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Protein

BMP and activin membrane-bound inhibitor homolog

Gene

BAMBI

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Negatively regulates TGF-beta signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
BMP and activin membrane-bound inhibitor homologUniRule annotation
Gene namesi
Name:BAMBIImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 29

Organism-specific databases

VGNCiVGNC:15762 BAMBI

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei148 – 173HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500335032021 – 260BMP and activin membrane-bound inhibitor homologSequence analysisAdd BLAST240

Proteomic databases

PaxDbiF6X7H5

Expressioni

Gene expression databases

BgeeiENSECAG00000003193 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000002227

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili173 – 193Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the BAMBI family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIU1 Eukaryota
ENOG4110R2C LUCA
GeneTreeiENSGT00390000014168
InParanoidiF6X7H5
KOiK10162
OMAiVTGHENC
OrthoDBiEOG091G0PAE
TreeFamiTF333466

Family and domain databases

InterProiView protein in InterPro
IPR009345 BAMBI
PANTHERiPTHR15505:SF1 PTHR15505:SF1, 1 hit
PfamiView protein in Pfam
PF06211 BAMBI, 1 hit
PIRSFiPIRSF037456 BAMBI, 1 hit

Sequencei

Sequence statusi: Complete.

F6X7H5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRHSSYIFI WLQLELCAMA VLLTKGEIRC YCDAAHCVAT GYMCKSELSA
60 70 80 90 100
CFSRLLDPQN TNSPLTHGCL DSLASTADIC QAKQAHNHSG PTMPTLECCH
110 120 130 140 150
EDMCNYRGLH DVLSPPKGDT SGQRNRHQHD GSRNLITKVQ ELTSSKELWF
160 170 180 190 200
RAAVIAVPIA GGLILVLLIM LALRMLRSEN KRLHDQRQQM LSRLHYSFHG
210 220 230 240 250
HHSKKGQVAK LDLECMVPVS GHENCCLTCD KMRQADLSND KILSLVHWGM
260
YSGHGKLEFV
Length:260
Mass (Da):29,157
Last modified:July 27, 2011 - v1
Checksum:iAA7C92B2844F3C70
GO

Sequence databases

RefSeqiXP_001495085.3, XM_001495035.5

Genome annotation databases

EnsembliENSECAT00000003118; ENSECAP00000002227; ENSECAG00000003193
GeneIDi100063997
KEGGiecb:100063997

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_001495085.3, XM_001495035.5

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000002227

Proteomic databases

PaxDbiF6X7H5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSECAT00000003118; ENSECAP00000002227; ENSECAG00000003193
GeneIDi100063997
KEGGiecb:100063997

Organism-specific databases

CTDi25805
VGNCiVGNC:15762 BAMBI

Phylogenomic databases

eggNOGiENOG410IIU1 Eukaryota
ENOG4110R2C LUCA
GeneTreeiENSGT00390000014168
InParanoidiF6X7H5
KOiK10162
OMAiVTGHENC
OrthoDBiEOG091G0PAE
TreeFamiTF333466

Gene expression databases

BgeeiENSECAG00000003193 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

InterProiView protein in InterPro
IPR009345 BAMBI
PANTHERiPTHR15505:SF1 PTHR15505:SF1, 1 hit
PfamiView protein in Pfam
PF06211 BAMBI, 1 hit
PIRSFiPIRSF037456 BAMBI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6X7H5_HORSE
AccessioniPrimary (citable) accession number: F6X7H5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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