Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - F6XLQ0 (F6XLQ0_HORSE)

Entry version 53 (02 Dec 2020)
Sequence version 3 (11 Dec 2019)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

CDH23

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDH23Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3066 – 3089HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_502388999624 – 3353Sequence analysisAdd BLAST3330

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSECAG00000023411, Expressed in liver and 15 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F6XLQ0, baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 132CadherinInterPro annotationAdd BLAST91
Domaini133 – 236CadherinInterPro annotationAdd BLAST104
Domaini237 – 348CadherinInterPro annotationAdd BLAST112
Domaini349 – 459CadherinInterPro annotationAdd BLAST111
Domaini460 – 560CadherinInterPro annotationAdd BLAST101
Domaini561 – 670CadherinInterPro annotationAdd BLAST110
Domaini671 – 783CadherinInterPro annotationAdd BLAST113
Domaini778 – 889CadherinInterPro annotationAdd BLAST112
Domaini890 – 994CadherinInterPro annotationAdd BLAST105
Domaini995 – 1101CadherinInterPro annotationAdd BLAST107
Domaini1102 – 1207CadherinInterPro annotationAdd BLAST106
Domaini1209 – 1312CadherinInterPro annotationAdd BLAST104
Domaini1313 – 1417CadherinInterPro annotationAdd BLAST105
Domaini1419 – 1526CadherinInterPro annotationAdd BLAST108
Domaini1528 – 1633CadherinInterPro annotationAdd BLAST106
Domaini1634 – 1743CadherinInterPro annotationAdd BLAST110
Domaini1758 – 1850CadherinInterPro annotationAdd BLAST93
Domaini1851 – 1958CadherinInterPro annotationAdd BLAST108
Domaini1959 – 2068CadherinInterPro annotationAdd BLAST110
Domaini2069 – 2173CadherinInterPro annotationAdd BLAST105
Domaini2174 – 2292CadherinInterPro annotationAdd BLAST119
Domaini2296 – 2401CadherinInterPro annotationAdd BLAST106
Domaini2402 – 2508CadherinInterPro annotationAdd BLAST107
Domaini2509 – 2610CadherinInterPro annotationAdd BLAST102
Domaini2613 – 2721CadherinInterPro annotationAdd BLAST109
Domaini2728 – 2845CadherinInterPro annotationAdd BLAST118
Domaini2846 – 2974CadherinInterPro annotationAdd BLAST129

Keywords - Domaini

RepeatARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155245

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23

The PANTHER Classification System

More...PANTHERi		PTHR24025:SF18, PTHR24025:SF18, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00028, Cadherin, 24 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00205, CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00112, CA, 26 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49313, SSF49313, 27 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

F6XLQ0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRCHVATGCH VVWLFVLISG SWGQVNRLPF FTNHFFDTYL LISEDTPVGS 
        60         70         80         90        100
SVTQLLARDM DNDPLVFGVS GEEASRFFAV EPDTGVVWLR QPLDRETKSE 
       110        120        130        140        150
FTVEFSVSDH QGVITRKVNI QVGDVNDNAP TFHNQPYSVR IPENTPVGTP 
       160        170        180        190        200
IFIVNATDPD LGAGGSVLYS FQPPSLFFAI DSARGIVTVI RELDYETTQA 
       210        220        230        240        250
YQLTVNATDQ DKTRPLSTLA NLAIIITDIQ DMDPIFINLP YSTNIYEHSP 
       260        270        280        290        300
PGTTVRIITA IDQDKGRPRG IGYTIVSGNT NSIFALDYIS GALTLNGLLD 
       310        320        330        340        350
RENPLYSHGF ILTVKGTELN DDRTPSNATV TTTFNILVID INDNAPEFNS 
       360        370        380        390        400
SEYSVAITEL AQVGFALPLF IQVVDKDETG LNSMFEVYLV GNNSHHFIIS 
       410        420        430        440        450
PTSVQGKADI RIRVAIPLDF ETVDRYDFDL FANESVPDHV GYAKVKITLI 
       460        470        480        490        500
NENDNRPIFS QPLYNISLYE NVTVGTSVLT VLATDNDVGT FGEVNYFFSD 
       510        520        530        540        550
DPDRFSLDKD TGLIMLIARL DYELIQRFTL TVIARDGGGE ETTGRVRINV 
       560        570        580        590        600
LDVNDNAPTF QKDAYVGALR ENEPSVTQLV RLRATDEDSP PNNQITYSIV 
       610        620        630        640        650
SASAFGSYFD ISVYEGYGVI SVSRPLDYEQ IPNGLIYLMV MAKDAGNPPL 
       660        670        680        690        700
NSTVPVTIEV FDENDNPPTF SKPAYFVSVV ENIMAGATVL FLNATDLDRS 
       710        720        730        740        750
REYGQESIIY SLEGSSQFRI NARSGEITTT SLLDRETKSE YILIVRAVDG 
       760        770        780        790        800
GVGHNQKTGI ATVNITILDI NDNHPAWKDA PYYINLVEMT PPDSDVTTVV 
       810        820        830        840        850
AVDPDLGENG TLVYSIQPPN KFYSLNSSTG KIRTTHVMLD RENPDPHEAE 
       860        870        880        890        900
LMRKIVVSVT DCGRPPLRAT SSATVFVNLL DLNDNDPTFQ NLPFVAEVLE 
       910        920        930        940        950
GTPAGVSIYQ VVAIDLDEGL NGLVTYRMQV GMPRMDFLIN SSSGVVVTTT 
       960        970        980        990       1000
ELDRERIAEY QLRVVASDAG TPTKSSTSTL TIRVLDVNDE TPTFFPAVYN 
      1010       1020       1030       1040       1050
VSVSEDVPRE FRVVWLNCTD NDVGLNAELS YFITGGNVDG KFSVGYRDAV 
      1060       1070       1080       1090       1100
VRTVVSLDRE TTASYTLVLE AIDNGPVGKR RTGTATVFIT VLDVNDNRPI 
      1110       1120       1130       1140       1150
FLQSSYEASV PEDIPEGHSI VQLKATDADE GEFGRVWYRI LQGNHGNNFR 
      1160       1170       1180       1190       1200
IHVSSGLLMR GPRSLDRERN SSHVLIVEAY NHDLGPMRSS VRVIVYVEDV 
      1210       1220       1230       1240       1250
NDEAPVFTQQ QYSRLGLRET AGIGTSVIVV RATDRDTGDG GLVNYRILSG 
      1260       1270       1280       1290       1300
AEGKFEVDES TGLIITVEYL DYETKTSYLM NVSATDQAPP FNQGFCSVYV 
      1310       1320       1330       1340       1350
TLLNELDEAV QFSNASYEAA ILENLALGTE IVRVQAYSID NLNQITYRFD 
      1360       1370       1380       1390       1400
AYTSAQAKAL FKIDAITGVI TVKGLVDREK GDFYTLTVVA DDGGPKVDST 
      1410       1420       1430       1440       1450
VQVYITVLDE NDNSPRFDFT SDSAVSVPED CPVGQRMATV KARDPDAGSN 
      1460       1470       1480       1490       1500
GQVVFSLASG NIAGAFEIIT TNDSTGEVFV ARPLDREELD HYILKVVASD 
      1510       1520       1530       1540       1550
RGTPPRKKDH ILQVTILDVN DNPPVIESPF GYNVSVNENV GGGTAVVQVR 
      1560       1570       1580       1590       1600
ASDRDIGINS ILSYYITKGN EDMTFRMDRI SGEIATRPAP PDRERQSFYH 
      1610       1620       1630       1640       1650
LVVTVEDEGT PTLSATTHVY VTIVDENDNT PVFQQPHYEI LLDEGPDTIN 
      1660       1670       1680       1690       1700
TSLITIQALD LDEGPNGTVA YAIVTGNIIN TFRINSHSGV ISAAKELDYE 
      1710       1720       1730       1740       1750
ISQGRYTLIV TATDQCPILS RRLTSTATVL VNVNDINDNV PTFPRDYEGP 
      1760       1770       1780       1790       1800
FDVTEGQPGP RVWTFLAHDR DSGPNGQVEY GILDGDPLGE FVISPVEGVL 
      1810       1820       1830       1840       1850
RVRKDVELDR ETIAFYNLTI CARDRGMPPL SSTMLVGIRV LDINDNDPVL 
      1860       1870       1880       1890       1900
LNLPMNITIS ENSPISSFVA HVLASDADSG CNALLTFNIT AGNRERAFSI 
      1910       1920       1930       1940       1950
NATTGIVTVN RPLDRERIPD YKLTISVKDN PDNPRIARRD FDLLLIFLVD 
      1960       1970       1980       1990       2000
ENDNQPLFTE STYQAEVMEN SPAGTPLTVL NGPILALDAD LDVYAVVTYQ 
      2010       2020       2030       2040       2050
LLGSQSGLFD INNSTGMVTV RSGVIIDREA FSPPVLELLL LAEDIGLLNS 
      2060       2070       2080       2090       2100
TADLLVTILD DNDNFPTFSP ATLTVHLLEN CPPGFSVLQV TATDEDSGLN 
      2110       2120       2130       2140       2150
GELIYRIEAG AQDRFLIHPV TGVIRVGNAT IDREEQESYR LTVVATDRGT 
      2160       2170       2180       2190       2200
VPLSGTAIIT ILIDDINDSR PEFLNPIQTV SVLESVEPGT VIANVTAIDR 
      2210       2220       2230       2240       2250
DLDPKLEYRI IGIVAKDDTD RLVPDQEDAF AVNINTGSVM VKSPLNRELV 
      2260       2270       2280       2290       2300
ATYEVTLSVI DNASDLPERS VSVPNAKLTV NILDVNDNTP QFKPFGITYY 
      2310       2320       2330       2340       2350
TERILEGATL GTTLIAVAAV DPDKGLNGLI TYTLLDLMPP GYVQLEDSSA 
      2360       2370       2380       2390       2400
GKVIANRTVD YEEVHWLNFT VRASDNGSPP RAAEIPVYLE IVDINDNNPI 
      2410       2420       2430       2440       2450
FDQPSYQEAV FEDVPVGTVI LTVTATDADS GNFALVEYSL GDGEGKFAIN 
      2460       2470       2480       2490       2500
PVTGDIYVLS SLDREKKDHY ILTALAKDNP GDAASNRREN SVQVVIQVLD 
      2510       2520       2530       2540       2550
INDCRPQFSK PQFSTSVYEN EPAGTSVITM MATDQDEGSN GELAYSLEGP 
      2560       2570       2580       2590       2600
GVEAFYVDID SGLVTTKRPL QSYERFNLTV VATDGGQPPL WGTTMLLVEV 
      2610       2620       2630       2640       2650
IDVNDNRPIF VRPPNGTILH IREETPLRSN VYEVYATDKD EGLNGAVRYS 
      2660       2670       2680       2690       2700
FLKTAGNRDW EYFTIDPISG LIQTAQRLDR EKQAVYSLIL VASDLGQPVP 
      2710       2720       2730       2740       2750
YETMQPLQVA LEDIDDNEPL FVRPPKGSPQ YQLLTVPEHS PHGTLVGNVT 
      2760       2770       2780       2790       2800
GAVDADEGPN AIVYYFIAAG NEEKNFHLHP DGRLLVLRDL DREREAVFSF 
      2810       2820       2830       2840       2850
IVKASSNSSW TPPRGPSPAL DLVTDLTLQE VRVVLEDIND QPPRFTKAEY 
      2860       2870       2880       2890       2900
TAGVATDAKV GSELIQVLAL DADIGNNSLV FYSILAIHYF RALANDSEDM 
      2910       2920       2930       2940       2950
GQVFTMGSMD GILRTFDLFM AYSPGYFVVD IVARDLAGHN DTAVIGIYIL 
      2960       2970       2980       2990       3000
RDDQRVKIVI NEIPDRVRDF EEEFIRLLSN ITGAIVNTDD VQFHVDKKGR 
      3010       3020       3030       3040       3050
VNFAQTELLI HVVNRETNRI LDVDRVIQMI DENKEQLRNL FRNYNVLDVQ 
      3060       3070       3080       3090       3100
PAISVRLPDD MSALQMAIIV LAILLFLAAM LFILMNWYYR TIHKRKLKAI 
      3110       3120       3130       3140       3150
VAGSAGNRGF IDIMDMPNTN KYSFDGANPV WLDPFCRNLE LAAQAEHEDD 
      3160       3170       3180       3190       3200
LPENLSEIAD LWNSPTRTHG TFGREPAAVK PDDDRYLRAA IQEYDNIAKL 
      3210       3220       3230       3240       3250
GQIIREGPIK GSLLKVVLED YLRLKKLFAQ RMVQKAASCH SSISELIPTE 
      3260       3270       3280       3290       3300
LEEEPGECSP GQGSLRFCHK PPTELKGPDG IHMVHGSTGT LLATDLNSLP 
      3310       3320       3330       3340       3350
EDDQKGLGRS LETLTAAEAS AFERNARTES AKSTPLHKLR DVIMESPLEI 

TEL
Length:3,353
Mass (Da):369,236
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF6C38556457B5D0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XRV0F6XRV0_HORSE
Uncharacterized protein
CDH23
3,358Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6XLL6F6XLL6_HORSE
Uncharacterized protein
CDH23
1,079Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GRP0A0A3Q2GRP0_HORSE
Uncharacterized protein
CDH23
1,380Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HCH9A0A3Q2HCH9_HORSE
Uncharacterized protein
CDH23
1,048Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HD56A0A3Q2HD56_HORSE
Uncharacterized protein
CDH23
525Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSECAT00000026182; ENSECAP00000021822; ENSECAG00000023411

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000026182; ENSECAP00000021822; ENSECAG00000023411

Phylogenomic databases

GeneTreeiENSGT00940000155245

Gene expression databases

BgeeiENSECAG00000023411, Expressed in liver and 15 other tissues
ExpressionAtlasiF6XLQ0, baseline

Family and domain databases

InterProiView protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR033030, CDH23
PANTHERiPTHR24025:SF18, PTHR24025:SF18, 1 hit
PfamiView protein in Pfam
PF00028, Cadherin, 24 hits
PRINTSiPR00205, CADHERIN
SMARTiView protein in SMART
SM00112, CA, 26 hits
SUPFAMiSSF49313, SSF49313, 27 hits
PROSITEiView protein in PROSITE
PS00232, CADHERIN_1, 12 hits
PS50268, CADHERIN_2, 27 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6XLQ0_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6XLQ0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: December 2, 2020
This is version 53 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again