UniProtKB - F6X4S0 (F6X4S0_HORSE)
Protein
Submitted name:
Cortactin
Gene
CTTN
Organism
Equus caballus (Horse)
Status
Names & Taxonomyi
Protein namesi | Submitted name: CortactinImported |
Gene namesi | Name:CTTNImported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:16958, CTTN |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000021450, Expressed in oviduct epithelium and 23 other tissues |
ExpressionAtlasi | F6X4S0, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 453 – 511 | SH3InterPro annotationAdd BLAST | 59 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 50 | DisorderedSequence analysisAdd BLAST | 50 | |
Regioni | 71 – 90 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 254 – 281 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 298 – 408 | DisorderedSequence analysisAdd BLAST | 111 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 300 – 317 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 318 – 359 | PolyampholyteSequence analysisAdd BLAST | 42 |
Keywords - Domaini
SH3 domainPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000158565 |
InParanoidi | F6X4S0 |
TreeFami | TF318935 |
Family and domain databases
CDDi | cd11959, SH3_Cortactin, 1 hit |
InterProi | View protein in InterPro IPR015503, Cortactin IPR035716, Cortactin_SH3 IPR003134, Hs1_Cortactin IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR10829:SF15, PTHR10829:SF15, 3 hits |
Pfami | View protein in Pfam PF02218, HS1_rep, 6 hits PF14604, SH3_9, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51090, CORTACTIN, 6 hits PS50002, SH3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F6X4S0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MWKASAGHAV SLSQDDGGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ
60 70 80 90 100
EHINIHKLRE NVFQEHQTLK EKELETGPRA SHGYGGKFGV EQDRMDKSAV
110 120 130 140 150
GHEYQSKLSK HCSQVDSVRG FGGKFGVQVD RVDQSAVGFE YQGKTEKHAS
160 170 180 190 200
QKDYSSGFGG KYGVQADRVD KSAVGFDYQG KTEKHESQKD YSEGFGGKYG
210 220 230 240 250
IDKDKVDKSA VGFEYQGKTE KHESQTDYVK GFGGKFGVQT DRQDKCALGR
260 270 280 290 300
DHQEKLQLHE SQKDYSKGFG GKYGVQKDRM DKNASTFEDV AKVASTYQKT
310 320 330 340 350
VPVEAVNSKT SNIRANFENL AKEKEQEDRR KAEAERAQRM AKERQEQEEA
360 370 380 390 400
RRQLDEQARA RKQTPPASPA PQPVQERPPS SPVYEDAASF KAEPSYRGPV
410 420 430 440 450
SEPGPVYSTE AADYQDADSQ QGLAYAPEAV YESTEAQGHY PAEEGTYDEY
460 470 480 490 500
ENDLGITAIA LYDYQAAGDD EISFDPDDII TNIEMIDDGW WRGLCKGRYG
510
LFPANYVELR Q
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q2HJD2 | A0A3Q2HJD2_HORSE | Cortactin | CTTN | 559 | Annotation score: | ||
F6WKM3 | F6WKM3_HORSE | Cortactin | CTTN | 548 | Annotation score: | ||
A0A3Q2LRN5 | A0A3Q2LRN5_HORSE | Cortactin | CTTN | 528 | Annotation score: | ||
A0A3Q2H144 | A0A3Q2H144_HORSE | Cortactin | CTTN | 522 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000023332; ENSECAP00000019317; ENSECAG00000021450 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6X4S0 |
Genome annotation databases
Ensembli | ENSECAT00000023332; ENSECAP00000019317; ENSECAG00000021450 |
Organism-specific databases
VGNCi | VGNC:16958, CTTN |
Phylogenomic databases
GeneTreei | ENSGT00940000158565 |
InParanoidi | F6X4S0 |
TreeFami | TF318935 |
Gene expression databases
Bgeei | ENSECAG00000021450, Expressed in oviduct epithelium and 23 other tissues |
ExpressionAtlasi | F6X4S0, baseline |
Family and domain databases
CDDi | cd11959, SH3_Cortactin, 1 hit |
InterProi | View protein in InterPro IPR015503, Cortactin IPR035716, Cortactin_SH3 IPR003134, Hs1_Cortactin IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR10829:SF15, PTHR10829:SF15, 3 hits |
Pfami | View protein in Pfam PF02218, HS1_rep, 6 hits PF14604, SH3_9, 1 hit |
PRINTSi | PR00452, SH3DOMAIN |
SMARTi | View protein in SMART SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51090, CORTACTIN, 6 hits PS50002, SH3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6X4S0_HORSE | |
Accessioni | F6X4S0Primary (citable) accession number: F6X4S0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 59 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |