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UniProtKB - F6WXT2 (NU188_XENTR)

Entry version 52 (02 Dec 2020)
Sequence version 1 (27 Jul 2011)
Previous versions | rss
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Protein

Nucleoporin NUP188

Gene

nup188

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Required for proper protein transport into the nucleus.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-XTR-159227, Transport of the SLBP independent Mature mRNA
R-XTR-159230, Transport of the SLBP Dependant Mature mRNA
R-XTR-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-XTR-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript
R-XTR-191859, snRNP Assembly
R-XTR-3108214, SUMOylation of DNA damage response and repair proteins
R-XTR-3232142, SUMOylation of ubiquitinylation proteins
R-XTR-3301854, Nuclear Pore Complex (NPC) Disassembly
R-XTR-3371453, Regulation of HSF1-mediated heat shock response
R-XTR-4085377, SUMOylation of SUMOylation proteins
R-XTR-4551638, SUMOylation of chromatin organization proteins
R-XTR-4570464, SUMOylation of RNA binding proteins
R-XTR-4615885, SUMOylation of DNA replication proteins
R-XTR-5578749, Transcriptional regulation by small RNAs
R-XTR-9615933, Postmitotic nuclear pore complex (NPC) reformation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleoporin NUP188Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nup188
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...Xenbasei		XB-GENE-5933085, nup188

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nuclear pore complex, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Morpholino knockdown of the protein causes abnormal heart and gut looping.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004257952 – 1739Nucleoporin NUP188Add BLAST1738

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F6WXT2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in the developing kidney at stages 26-29 and 33-36, and in the branchial arches at stage 33-36.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSXETG00000012903, Expressed in gastrula and 37 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the nuclear pore complex (NPC).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		8364.ENSXETP00000028229

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Nup188 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4833, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002623_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F6WXT2

Identification of Orthologs from Complete Genome Data

More...OMAi		MENCFYV

Database of Orthologous Groups

More...OrthoDBi		79804at2759

TreeFam database of animal gene trees

More...TreeFami		TF101106

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024, ARM-type_fold
IPR018864, Nucleoporin_Nup188

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10487, Nup188, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

F6WXT2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAGCLYRR TSRELWTILL GRSSMKDGHQ IKAELDRYGD RLLQGLAYYR 
        60         70         80         90        100
PPSTSSTGKV KANKNLSPAL QELGLRLSKF LGLDEEQSVE LLQTYLLYDY 
       110        120        130        140        150
RGTQESVKGV PQDERQSQAL MLKASMVDYY YEERISLLRC VLYILNYFQD 
       160        170        180        190        200
DKHPYSAEFS KCVEMMEQKE LFGKYLKQFE SLCREEAPTW ETHGNFMTER 
       210        220        230        240        250
QVSRWFVQRL REQAMLLEII FLYFACFAAS PSDLLALTKL FKEQGFGCRL 
       260        270        280        290        300
QNRHLVEPSM DPLVERIGYF SVLIFLEALD IETLMTCSLS DKTEQHPFSS 
       310        320        330        340        350
EEQVCKEMDS VLVTLGDAPH HGPVLLAWAL LRFALNADKV TPTVRKMGST 
       360        370        380        390        400
AIQLHIFQYL TRMLQSLRSG ENNCTTSTAC LCVYTFLTFV LTNLEEQVLQ 
       410        420        430        440        450
SQQDLVDTAF QVFAAPNLPD LFWNMEPTAG LGILLDSVVG MFPFHLSPLL 
       460        470        480        490        500
KLFTALVSKS SAKKVYSFLD RMSSYTEHYR HKPHDILSHE DETLWKRQTP 
       510        520        530        540        550
KVLYALGLGQ TNLRIPQGTI GQVMADEHGF LVRWEYSYSC WTLFTCEIEM 
       560        570        580        590        600
LLHVVSTADV IHQCQRVKPI IDLVHKVIST DLSIADCLLP ITSRIYMLLQ 
       610        620        630        640        650
RLTTVMNPPM DFLSSCVDCL AALATRMPAK VWIDLRHTGF LPFAANPVSG 
       660        670        680        690        700
HIISTEGMNA GGYGSLFGIE QSQGEYSITL SFLRLVTTLV KGQLGSTQSQ 
       710        720        730        740        750
GLVPCILFVL REMLPNYHRW RYNSHGVREQ LGFQILSLIH AILNLSPEEE 
       760        770        780        790        800
ESTSTPNLQS LCIFSLTNTE AGQAVINIMG VGVDTLNAVM LTQAGSSGTE 
       810        820        830        840        850
GQGQMLMQTI KLAFSITNNV IRLKPLSSAI SPLEHALTQH GAHGNNLIAV 
       860        870        880        890        900
LAKYIYHKYD PSLPRLAIQL LKRLAMVAPM SVYACLGSDA AAIRDAFLSR 
       910        920        930        940        950
LRDNIEDMQI KIMILEFLTV AVETQPGLIE LFLNLEVKDT NEGSKEYSLG 
       960        970        980        990       1000
EWSCLQVVLK LIDSQDPESS WGAPLLHRSA IAFLHALWQD RRDSAMTVLR 
      1010       1020       1030       1040       1050
TKPNFWENLT SPLFGTLAFP SESSELSILE TCAFIMKIIC LEIYYAVRGS 
      1060       1070       1080       1090       1100
LGDSLKKILK KFSEEERFTY WSNYVHSLVC QVAESEGACN SLTEYQQLLS 
      1110       1120       1130       1140       1150
AWRMFLMVAT HNADVMHLTN PEVRQKLFKD VLGGTQALLL VPRSMTCLHL 
      1160       1170       1180       1190       1200
GSMLCTVMII LLRRWKSDLA APEDILSSLT QILEGVLQKD QQLVEKTKAR 
      1210       1220       1230       1240       1250
VFAALISALE IKPMKASEIP QYPQLVLNVC ETLQEEVVFL VDHTRQEVPA 
      1260       1270       1280       1290       1300
NDASEDKDSM ETEDTGRIRQ KDQRDGVCVL GLHLAKGLCE ADEEGDQWQQ 
      1310       1320       1330       1340       1350
VLRKLPVLPM LFSALEVSLR IKQNLHFCEA ILHFLFTLAK THQGAAAMAG 
      1360       1370       1380       1390       1400
AGVTQTVCLP LLSVYQLSSN GASTAQPALS LRKSLDAPSW PGVYRLTVSL 
      1410       1420       1430       1440       1450
MERLLKTLRY NFLTEALDFV GVHQERILQC LGAVRTVPSL ACLEEADHTV 
      1460       1470       1480       1490       1500
GFLLQLSNFT KEWHFHLPQL IKDVQVNLCY LCQACTSLLH SRKMLQHYLQ 
      1510       1520       1530       1540       1550
IKNGETMSST ATPRGQRTPQ TPSKQPTAES EALELRQLRS VQHSLLKILG 
      1560       1570       1580       1590       1600
KTLATLRAFT PDLCQILQPL DLAQYNLLFA LSFTTPAFDA DVTPSFGTLL 
      1610       1620       1630       1640       1650
ATVNVTLSML GEMDKKKDHP LGQVLGETNS TVDNKNIKSL LLFIMENCFY 
      1660       1670       1680       1690       1700
LLISQAVRYL RDPSVHPRDK QRMKQELSSE LSTLLSSLSR YFRRGGPSSP 
      1710       1720       1730 
AGGLMPSPQP KGASAAKVVP EAQEPLIQLV QAFVRHVQR
Length:1,739
Mass (Da):195,331
Last modified:July 27, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD712DA22F279D36D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5S6M1K6A0A5S6M1K6_XENTR
Nucleoporin NUP188 homolog
nup188
1,739Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8QJ76A0A6I8QJ76_XENTR
Nucleoporin NUP188 homolog
nup188
1,714Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SHX1A0A6I8SHX1_XENTR
Nucleoporin NUP188 homolog
nup188
1,688Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8S634A0A6I8S634_XENTR
Nucleoporin NUP188 homolog
nup188
1,643Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SNH5A0A6I8SNH5_XENTR
Nucleoporin NUP188 homolog
nup188
1,724Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti124 – 125Missing in AAI55687 (Ref. 2) Curated2
Sequence conflicti1568Q → QVQ in AAI55687 (Ref. 2) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAMC01047074 Genomic DNA No translation available.
BC155686 mRNA Translation: AAI55687.1

NCBI Reference Sequences

More...RefSeqi		NP_001107292.1, NM_001113820.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100135081

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		xtr:100135081

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01047074 Genomic DNA No translation available.
BC155686 mRNA Translation: AAI55687.1
RefSeqiNP_001107292.1, NM_001113820.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000028229

Proteomic databases

PaxDbiF6WXT2

Genome annotation databases

GeneIDi100135081
KEGGixtr:100135081

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23511
XenbaseiXB-GENE-5933085, nup188

Phylogenomic databases

eggNOGiKOG4833, Eukaryota
HOGENOMiCLU_002623_1_0_1
InParanoidiF6WXT2
OMAiMENCFYV
OrthoDBi79804at2759
TreeFamiTF101106

Enzyme and pathway databases

ReactomeiR-XTR-159227, Transport of the SLBP independent Mature mRNA
R-XTR-159230, Transport of the SLBP Dependant Mature mRNA
R-XTR-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-XTR-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript
R-XTR-191859, snRNP Assembly
R-XTR-3108214, SUMOylation of DNA damage response and repair proteins
R-XTR-3232142, SUMOylation of ubiquitinylation proteins
R-XTR-3301854, Nuclear Pore Complex (NPC) Disassembly
R-XTR-3371453, Regulation of HSF1-mediated heat shock response
R-XTR-4085377, SUMOylation of SUMOylation proteins
R-XTR-4551638, SUMOylation of chromatin organization proteins
R-XTR-4570464, SUMOylation of RNA binding proteins
R-XTR-4615885, SUMOylation of DNA replication proteins
R-XTR-5578749, Transcriptional regulation by small RNAs
R-XTR-9615933, Postmitotic nuclear pore complex (NPC) reformation

Gene expression databases

BgeeiENSXETG00000012903, Expressed in gastrula and 37 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR018864, Nucleoporin_Nup188
PfamiView protein in Pfam
PF10487, Nup188, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNU188_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6WXT2
Secondary accession number(s): A9JRJ6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 19, 2014
Last sequence update: July 27, 2011
Last modified: December 2, 2020
This is version 52 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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