Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 70 (03 Jul 2019)
Sequence version 2 (10 Apr 2019)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

ATM serine/threonine kinase

Gene

ATM

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinasePROSITE-ProRule annotationSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ATM serine/threonine kinaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:15634 ATM

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6X5V1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000021147 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1961 – 2567FATInterPro annotationAdd BLAST607
Domaini2713 – 2956PI3K/PI4KInterPro annotationAdd BLAST244

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2578 – 2600DisorderedSequence analysisAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1612 – 1639Sequence analysisAdd BLAST28
Coiled coili3004 – 3024Sequence analysisAdd BLAST21

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0892 Eukaryota
ENOG410XNPY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00670000098061

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6X5V1

Identification of Orthologs from Complete Genome Data

More...
OMAi
LDPFPDH

TreeFam database of animal gene trees

More...
TreeFami
TF101182

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1070.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR015519 ATM/Tel1
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR021668 TAN

The PANTHER Classification System

More...
PANTHERi
PTHR11139:SF72 PTHR11139:SF72, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02259 FAT, 1 hit
PF00454 PI3_PI4_kinase, 1 hit
PF11640 TAN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00146 PI3Kc, 1 hit
SM01342 TAN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51189 FAT, 1 hit
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F6X5V1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLALNDLLI CCHQLGHDRA TERRKEVEKF KRLIRDPETV KQLDQHLDNK
60 70 80 90 100
QGKYLNWDAV FRFLQKYIQK EIEHLRTAKP NVSASTQAGR QKKMQEISSL
110 120 130 140 150
VKYFIKCANK RAPKLKCQEL LNYIMDTMKD SSNGAISGAD CSNILLKDIL
160 170 180 190 200
SVRKYWCEIS QQQWLELLSV YFRLYLKPSQ DINRVLVARI IQAVTKGCCS
210 220 230 240 250
QTDGLNSKFL EYFSKAIQHA RQEKSSAGLS HILAAFILFL KTLAVNFRIQ
260 270 280 290 300
VCELGDEILP TLLYVWTQHR LNDSLKEVMI ELFQLQIYIH HPKGAKTQEK
310 320 330 340 350
GAYESRKWKS ILYNLYDLLV NEISRIGSRG KYSSGSRNIA VKENLIELMA
360 370 380 390 400
DICHQVFSED TKSLEISQSY ATTQRECNDS SVSCKKRKIE LGWEVINDRL
410 420 430 440 450
QKSQNDFDLV PWLQIATQLI SKYPASLPNC ELSPLLMILC QLLPQQRRGE
460 470 480 490 500
RTPYVLRCLM EVALCQGKKS NLESSQKSDL LKLWNKIWCI TFRGISSEQI
510 520 530 540 550
QAENFGLLGA IIQGSLIEVD REFWKLFTGS ACKPSFPAVC CLTLALTICV
560 570 580 590 600
VPETVKTGME QNICEVNRSS SLKELIMKWL LFYQLEDDFE DSTELPPILH
610 620 630 640 650
SNFPHLALEK ILVSLTMKNC QAAMSFFQSV PECEKHQKDQ DEPSFSEVED
660 670 680 690 700
LFLQTTFDKM DFLTIGKEHA TEKHQPSIGF SVHQNLKESL NRCLLGLSEQ
710 720 730 740 750
LLNNYSSETT NSETLVRCSS LLVGVLGCYR YVGVIAEEEA YKSELFQKAK
760 770 780 790 800
SLMQCAGESI TLFKNKTNEE SRIVSLRNMM HLCTSCLCNC TKHSPNKIAS
810 820 830 840 850
GFFLRLLTSK LMNDIADICR SLASFTKKPF DYGEVESMRD DTDKNLMETE
860 870 880 890 900
DQSSMNLFDD CPTVSVGDAN ESGENQSTVG AINPLAEEHL SKQDLLFLDM
910 920 930 940 950
LKFLCMCVTS AQTNTVSFRA ADIRRKLLML LDSSMLDPAK SLHLHMYLVL
960 970 980 990 1000
LKELPGEEYS LPMEDVVELL KPLSNVCSFY RRDQDVCKTV LNHVLHVVMN
1010 1020 1030 1040 1050
LRQGNMDAEN TKDAQEQFLR VIEVFWRLTK EGKYAFSVRM ALVKCLKTLL
1060 1070 1080 1090 1100
EADPYSKWAI LKVKGNNFPV NEIFPQFLAD DHHQVRMLAA ESINRLFQDM
1110 1120 1130 1140 1150
EQGSSSRLLK ALPLKLQQTA FENAYLKAQE GMRQVSQRAE NPELLDDIYN
1160 1170 1180 1190 1200
RKAVLLMMIA VVLCCSPVCE KQALFALCKS VKDDGLEPHL VKKVLEKVSE
1210 1220 1230 1240 1250
TFGYRNLEDF MASHLDYLIL EWLNLRDNEY SLSSFPFILL NYANVEDFYR
1260 1270 1280 1290 1300
SCYKVLIPHL VIRSDFDEVK SIANQIQEDW KSLLTDCFPK ILVNILPYFA
1310 1320 1330 1340 1350
YEDTGDSGMA QQRETATKVY DMLKDENVLG KQIDHLFRSN LPEIVVELLM
1360 1370 1380 1390 1400
TLHEPATSGA SQSTDLCDFS GDLDPAPNPP HFPSHVIKAT FAYISSCHKT
1410 1420 1430 1440 1450
KLKSIVEILS KSPDSYQKIL LAICVQAAET NNIYKKHRIL KIYHLFVSLL
1460 1470 1480 1490 1500
LKDIKSGLGG AWAFVLRDVI YTLIHYINKR PSRFRDVSLR SFSLCCDLLS
1510 1520 1530 1540 1550
QVCHTAVTYC KDALESHLHV IVGTLIPLVD DQMEVQKQVL DLLKYLVIDN
1560 1570 1580 1590 1600
KDNENLYMTI KLLDPFPDHV VFKDLRITQQ KIKYSGGPFS LLEEINHFLS
1610 1620 1630 1640 1650
VSKYDALPLT RLEGLKDLRR QLEQHKDQMM DLMRASQDNP QGGIMVKLVV
1660 1670 1680 1690 1700
GLLQLSKMAI NHTGEREVLE AVGSCLGELG PIDFSTIAVQ HSKDTSYTKA
1710 1720 1730 1740 1750
LELFEDKELQ WTFIMLTYLN NTLVEDCVKV RSAAVTCLKN ILATKTGHSF
1760 1770 1780 1790 1800
WEIYKKTTDP MLIYLHPFRT SRKKFLEVPR IDKENPLEGL DDTSLWIPQS
1810 1820 1830 1840 1850
KNHDIWIKTL TCAVLDSGGT KSEILQLLKP MCEVKTDFCQ TVLPYLIHDI
1860 1870 1880 1890 1900
LLQDTNESWR NLLSTHIQGF FTNCFRHSSQ TSRSTTPANL DSESEHIFRG
1910 1920 1930 1940 1950
CLDKKSQRTM LAIVDYMRRQ KRPSSGTVFD EAFWLELNYL EVAKVAQSCA
1960 1970 1980 1990 2000
AHFTALLYAE IYADKKSMED QEKRSLTFEE GSQSTTISSL SEKSKEETGI
2010 2020 2030 2040 2050
SLQDLLLEIY RSIGEPDSLY GCGGGKMLQP LTRLRTYEHE AMWGKALVTY
2060 2070 2080 2090 2100
DLETAISSST RQAGIIQALQ NLGLCHILSV YLKGLDHENK EWCAELQELH
2110 2120 2130 2140 2150
YQAAWRNMQW DHCICVNKGA EGASYHKSLY NALQSLRDRE FSTFYESLKY
2160 2170 2180 2190 2200
ARVKEVEELC KGSLESVYSL YPTLSRLQTI GELENIGELF SRSVTDRQPS
2210 2220 2230 2240 2250
EVYIKWRKHS QLLKDSDFSF QEPIMALRTV ILEILMEKEM ESSQRQCFKD
2260 2270 2280 2290 2300
ILTKHLVELS TLARTFKNTQ LPERAIFQIK QYNSASCGVS EWQLEEAQVF
2310 2320 2330 2340 2350
WAKEEQSLAL SILKQMIKKL DASCTENDPN LKLMYTECLR ICGNWLAETC
2360 2370 2380 2390 2400
LENPAVIMQT YLEKAVEVAG NCDGESNDEL RNGKMKAFLS LARFSDTQYQ
2410 2420 2430 2440 2450
RIENYMKSSE FENKQALLKR AKEEVGLLRE HKIQTNRYTI KVQRELELDE
2460 2470 2480 2490 2500
CALRALKEDR KRFLCKAVEN YISCLLSGEG HDMWIFRLCS LWLENSGVSE
2510 2520 2530 2540 2550
VNGMMKRDGI KIPSYKFLPL MYQLAARMGT KMMGGLGFHE VLNNLISRIS
2560 2570 2580 2590 2600
MDHPHHTLFI ILALANANKD EFLTKPEAAR RSRITKSAPK QSSQLDEDRT
2610 2620 2630 2640 2650
EAANKIIHTI RTRRPQMIRS VEALCDAYII LANLDATQWR TQRQGINIPA
2660 2670 2680 2690 2700
DQPITKLQNL EDVVVPTMEI KVDPTGEYEN LVTIQSFKAE FRLAGGLNLP
2710 2720 2730 2740 2750
KIIDCLGSDG KERRQLVKGR DDLRQDAVMQ QVFQMCNTLL QRNTETRKRK
2760 2770 2780 2790 2800
LTICTYKVVP LSQRSGVLEW CTGTVPIGEF LVNNENGAHK RYRPEDFSAL
2810 2820 2830 2840 2850
QCQKKMMDVQ KKSFEEKYAT FMDICQNFQP VFRYFCMEKF LDPAVWFEKR
2860 2870 2880 2890 2900
LAYTRSVATS SIVGYILGLG DRHVQNILIN EQSAELVHID LGVAFEQGKI
2910 2920 2930 2940 2950
LPTPETVPFR LTRDIVDGMG ITGVEGVFRR CCEKTMEVMR NSQETLLTIV
2960 2970 2980 2990 3000
EVLLYDPLFD WTMNPLKALY LQQRPEDETE LHSTPHADDQ ECKRNLSDVD
3010 3020 3030 3040 3050
QSFNKVAERV LMRLQEKLKG VEEGTVLSVG GQISVIVRVG TILREKRVIS
3060 3070
WLQICFKSLQ CKTRWRSGFS
Length:3,070
Mass (Da):351,572
Last modified:April 10, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD28C9C6D46952F2D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2GU63A0A3Q2GU63_HORSE
Serine-protein kinase ATM
ATM
3,057Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HTF3A0A3Q2HTF3_HORSE
Serine-protein kinase ATM
ATM
3,046Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I0C9A0A3Q2I0C9_HORSE
Serine-protein kinase ATM
ATM
3,001Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GY53A0A3Q2GY53_HORSE
Serine-protein kinase ATM
ATM
3,076Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HJQ2A0A3Q2HJQ2_HORSE
Serine-protein kinase ATM
ATM
3,021Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6X5M9F6X5M9_HORSE
ATM serine/threonine kinase
ATM
3,034Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000023313; ENSECAP00000019300; ENSECAG00000021147

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PaxDbiF6X5V1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSECAT00000023313; ENSECAP00000019300; ENSECAG00000021147

Organism-specific databases

VGNCiVGNC:15634 ATM

Phylogenomic databases

eggNOGiKOG0892 Eukaryota
ENOG410XNPY LUCA
GeneTreeiENSGT00670000098061
InParanoidiF6X5V1
OMAiLDPFPDH
TreeFamiTF101182

Gene expression databases

BgeeiENSECAG00000021147 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

Gene3Di1.10.1070.11, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR015519 ATM/Tel1
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR021668 TAN
PANTHERiPTHR11139:SF72 PTHR11139:SF72, 1 hit
PfamiView protein in Pfam
PF02259 FAT, 1 hit
PF00454 PI3_PI4_kinase, 1 hit
PF11640 TAN, 1 hit
SMARTiView protein in SMART
SM00146 PI3Kc, 1 hit
SM01342 TAN, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51189 FAT, 1 hit
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6X5V1_HORSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6X5V1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: April 10, 2019
Last modified: July 3, 2019
This is version 70 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again