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Entry version 72 (29 Sep 2021)
Sequence version 4 (02 Jun 2021)
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Protein
Submitted name:

Adenomatous polyposis coli

Gene

mrps14

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processWnt signaling pathwayARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Adenomatous polyposis coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mrps14Imported
Synonyms:apcImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-480855, apc
XB-GENE-975794, mrps14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6XK08

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000021501, Expressed in embryo and 12 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6XK08, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000046491

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 55APC_N_CCInterPro annotationAdd BLAST52
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati662 – 704ARMPROSITE-ProRule annotationAdd BLAST43
Domaini2227 – 2553APC_basicInterPro annotationAdd BLAST327

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni80 – 112DisorderedSequence analysisAdd BLAST33
Regioni239 – 301DisorderedSequence analysisAdd BLAST63
Regioni832 – 878DisorderedSequence analysisAdd BLAST47
Regioni901 – 942DisorderedSequence analysisAdd BLAST42
Regioni963 – 990DisorderedSequence analysisAdd BLAST28
Regioni1033 – 1265DisorderedSequence analysisAdd BLAST233
Regioni1278 – 1387DisorderedSequence analysisAdd BLAST110
Regioni1425 – 1481DisorderedSequence analysisAdd BLAST57
Regioni1534 – 1614DisorderedSequence analysisAdd BLAST81
Regioni1664 – 1722DisorderedSequence analysisAdd BLAST59
Regioni1756 – 1948DisorderedSequence analysisAdd BLAST193
Regioni1968 – 2012DisorderedSequence analysisAdd BLAST45
Regioni2044 – 2079DisorderedSequence analysisAdd BLAST36
Regioni2158 – 2546DisorderedSequence analysisAdd BLAST389

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili6 – 54Sequence analysisAdd BLAST49
Coiled coili134 – 154Sequence analysisAdd BLAST21
Coiled coili532 – 552Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi245 – 263Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi266 – 301Polar residuesSequence analysisAdd BLAST36
Compositional biasi860 – 878Polar residuesSequence analysisAdd BLAST19
Compositional biasi901 – 915Polar residuesSequence analysisAdd BLAST15
Compositional biasi926 – 940Polar residuesSequence analysisAdd BLAST15
Compositional biasi1033 – 1048Polar residuesSequence analysisAdd BLAST16
Compositional biasi1050 – 1066Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1078 – 1092Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1101 – 1130Polar residuesSequence analysisAdd BLAST30
Compositional biasi1131 – 1183Basic and acidic residuesSequence analysisAdd BLAST53
Compositional biasi1189 – 1265Polar residuesSequence analysisAdd BLAST77
Compositional biasi1301 – 1315Polar residuesSequence analysisAdd BLAST15
Compositional biasi1338 – 1381Polar residuesSequence analysisAdd BLAST44
Compositional biasi1456 – 1475Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi1540 – 1566Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi1664 – 1689Polar residuesSequence analysisAdd BLAST26
Compositional biasi1690 – 1706Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1756 – 1775Polar residuesSequence analysisAdd BLAST20
Compositional biasi1801 – 1816Polar residuesSequence analysisAdd BLAST16
Compositional biasi1817 – 1841Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi1864 – 1899Basic and acidic residuesSequence analysisAdd BLAST36
Compositional biasi2173 – 2194Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi2202 – 2229Polar residuesSequence analysisAdd BLAST28
Compositional biasi2260 – 2427Polar residuesSequence analysisAdd BLAST168
Compositional biasi2462 – 2500Polar residuesSequence analysisAdd BLAST39
Compositional biasi2516 – 2531Basic and acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the adenomatous polyposis coli (APC) family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2122, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063749

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001012_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6XK08

Identification of Orthologs from Complete Genome Data

More...
OMAi
EVPRVYC

TreeFam database of animal gene trees

More...
TreeFami
TF106496

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026836, APC
IPR009240, APC_15aa_rpt
IPR009234, APC_basic_dom
IPR026831, APC_dom
IPR026818, Apc_fam
IPR032038, APC_N
IPR036149, APC_N_sf
IPR041257, APC_rep
IPR009223, APC_rpt
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR000225, Armadillo
IPR009224, SAMP

The PANTHER Classification System

More...
PANTHERi
PTHR12607, PTHR12607, 1 hit
PTHR12607:SF11, PTHR12607:SF11, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05972, APC_15aa, 2 hits
PF05956, APC_basic, 1 hit
PF16689, APC_N_CC, 1 hit
PF05923, APC_r, 7 hits
PF18797, APC_rep, 1 hit
PF00514, Arm, 1 hit
PF05924, SAMP, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00185, ARM, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit
SSF58050, SSF58050, 1 hit
SSF82931, SSF82931, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50176, ARM_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6XK08-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAASYDQLL KQVAALKMEN TNLRQELEDN SNHLTKLESE ASNMKEVLKQ
60 70 80 90 100
LQGSIEDEAM ASSGQIDLLE RLKELNLDSS NFPAGKTRPK MSMRSYGSRE
110 120 130 140 150
GSLSGHSGEC SPVPVGSFQR RGLLNGSRES TGYLEELEKE RLLLIAEHEK
160 170 180 190 200
EEKEKRWYYA QLQNLTKRID SLPLTENFSL QTDMTRRQLE YEARQIRAAM
210 220 230 240 250
EEQLGTCQDM EKRVQTRVGK IQQIEEDILR IRQLLQSQAA EAAERTPQSK
260 270 280 290 300
HDAGSRDADK LPDGQGTSEI VTSSNVGSGQ GSSSRADHDT ASVMSSNSTY
310 320 330 340 350
SVPRRLTSHL GTKVEMVYSL LSMLGTHDKD DMSRTLLAMS SSQDSCIAMR
360 370 380 390 400
QSGCLPLLIQ LLHGNDKDSV LLGNSRGSKE ARARASAALH NIIHSQPDDK
410 420 430 440 450
RGRREIRVLH LLEQIRAYCE TCWEWQEAHE QGMDQDKNPM PAPVDHQICP
460 470 480 490 500
AVCVLMKLSF DEEHRHAMNE LGGLQAIAEL LQVDCEMYGL INDHYSVTLR
510 520 530 540 550
RYAGMALTNL TFGDVANKAT LCSMKSCMRA LVAQLKSESE DLQQVIASVL
560 570 580 590 600
RNLSWRADVN SKKTLREVGS VKALMECALD VKKESTLKSV LSALWNLSAH
610 620 630 640 650
CTENKADICS VDGALAFLVG TLTYRSQTNT LAIIESGGGI LRNVSSLIAT
660 670 680 690 700
NEDHRQILRE NNCLQTLLQH LKSHSLTIVS NACGTLWNLS ARNAKDQEAL
710 720 730 740 750
WDMGAVSMLK NLIHSKHKMI AMGSAAALRN LMANRPAKYK DANIMSPGSS
760 770 780 790 800
VPSLHVRKQK ALEAELDAQH LSETFDNIDN LSPKTTHRNK QRHKQNLCSE
810 820 830 840 850
YVLDSSRHDD SICRSDNFSL GNLTVLSPYI NSTVLPGSSS PRPTMEGNRP
860 870 880 890 900
EKDRERTAGL SNYHSATENS GNSSKRIGVQ LSTTAQISKV MDEVSNIHMV
910 920 930 940 950
QEDRSSGSAS EMHCMSDERT SQRKPSSNHP HSNPFSFAKG DSSNRGCPVA
960 970 980 990 1000
FMKMEYKMAS NDSLNSVSST DGYGKRGQVK PSVESYSEDD EGKFGSYGHY
1010 1020 1030 1040 1050
PAGLAHKIHS ANHMDDNDTE LDTPINYSLK YSDEQLNSGR QSPSQNERWA
1060 1070 1080 1090 1100
RPKHIIDSEM KQSEQRQPRT TKTTYSSYTE NKEEKHKKFP PHFNQPENAP
1110 1120 1130 1140 1150
AYARSRGTNN QADQSRVGSN LSNNSKASKP HCQVDDYDDD KTTNFSERYS
1160 1170 1180 1190 1200
EGEQQEDENE RQNKYNIKPY ASDEHHGEQP IDYSRKYPTD VPSSAQKPSF
1210 1220 1230 1240 1250
PYSNNPSKQK PKKEQVSSSS NTPTPSPNSG RQNQLHPNSA QTRPGLNRPK
1260 1270 1280 1290 1300
QTSSKPPSIT QETIQTYCVE DTPICFSRGS SLSSLSSAED EIEGRERSSR
1310 1320 1330 1340 1350
GQESNNTLQI TEPKENKSAV SKDGAINETR SSVHHTRTKN NRLQTSNISP
1360 1370 1380 1390 1400
SDSSRHKSVE FSSGAKSPSK SGAQTPKSPP EHYVQETPLM FSRCTSVSSL
1410 1420 1430 1440 1450
DSFESHSIAS SIASSVASEH MISGIISPSD LPDSPGQTMP PSRSKTPPPP
1460 1470 1480 1490 1500
QTVHAKKDSS KPKVSGEERD KVAKQTGVHS AIQRVQVLQE ADTLLHFATE
1510 1520 1530 1540 1550
STPDGFSCAS SLSALSLDEP YIQKDVELKI MPPVLENDQG NEAEPEKEST
1560 1570 1580 1590 1600
DNLNKKENKR SEQEKDMLDD TDDDIDILEE CIISAMPRKP SRKNKKVPQP
1610 1620 1630 1640 1650
TAGKPPPPVA RKPSQLPVYK LLSSQNRLQT QKHVNFTHSD DMPRVYCVEG
1660 1670 1680 1690 1700
TPINFSTATS LSDLTIESPP NELTNNDQPN TGSLSTDLEK RDTIPTEGRS
1710 1720 1730 1740 1750
TDDTDASKKL NPSTSVLDED KAEEGDILAE CIHSAMPKGK SHKPYRVKKI
1760 1770 1780 1790 1800
MDQINHTSAG TSSGNNRSMQ EIDKNKPTSP VKPMPQSIEF KGRLKKNTES
1810 1820 1830 1840 1850
KLNPSSENQY SDPRKQNSKN TSKDANEKIP NNEERTKGFA FDSPHHYTPI
1860 1870 1880 1890 1900
EGTPYCFSRN DSLSSLDFDD DDIDLSKEKA ELRKEKGTKD TDRKGKYKNE
1910 1920 1930 1940 1950
NPAINQIGKQ EQVGPKSLEG RGQPKALVHK PTSFCPAAKG TQDRGGAKDE
1960 1970 1980 1990 2000
KMQNFAIENT PVCFSRNSSL SSLSDIDQEN NNKETEPIKQ TEMTETQIGL
2010 2020 2030 2040 2050
RRPQTSGYAP KSFHVEDTPV CFSRNSSLSS LSIDSEDDLL QECISSAMPK
2060 2070 2080 2090 2100
KKKPSKAKNE GEKSSSNSVG GILAEEPDLT LDLRDLQSPD SENAFSPDSE
2110 2120 2130 2140 2150
NFDWKAIQEG ANSIVSRLHQ AAAAGSLSRQ GSSDSDSILS LKSGISLGSP
2160 2170 2180 2190 2200
FHLTSDKEEK TITCNKGPKI VKPSDKSALE NKKTEDEPKG IKGGKKVYKS
2210 2220 2230 2240 2250
LITGKSRSSS DFSSHCKQSV QTNMPSISRG RTMIHIPGVR ASSPSTSPVS
2260 2270 2280 2290 2300
KKGPVFKNAP SKSPNENQSL SNSPKGSKPL KSESFYGSRQ SSTSGGSSKG
2310 2320 2330 2340 2350
NSRSGSRDSV SSRPSSQQLS RPLQSPGRNS ISPGRNGISP PNKFSQLPRT
2360 2370 2380 2390 2400
SSPSTASTKS SGSGRMSYTS PGRQLSQPNL SKQSGLPKTP SSIPRSESAS
2410 2420 2430 2440 2450
KGLNQNVNTG PNKKVELSRM SSTKSSGSES DRSERPALVR QSTFIKEAPS
2460 2470 2480 2490 2500
PTLRRKLEES ASFESLSSSS RADSPTRSQT QTPALSPSLP DMSLSTHSIQ
2510 2520 2530 2540 2550
AGGWRKMPPN LNPAAEHGDS RRRHDISRSH SESPSRLPIT RSVKKQRVKM
2560 2570
KSSKFVPFSD LNQSAHLLQK ELGEK
Length:2,575
Mass (Da):283,548
Last modified:June 2, 2021 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64F94B20FF8E3FDD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6I8R5H6A0A6I8R5H6_XENTR
Adenomatous polyposis coli
apc
2,833Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_002931484.1, XM_002931438.4
XP_002936457.1, XM_002936411.4
XP_002936458.1, XM_002936412.4
XP_004910521.1, XM_004910464.3
XP_004910522.1, XM_004910465.3
XP_004910523.1, XM_004910466.3
XP_017945374.1, XM_018089885.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000046491; ENSXETP00000046491; ENSXETG00000021501

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100485757
779466

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xtr:100485757
xtr:779466

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_002931484.1, XM_002931438.4
XP_002936457.1, XM_002936411.4
XP_002936458.1, XM_002936412.4
XP_004910521.1, XM_004910464.3
XP_004910522.1, XM_004910465.3
XP_004910523.1, XM_004910466.3
XP_017945374.1, XM_018089885.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000046491

Proteomic databases

PaxDbiF6XK08

Genome annotation databases

EnsembliENSXETT00000046491; ENSXETP00000046491; ENSXETG00000021501
GeneIDi100485757
779466
KEGGixtr:100485757
xtr:779466

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
324
63931
XenbaseiXB-GENE-480855, apc
XB-GENE-975794, mrps14

Phylogenomic databases

eggNOGiKOG2122, Eukaryota
GeneTreeiENSGT00530000063749
HOGENOMiCLU_001012_0_0_1
InParanoidiF6XK08
OMAiEVPRVYC
TreeFamiTF106496

Gene expression databases

BgeeiENSXETG00000021501, Expressed in embryo and 12 other tissues
ExpressionAtlasiF6XK08, baseline

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR026836, APC
IPR009240, APC_15aa_rpt
IPR009234, APC_basic_dom
IPR026831, APC_dom
IPR026818, Apc_fam
IPR032038, APC_N
IPR036149, APC_N_sf
IPR041257, APC_rep
IPR009223, APC_rpt
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR000225, Armadillo
IPR009224, SAMP
PANTHERiPTHR12607, PTHR12607, 1 hit
PTHR12607:SF11, PTHR12607:SF11, 1 hit
PfamiView protein in Pfam
PF05972, APC_15aa, 2 hits
PF05956, APC_basic, 1 hit
PF16689, APC_N_CC, 1 hit
PF05923, APC_r, 7 hits
PF18797, APC_rep, 1 hit
PF00514, Arm, 1 hit
PF05924, SAMP, 3 hits
SMARTiView protein in SMART
SM00185, ARM, 7 hits
SUPFAMiSSF48371, SSF48371, 1 hit
SSF58050, SSF58050, 1 hit
SSF82931, SSF82931, 1 hit
PROSITEiView protein in PROSITE
PS50176, ARM_REPEAT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6XK08_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6XK08
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: June 2, 2021
Last modified: September 29, 2021
This is version 72 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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