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Entry version 68 (11 Dec 2019)
Sequence version 1 (27 Jul 2011)
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Protein
Submitted name:

Microtubule-actin cross-linking factor 1

Gene

Macf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Microtubule-actin cross-linking factor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Macf1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:108559 Macf1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F6XCT0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
F6XCT0

PeptideAtlas

More...
PeptideAtlasi
F6XCT0

PRoteomics IDEntifications database

More...
PRIDEi
F6XCT0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028649 Expressed in 318 organ(s), highest expression level in lung

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6XCT0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F6XCT0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini36 – 139Calponin-homology (CH)InterPro annotationAdd BLAST104
Domaini152 – 256Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini826 – 883SH3InterPro annotationAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili20 – 40Sequence analysisAdd BLAST21
Coiled coili203 – 223Sequence analysisAdd BLAST21
Coiled coili435 – 455Sequence analysisAdd BLAST21
Coiled coili460 – 487Sequence analysisAdd BLAST28
Coiled coili779 – 799Sequence analysisAdd BLAST21
Coiled coili1004 – 1024Sequence analysisAdd BLAST21
Coiled coili1361 – 1391Sequence analysisAdd BLAST31
Coiled coili1480 – 1507Sequence analysisAdd BLAST28
Coiled coili1587 – 1614Sequence analysisAdd BLAST28
Coiled coili1740 – 1778Sequence analysisAdd BLAST39

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0516 Eukaryota
COG5069 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155824

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR041573 Desmoplakin_Spectrin-like
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 2 hits
PF17902 SH3_10, 1 hit
PF00435 Spectrin, 1 hit
PF18373 Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 2 hits
SM00150 SPEC, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576 SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 18 potential isoforms that are computationally mapped.Show allAlign All

F6XCT0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGYVPGQQP ANRSQEKEFV QAYEDVLERY KDERDRVQKK TFTKWVNKHL
60 70 80 90 100
MKVRKHINDL YEDLRDGHNL ISLLEVLSGI KLPREKGRMR FHRLQNVQIA
110 120 130 140 150
LDFLKQRQVK LVNIRNDDIT DGNPKLTLGL IWTIILHFQI SDIYISGESG
160 170 180 190 200
DMSAKEKLLL WTQKVTAGYT GVKCTNFSSC WSDGKMFNAL IHRYRPDLVD
210 220 230 240 250
MERVQVQSNR ENLEQAFEVA ERLGVTRLLD AEDVDVPSPD EKSVITYVSS
260 270 280 290 300
IYDAFPKVPE GGEGISATEV DSRWQEYQSR VDSLIPWIRQ HTILMSDKSF
310 320 330 340 350
PQNPVELKAL YNQYIHFKET EILAKEREKG RIKELYKLLE VWIEFGRIKL
360 370 380 390 400
PQGYHPNHVE EEWGKLIVEM LEREKSLRPA VERLELLLQI ANKIQNGALN
410 420 430 440 450
CEEKLTLAKN TLQADAAHLE SGQPVQCESD VIMYIQECEG LIRQLQVDLQ
460 470 480 490 500
ILRDEKYYQL EELAFRVMRL QDELVTLRLE CTNLYRKGHF SSLELVPPST
510 520 530 540 550
LTTTHLKAEP LNKTTHSSST SWFRKPMTRT ELVSISSSED EGNLRFVYEL
560 570 580 590 600
LSWVEEMQMK LERAEWGNDL PSVELQLETQ QHIHTSVEEL GSSVKEARLY
610 620 630 640 650
EGKMSQNFHT SYVETLGKLE TQYCKLKETS SFRMRHLQSL HKFVSRATAE
660 670 680 690 700
LIWLNGKEEE ELACDWSDSN PNISAKKTYF SELTMELEGK QDVFRSLQDT
710 720 730 740 750
AEVLSLENHP AKQTVEAYSA AVQSQLQWMK QLCLCVEQHV KENAAYFQFF
760 770 780 790 800
SDARDLESFL RNLQDSIKRK YTCDRSTSLS RLEDLLQDSM DEKEQLIQSK
810 820 830 840 850
SSVASLVGRS KTIVQLKPRN PDHVLKSTLS VKAICDYRQI EITICKNDEC
860 870 880 890 900
VLEDNSQRTK WKVISPTGNE AMVPSVCFLI PPPNKEAIEM ASRVEQSYQK
910 920 930 940 950
VMALWHQLHI NTKSLISWNY LRKDLDTVQT WSLEKLRSLA PGECHQVMKN
960 970 980 990 1000
LQAHYEDFLQ DSHDSALFSV ADRLRIEEEV EACKAHFQHL MKSLENEDKE
1010 1020 1030 1040 1050
ETLAKVYISE LKNIRLLLEE CEQRLLKQIQ SPASSKTDRD ARQDITLRIA
1060 1070 1080 1090 1100
EQEHTQEDLQ HLRSDLDAIS MKCNVFLQQS PSGSSATTLR SELNLMVEKM
1110 1120 1130 1140 1150
DHVYGLSTVY LNKLKTIDVI VRSMQDAELL VKGYEIKLSQ EEAVPADLSA
1160 1170 1180 1190 1200
LESHRTTLQH WLSDVKDKNS VFSVLDEEIT KAKKVAEQLR HPASEPNLDL
1210 1220 1230 1240 1250
ERYQEKGSQL QERWHRVIAQ LETRQSEVES IQEVLRDYRA CHGTLIKWIE
1260 1270 1280 1290 1300
ETTAQQEMMK PGQAEDSRVL SEQLSQQTEL FAEIERNQTK LDQCQKFSQQ
1310 1320 1330 1340 1350
YSTIVKDYEL QLMTYKAFVE SQQKSPGKRR RMISSSDAIT QEFMDLRTRY
1360 1370 1380 1390 1400
TALVTLTTQH VKYISDALRR LEEEEKVVEE EKQEHVEKVK DLLGWVSTLA
1410 1420 1430 1440 1450
RNTQGTTTSS HTSASADIEK AILEQQVLAE ELTTKKEQVS EAIKTSQIFL
1460 1470 1480 1490 1500
AKHGHKLSEG EKEQISEQLR VLNKTYHDLC DGSANQLQQL QSELAQQTEQ
1510 1520 1530 1540 1550
KTLQKQQDTC HKKLEDLCNW VGQAERALER HQGGASRQEL PALQQNQSDL
1560 1570 1580 1590 1600
KDLQGDIQSH STSFATAVKD IEGFLEENQT KLSPQELTAL REKLHQAKEQ
1610 1620 1630 1640 1650
YEVLQERTRV AQKELEEAVT SALQQETEKS KAATELAENK RKIDALLDWV
1660 1670 1680 1690 1700
ASVGSSERKP QASLPGMEQF SGACLEKQTL AATDGHVDVN QVPETLDRQY
1710 1720 1730 1740 1750
ELMKARHQEL LSQQQNFIVA TQSVQSFLDQ HSHNLTPEER QKLQEKLGEL
1760 1770 1780 1790 1800
KEQYAASLAR SEAELKQTQA LRDELQKFLQ DHKEFENWLQ QSENELDSMH
1810 1820 1830
KGGSSPEALN SLLKRQGSFS EDVISHKGDL RFVTISG
Length:1,837
Mass (Da):211,682
Last modified:July 27, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2FD07FD4EE55E3C9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 18 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9QXZ0MACF1_MOUSE
Microtubule-actin cross-linking fac...
Macf1 Acf7, Aclp7, Macf
7,354Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PVY8E9PVY8_MOUSE
Microtubule-actin cross-linking fac...
Macf1
7,355Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MQA6A0A0A0MQA6_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,328Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1ARU4B1ARU4_MOUSE
Microtubule-actin cross-linking fac...
Macf1
7,353Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7ACR9F7ACR9_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,333Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QA63E9QA63_MOUSE
Microtubule-actin cross-linking fac...
Macf1
7,351Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QNP1E9QNP1_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,478Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6Q750F6Q750_MOUSE
Microtubule-actin cross-linking fac...
Macf1
4,429Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1ARU1B1ARU1_MOUSE
Microtubule-actin cross-linking fac...
Macf1
5,895Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6YKN8F6YKN8_MOUSE
Microtubule-actin cross-linking fac...
Macf1
544Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1837Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL606918 Genomic DNA No translation available.
AL606932 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000147030; ENSMUSP00000123246; ENSMUSG00000028649

UCSC genome browser

More...
UCSCi
uc008upq.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606918 Genomic DNA No translation available.
AL606932 Genomic DNA No translation available.

3D structure databases

SMRiF6XCT0
ModBaseiSearch...

Proteomic databases

jPOSTiF6XCT0
MaxQBiF6XCT0
PeptideAtlasiF6XCT0
PRIDEiF6XCT0

Genome annotation databases

EnsembliENSMUST00000147030; ENSMUSP00000123246; ENSMUSG00000028649
UCSCiuc008upq.1 mouse

Organism-specific databases

MGIiMGI:108559 Macf1

Phylogenomic databases

eggNOGiKOG0516 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00940000155824

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Macf1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000028649 Expressed in 318 organ(s), highest expression level in lung
ExpressionAtlasiF6XCT0 baseline and differential

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR041615 Desmoplakin_SH3
IPR041573 Desmoplakin_Spectrin-like
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF17902 SH3_10, 1 hit
PF00435 Spectrin, 1 hit
PF18373 Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00150 SPEC, 6 hits
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6XCT0_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6XCT0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: December 11, 2019
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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