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Entry version 37 (12 Aug 2020)
Sequence version 2 (10 Apr 2019)
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Protein

RRM domain-containing protein

Gene

RBM33

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RRM domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RBM33Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6WWS0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000022285, Expressed in inner cell mass and 22 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1109 – 1176RRMInterPro annotationAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 122DisorderedSequence analysisAdd BLAST122
Regioni185 – 221DisorderedSequence analysisAdd BLAST37
Regioni257 – 396DisorderedSequence analysisAdd BLAST140
Regioni413 – 718DisorderedSequence analysisAdd BLAST306
Regioni734 – 794DisorderedSequence analysisAdd BLAST61
Regioni839 – 873DisorderedSequence analysisAdd BLAST35
Regioni891 – 1025DisorderedSequence analysisAdd BLAST135

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi16 – 38PolyampholyteSequence analysisAdd BLAST23
Compositional biasi49 – 64PolyampholyteSequence analysisAdd BLAST16
Compositional biasi78 – 114PolarSequence analysisAdd BLAST37
Compositional biasi288 – 303PolyampholyteSequence analysisAdd BLAST16
Compositional biasi315 – 341Pro-richSequence analysisAdd BLAST27
Compositional biasi358 – 392Pro-richSequence analysisAdd BLAST35
Compositional biasi413 – 449Pro-richSequence analysisAdd BLAST37
Compositional biasi488 – 518Pro-richSequence analysisAdd BLAST31
Compositional biasi566 – 580Pro-richSequence analysisAdd BLAST15
Compositional biasi593 – 640Pro-richSequence analysisAdd BLAST48
Compositional biasi668 – 716PolarSequence analysisAdd BLAST49
Compositional biasi839 – 864PolarSequence analysisAdd BLAST26
Compositional biasi891 – 913PolarSequence analysisAdd BLAST23

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063891

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_051691_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6WWS0

TreeFam database of animal gene trees

More...
TreeFami
TF332363

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR039878, RBM33
IPR000504, RRM_dom

The PANTHER Classification System

More...
PANTHERi
PTHR22014, PTHR22014, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360, RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928, SSF54928, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6WWS0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAALGAGGG AGAGDDDFDQ FDKPGAERSW RRRAADEDWD SELEDDLLGE
60 70 80 90 100
DLLSGKKNQS DLSDEELNDD LLQSDNEDEE NFSSQGVTIS LNTTSGMVTS
110 120 130 140 150
FELSDNTNDQ SGEQESEYEQ GEDELVYHKS DGSELYAHEY PEEGQYEGHD
160 170 180 190 200
AELTEDHIEY VEEPEEEQLY NDEVLDIEIN EPLDEFTGGM ETLELQKDIK
210 220 230 240 250
EESDEEDDDD EESGRLRFKT ERKEGTIIRL SDVTRERRNI PETLELSAEA
260 270 280 290 300
KAALLEFEER ERQHKQGRYG SRRGGRRGGS LMCRGMGDQR RENSERGRMK
310 320 330 340 350
DHRPALLPTQ PPVVTHSPRL IPPPQPQPPP PPPPPPPQQQ PIRSLFQQQQ
360 370 380 390 400
LQPLLPLQHP HHPSPPQGMH MPPQIEAPRV MLTPPPVTPQ QPKNIHINPH
410 420 430 440 450
FKGAVVTPVQ VPLLPVPSQP RPAVGPQRFP GPPEFPQHTP GPVPNNFSQP
460 470 480 490 500
PRLPLQDQWR APPPPQDRDP FFLGVSGEPR FPSHLFLEQR SPPPPPPPPT
510 520 530 540 550
LLSSSHPVPT PSPLPFTQPG PAFNQQGQQP VFPRERPVRP ALQPPGPVGI
560 570 580 590 600
LHFSQPGSAA TRPFIPPRQP FLPGPGQPFL PAHAQPNLQA WKGPLHPPLP
610 620 630 640 650
PPHQPQPQPQ QQPPLQPQHQ PPLQPPPQHQ PPPPQPQHQP QHQPQHQHHH
660 670 680 690 700
HLSVPPPPLM PMAQPQFRPH MQTAQPQPNN GRMQCPQRQG LRHNTTSQNV
710 720 730 740 750
TKRPMQQMQP TAPRNSNLRE LPIAPSHVIE MSNSRCSSTP AAPVKPIIST
760 770 780 790 800
SPPTRPAVGS RSAQGKTEVK VKPLSPVVQP KEEVKAEPEF PDEDEETRLY
810 820 830 840 850
RLKIEEQKRL REEILKQKEL RRQQQAGARK KELLERLAQQ QQQLYPPSAP
860 870 880 890 900
AEQEEQTSSP SPTNGNPLLP FPGAQVRQNV KNRLLVKNQD VTVSNVQPKT
910 920 930 940 950
SSFVPSGANM QYQGQPMKPL KHLRQARTVP QSPAQHKVLQ GKPADGEGPP
960 970 980 990 1000
PPSQTPRVAS LQGRPLDAKP GTKRTVMHRA NSGGGDGPHV SSKVRVIKLS
1010 1020 1030 1040 1050
GGQGGESDGF FHPEGQPQRL PQPPEVRQQP ARKVTLTKGA LQPPQHPPVG
1060 1070 1080 1090 1100
AHVHSAGPPG IKSIQGIHPA KKVIMHGRGR GVAGAMGRGR LMPNKQNLRV
1110 1120 1130 1140 1150
VECKPQPCVV SVEGLSSSTT DVQLKSLLMS VGPIQSLQML PQQRKAIAKF
1160 1170 1180
KEPAHALAFQ QKFHRHMIDL SHINVALIVE
Length:1,180
Mass (Da):130,847
Last modified:April 10, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF3756EA5D3CD9663
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5F5PTN3A0A5F5PTN3_HORSE
Uncharacterized protein
RBM33
267Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000023754; ENSECAP00000019698; ENSECAG00000022285

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PaxDbiF6WWS0

Genome annotation databases

EnsembliENSECAT00000023754; ENSECAP00000019698; ENSECAG00000022285

Phylogenomic databases

GeneTreeiENSGT00530000063891
HOGENOMiCLU_051691_0_0_1
InParanoidiF6WWS0
TreeFamiTF332363

Gene expression databases

BgeeiENSECAG00000022285, Expressed in inner cell mass and 22 other tissues

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR039878, RBM33
IPR000504, RRM_dom
PANTHERiPTHR22014, PTHR22014, 1 hit
SMARTiView protein in SMART
SM00360, RRM, 1 hit
SUPFAMiSSF54928, SSF54928, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6WWS0_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6WWS0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: April 10, 2019
Last modified: August 12, 2020
This is version 37 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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