIARDGGGE ETTGRVRINV
560 570 580 590 600
LDVNDNAPTF QKDAYVGALR ENEPSVTQLV RLRATDEDSP PNNQITYSIV
610 620 630 640 650
SASAFGSYFD ISVYEGYGVI SVSRPLDYEQ IPNGLIYLMV MAKDAGNPPL
660 670 680 690 700
NSTVPVTIEV FDENDNPPTF SKPAYFVSVV ENIMAGATVL FLNATDLDRS
710 720 730 740 750
REYGQESIIY SLEGSSQFRI NARSGEITTT SLLDRETKSE YILIVRAVDG
760 770 780 790 800
GVGHNQKTGI ATVNITILDI NDNHPAWKDA PYYINLVEMT PPDSDVTTVV
810 820 830 840 850
AVDPDLGENG TLVYSIQPPN KFYSLNSSTG KIRTTHVMLD RENPDPHEAE
860 870 880 890 900
LMRKIVVSVT DCGRPPLRAT SSATVFVNLL DLNDNDPTFQ NLPFVAEVLE
910 920 930 940 950
GTPAGVSIYQ VVAIDLDEGL NGLVTYRMQV GMPRMDFLIN SSSGVVVTTT
960 970 980 990 1000
ELDRERIAEY QLRVVASDAG TPTKSSTSTL TIRVLDVNDE TPTFFPAVYN
1010 1020 1030 1040 1050
VSVSEDVPRE FRVVWLNCTD NDVGLNAELS YFITGGNVDG KFSVGYRDAV
1060 1070 1080 1090 1100
VRTVVSLDRE TTASYTLVLE AIDNGPVGKR RTGTATVFIT VLDVNDNRPI
1110 1120 1130 1140 1150
FLQSSYEASV PEDIPEGHSI VQLKATDADE GEFGRVWYRI LQGNHGNNFR
1160 1170 1180 1190 1200
IHVSSGLLMR GPRSLDRERN SSHVLIVEAY NHDLGPMRSS VRVIVYVEDV
1210 1220 1230 1240 1250
NDEAPVFTQQ QYSRLGLRET AGIGTSVIVV RATDRDTGDG GLVNYRILSG
1260 1270 1280 1290 1300
AEGKFEVDES TGLIITVEYL DYETKTSYLM NVSATDQAPP FNQGFCSVYV
1310 1320 1330 1340 1350
TLLNELDEAV QFSNASYEAA ILENLALGTE IVRVQAYSID NLNQITYRFD
1360 1370 1380 1390 1400
AYTSAQAKAL FKIDAITGVI TVKGLVDREK GDFYTLTVVA DDGGPKVDST
1410 1420 1430 1440 1450
VQVYITVLDE NDNSPRFDFT SDSAVSVPED CPVGQRMATV KARDPDAGSN
1460 1470 1480 1490 1500
GQVVFSLASG NIAGAFEIIT TNDSTGEVFV ARPLDREELD HYILKVVASD
1510 1520 1530 1540 1550
RGTPPRKKDH ILQVTILDVN DNPPVIESPF GYNVSVNENV GGGTAVVQVR
1560 1570 1580 1590 1600
ASDRDIGINS ILSYYITKGN EDMTFRMDRI SGEIATRPAP PDRERQSFYH
1610 1620 1630 1640 1650
LVVTVEDEGT PTLSATTHVY VTIVDENDNT PVFQQPHYEI LLDEGPDTIN
1660 1670 1680 1690 1700
TSLITIQALD LDEGPNGTVA YAIVTGNIIN TFRINSHSGV ISAAKELDYE
1710 1720 1730 1740 1750
ISQGRYTLIV TATDQCPILS RRLTSTATVL VNVNDINDNV PTFPRDYEGP
1760 1770 1780 1790 1800
FDVTEGQPGP RVWTFLAHDR DSGPNGQVEY GILDGDPLGE FVISPVEGVL
1810 1820 1830 1840 1850
RVRKDVELDR ETIAFYNLTI CARDRGMPPL SSTMLVGIRV LDINDNDPVL
1860 1870 1880 1890 1900
LNLPMNITIS ENSPISSFVA HVLASDADSG CNALLTFNIT AGNRERAFSI
1910 1920 1930 1940 1950
NATTGIVTVN RPLDRERIPD YKLTISVKDN PDNPRIARRD FDLLLIFLVD
1960 1970 1980 1990 2000
ENDNQPLFTE STYQAEVMEN SPAGTPLTVL NGPILALDAD LDVYAVVTYQ
2010 2020 2030 2040 2050
LLGSQSGLFD INNSTGMVTV RSGVIIDREA FSPPVLELLL LAEDIGLLNS
2060 2070 2080 2090 2100
TADLLVTILD DNDNFPTFSP ATLTVHLLEN CPPGFSVLQV TATDEDSGLN
2110 2120 2130 2140 2150
GELIYRIEAG AQDRFLIHPV TGVIRVGNAT IDREEQESYR LTVVATDRGT
2160 2170 2180 2190 2200
VPLSGTAIIT ILIDDINDSR PEFLNPIQTV SVLESVEPGT VIANVTAIDR
2210 2220 2230 2240 2250
DLDPKLEYRI IGIVAKDDTD RLVPDQEDAF AVNINTGSVM VKSPLNRELV
2260 2270 2280 2290 2300
ATYEVTLSVI DNASDLPERS VSVPNAKLTV NILDVNDNTP QFKPFGITYY
2310 2320 2330 2340 2350
TERILEGATL GTTLIAVAAV DPDKGLNGLI TYTLLDLMPP GYVQLEDSSA
2360 2370 2380 2390 2400
GKVIANRTVD YEEVHWLNFT VRASDNGSPP RAAEIPVYLE IVDINDNNPI
2410 2420 2430 2440 2450
FDQPSYQEAV FEDVPVGTVI LTVTATDADS GNFALVEYSL GDGEGKFAIN
2460 2470 2480 2490 2500
PVTGDIYVLS SLDREKKDHY ILTALAKDNP GDAASNRREN SVQVVIQVLD
2510 2520 2530 2540 2550
INDCRPQFSK PQFSTSVYEN EPAGTSVITM MATDQDEGSN GELAYSLEGP
2560 2570 2580 2590 2600
GVEAFYVDID SGLVTTKRPL QSYERFNLTV VATDGGQPPL WGTTMLLVEV
2610 2620 2630 2640 2650
IDVNDNRPIF VRPPNGTILH IREETPLRSN VYEVYATDKD EGLNGAVRYS
2660 2670 2680 2690 2700
FLKTAGNRDW EYFTIDPISG LIQTAQRLDR EKQAVYSLIL VASDLGQPVP
2710 2720 2730 2740 2750
YETMQPLQVA LEDIDDNEPL FVRPPKGSPQ YQLLTVPEHS PHGTLVGNVT
2760 2770 2780 2790 2800
GAVDADEGPN AIVYYFIAAG NEEKNFHLHP DGRLLVLRDL DREREAVFSF
2810 2820 2830 2840 2850
IVKASSNSSW TPPRGPSPAL DLVTDLTLQE VRVVLEDIND QPPRFTKAEY
2860 2870 2880 2890 2900
TAGVATDAKV GSELIQVLAL DADIGNNSLV FYSILAIHYF RALANDSEDM
2910 2920 2930 2940 2950
GQVFTMGSMD GILRTFDLFM AYSPGYFVVD IVARDLAGHN DTAVIGIYIL
2960 2970 2980 2990 3000
RDDQRVKIVI NEIPDRVRDF EEEFIRLLSN ITGAIVNTDD VQFHVDKKGR
3010 3020 3030 3040 3050
VNFAQTELLI HVVNRETNRI LDVDRVIQMI DENKEQLRNL FRNYNVLDVQ
3060 3070 3080 3090 3100
PAISVRLPDD MSALQMAIIV LAILLFLAAM LFILMNWYYR TIHKRKLKAI
3110 3120 3130 3140 3150
VAGSAGNRGF IDIMDMPNTN KYSFDGANPV WLDPFCRNLE LAAQAEHEDD
3160 3170 3180 3190 3200
LPENLSEIAD LWNSPTRTHG TFGREPAAVK PDDDRYLRAA IQEYDNIAKL
3210 3220 3230 3240 3250
GQIIREGPIK GSLLKVVLED YLRLKKLFAQ RMVQKAASCH SSISELIPTE
3260 3270 3280 3290 3300
LEEEPGECSP GQGSLRFCHK PPTELKGPDG IHMVHGSTGT LLATDLNSLP
3310 3320 3330 3340 3350
EDDQKGLGRS LETLTAAEAS AFERNARTES AKSTPLHKLR DVIMESPLEI
TEL
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF6XRV0 | F6XRV0_HORSE | Uncharacterized protein | CDH23 | 3,358 | Annotation score: | ||
F6XLL6 | F6XLL6_HORSE | Uncharacterized protein | CDH23 | 1,079 | Annotation score: | ||
A0A3Q2GRP0 | A0A3Q2GRP0_HORSE | Uncharacterized protein | CDH23 | 1,380 | Annotation score: | ||
A0A3Q2HCH9 | A0A3Q2HCH9_HORSE | Uncharacterized protein | CDH23 | 1,048 | Annotation score: | ||
A0A3Q2HD56 | A0A3Q2HD56_HORSE | Uncharacterized protein | CDH23 | 525 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000026182; ENSECAP00000021822; ENSECAG00000023411 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSECAT00000026182; ENSECAP00000021822; ENSECAG00000023411 |
Phylogenomic databases
GeneTreei | ENSGT00940000155245 |
Gene expression databases
Bgeei | ENSECAG00000023411, Expressed in liver and 15 other tissues |
ExpressionAtlasi | F6XLQ0, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR002126, Cadherin-like_dom IPR015919, Cadherin-like_sf IPR020894, Cadherin_CS IPR033030, CDH23 |
PANTHERi | PTHR24025:SF18, PTHR24025:SF18, 1 hit |
Pfami | View protein in Pfam PF00028, Cadherin, 24 hits |
PRINTSi | PR00205, CADHERIN |
SMARTi | View protein in SMART SM00112, CA, 26 hits |
SUPFAMi | SSF49313, SSF49313, 27 hits |
PROSITEi | View protein in PROSITE PS00232, CADHERIN_1, 12 hits PS50268, CADHERIN_2, 27 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6XLQ0_HORSE | |
Accessioni | F6XLQ0Primary (citable) accession number: F6XLQ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 53 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |