Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 68 (02 Jun 2021)
Sequence version 1 (27 Jul 2011)
Previous versions | rss
Add a publicationFeedback
Protein

Ubiquitinyl hydrolase 1

Gene

Usp34

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).ARBA annotation EC:3.4.19.12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseARBA annotation
Biological processUbl conjugation pathwayARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubiquitinyl hydrolase 1ARBA annotation (EC:3.4.19.12ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Usp34Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:109473, Usp34

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
F6WJB7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F6WJB7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
F6WJB7

PeptideAtlas

More...
PeptideAtlasi
F6WJB7

PRoteomics IDEntifications database

More...
PRIDEi
F6WJB7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
348821

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000056342, Expressed in primary oocyte and 310 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6WJB7, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1951 – 2296USPInterPro annotationAdd BLAST346

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni519 – 726DisorderedSequence analysisAdd BLAST208
Regioni795 – 825DisorderedSequence analysisAdd BLAST31
Regioni1516 – 1535DisorderedSequence analysisAdd BLAST20
Regioni3391 – 3504DisorderedSequence analysisAdd BLAST114

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2544 – 2564Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi536 – 558Polar residuesSequence analysisAdd BLAST23
Compositional biasi561 – 575Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi576 – 628Polar residuesSequence analysisAdd BLAST53
Compositional biasi637 – 673Acidic residuesSequence analysisAdd BLAST37
Compositional biasi701 – 721Polar residuesSequence analysisAdd BLAST21
Compositional biasi795 – 817Basic residuesSequence analysisAdd BLAST23
Compositional biasi3391 – 3430Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi3434 – 3466Polar residuesSequence analysisAdd BLAST33
Compositional biasi3486 – 3504Basic and acidic residuesSequence analysisAdd BLAST19

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase C19 family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158659

TreeFam database of animal gene trees

More...
TreeFami
TF323966

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR021905, DUF3517
IPR038765, Papain-like_cys_pep_sf
IPR001394, Peptidase_C19_UCH
IPR018200, USP_CS
IPR028889, USP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12030, DUF3517, 1 hit
PF00443, UCH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit
SSF54001, SSF54001, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00972, USP_1, 1 hit
PS00973, USP_2, 1 hit
PS50235, USP_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F6WJB7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XRSGSVSAIL SGGGGGGGRT MCENCADLVE VLNEISDIEG GDGLQLRKEH
60 70 80 90 100
TLKIFAYINS WTQRQCLCCF KEYKHLEIFN QVVCALINLV IAQVQVLRDQ
110 120 130 140 150
LCKHCTTINI DSTWQDESNQ AEEPLSIDRE CNEGNTERQK SIEKKSNSTR
160 170 180 190 200
TCNLTEEESS KSSDPFSLWN TDEKEKLLLC VAKIFQIQFP LYTAYKHNTH
210 220 230 240 250
PTIEDISTQE SNILGAFCDM NDVEVPLHLL RYVCLFCGKN GLSLMKDCFE
260 270 280 290 300
YGTPETLPFL IAHAFITVVS NIRIWLHIPA VMQHIIPFRT YVIRYLCKLS
310 320 330 340 350
DQELRQSAAR NMADLMWSTV KEPLDTTLCF DKESLDLAFK YFMSPTLTMR
360 370 380 390 400
LAGLSQITNQ LHTFNDVCNN ESLVSDTETS IAKELADWLI SNNVVEHIFG
410 420 430 440 450
PNLHIEIIKQ CQVILNFLAA EGRLSTQHID CIWAAAQLKH CSRYIHDLFP
460 470 480 490 500
SLIKNLDPVP LRHLLNLVSA LEPGVHTEQT LYLASMLIKA LWNNALAAKA
510 520 530 540 550
QLSKQSSFAS LLNTNMPIGN KKEEEELRRA APSPWSPAAS PQSSDNSDTH
560 570 580 590 600
QSGASDIEMD EQLINRNKHV QQRLSDTEES MQGSSDETAN SGEDGSSGPG
610 620 630 640 650
SSSGHSDGSS NEVNSSHASQ SAGSPGSEVQ SEDIADIEAL KEEEEEEEEE
660 670 680 690 700
EEEEEEEDDE EEEDEEEDDD DDDDHGHNPA KNTCGTELRN RKLENPAGIC
710 720 730 740 750
LGESQGTSER NGTNSGTGKD LVFNTEPLPS VDNRIRMLDA CAHSEDPEHG
760 770 780 790 800
ISGEVSSAHL AQGSQEACIT RSGDFLGETI GNELFNCRQF IGPQHHHHHH
810 820 830 840 850
HHHHHHHHHH HHHHHHHDGH MVDDMLSADD VSCSSSQVSA KSEKNMADFD
860 870 880 890 900
GEESGCEEEL VQINSHAELT SHLQQHLPNL ASIYHEHLSQ GPAVHKHQFS
910 920 930 940 950
SNAVTDINLD NVCKKGNTLL WDIVQDDDAI NLSEGLINEA EKLLCSLVCW
960 970 980 990 1000
FTDRQIRMRF IEGCLENLGN NRSVVISLRL LPKLFGTFQQ FGSSYDTHWI
1010 1020 1030 1040 1050
TMWAEKELNM MKLFFDNLVY YIQGIREGRQ KHALYSHSAE VQVRLQFLTC
1060 1070 1080 1090 1100
VFSTLGSPDH FRLSLEQVDI LWHCLVEDSE CYDDALHWFL NQVRSKDQHA
1110 1120 1130 1140 1150
MGMETYKHLF LEKMPQLKPE TISMTGLNLF QHLCNLARLA TSAYDGGSNS
1160 1170 1180 1190 1200
ELCGMDQFWG IALRAQSGDV SRAAIQYINS YYINGKTGLE KEQEFISKCM
1210 1220 1230 1240 1250
ESLMIASSSL EQESHSSLTV IERGLLMLKT HLEAFRRRFA YHLRQWQIEG
1260 1270 1280 1290 1300
TGISSHLKAL SDKQSLPLRV VCQPAGLPDK MTIEMYPSDQ VADLRAEVTH
1310 1320 1330 1340 1350
WYENLQKEQI NQQAQLQEFG QSSRKGEFPG GLMGPVRMIS SGHELTTDYD
1360 1370 1380 1390 1400
EKALHELGFK DMQMVFVSLG APRRERKGEG VQLPASCLPP PQKDNIPMLL
1410 1420 1430 1440 1450
LLQEPHLTTL FDLLEMLASF KPPSGKVAVD DSESLKCEEL HLHAENLSRR
1460 1470 1480 1490 1500
VWELLMLLPT CPNMLTAFQN VSDEQSNDGL NWKELLKIKS AHKLLYALEI
1510 1520 1530 1540 1550
IEALGKPNRR IRRESTGSYS DLYPDSDDSS EDQVENSKNS WTCKFVAAGG
1560 1570 1580 1590 1600
LQQLLEIFNS AILEPKEQES WTVWQLDCLA CLLKLICQFA VDPSDLDLAY
1610 1620 1630 1640 1650
HDVFAWSGIA ESHRKRTWPG KSRKAAGDHA KSLHIPRLTE VFLVLVQGTS
1660 1670 1680 1690 1700
LIQRLMSVAY TYDNLAPRVL KAQSDHRSRH EVSHYSMWLL VSWAHCCSLV
1710 1720 1730 1740 1750
KSSLADSDHL QDWLKQLTLL IPETAVRHES CNGLYKLSLS GLDGGDSIHR
1760 1770 1780 1790 1800
SFLLLAASTL LKFLPDAQAL KPPRIDDYEE EPLLKPGCKE YFWLLCKLVD
1810 1820 1830 1840 1850
NIHIKDASQT TLLDLDALAR HLADCIRSRE ILDHLDGSIE DDGLSGLLRL
1860 1870 1880 1890 1900
ATSVIKHKPP FKFSREGQEF LRDIFNLLFL LPSLKDRRQP KCKSHSCRAA
1910 1920 1930 1940 1950
AYDLLVEMVK GSVENYRLIH NWVMAQHMQS HAPYKWDYWP HEDVRAECRF
1960 1970 1980 1990 2000
VGLTNLGATC YLASTIQQLY MIPEARQAVF TAKYSEDMKH KTTLLELQKM
2010 2020 2030 2040 2050
FTYLMESECK AYNPRPFCKT YTMDKQPLNT GEQKDMTEFF TDLITKVEEM
2060 2070 2080 2090 2100
SPELKNTVKS LFGGVITNNV VSLDCEHVSQ TAEEFYTVRC QVADMKNIYE
2110 2120 2130 2140 2150
SLDEVTIKDT LEGDNMYTCS HCGKKVRAEK RACFKKLPRI LSFNTMRYTF
2160 2170 2180 2190 2200
NMVTMMKEKV NTHFSFPLRL DMTPYTEDFL MGKSDRKEGF KDVGDRSKDT
2210 2220 2230 2240 2250
ESYEYDLIGV TVHTGTADGG HYYSFIRDIV NPHAYKNNKW YLFNDAEVKP
2260 2270 2280 2290 2300
FDSAQLASEC FGGEMTTKTY DSVTDKFMDF SFEKTHSAYM LFYKRMEPEE
2310 2320 2330 2340 2350
ENGREYKFDV SSELLEWIWH DNMQFLQDKN IFEHTYFGFM WQLCSCIPST
2360 2370 2380 2390 2400
LPDPKAVSLM TAKLSTSFVL ETFIHSKEKP TMLQWIELLT KQFNNSQAAC
2410 2420 2430 2440 2450
EWFLDRMADD DWWPMQILIK CPNQIVRQMF QRLCIHVIQR LRPVHAHLYL
2460 2470 2480 2490 2500
QPGMEDGSDD MDASVEDIGG RSCVTRFVRT LLLIMEHGVK PHSKHLTEYF
2510 2520 2530 2540 2550
AFLYEFAKMG EEESQFLLSL QAISTMVHFY MGTKGPENPQ VEVLSEEEGE
2560 2570 2580 2590 2600
EEEEEEDILS LAEEKYRPAA LEKMIALVAL LVEQSRSERH LTLSQTDMAA
2610 2620 2630 2640 2650
LTGGKGFPFL FQHIRDGINI RQTCNLIFSL CRYNNRLAEH IVSMLFTSIA
2660 2670 2680 2690 2700
KLTPEAANPF FKLLTMLMEF AGGPPGMPPF ASYILQRIWE VIEYNPSQCL
2710 2720 2730 2740 2750
DWLAVQTPRN KLAHSWVLQN MENWVERFLL AHNYPRVRTS AAYLLVSLIP
2760 2770 2780 2790 2800
SNSFRQMFRS TRSLHIPTRD LPLSPDTTVV LHQVYNVLLG LLSRAKLYVD
2810 2820 2830 2840 2850
AAVHGTTKLV PYLSFMTYCL ISKTEKLMFS TYFMDLWNLF QPKLSEPAIA
2860 2870 2880 2890 2900
TNHNKQALLS FWYNVCADCP ENIRLIVQNP VVTKNIAFNY ILADHDDQDV
2910 2920 2930 2940 2950
VLFNRGMLPA YYGILRLCCE QSPAFTRQLA SHQNIQWAFK NLTPHASQYP
2960 2970 2980 2990 3000
GAVEELFNLM QLFIAQRPDM REEELEDIKQ FKKTTISCYL RCLDGRSCWT
3010 3020 3030 3040 3050
TLISAFRILL ESDEDRLLVV FNRGLILMTE SFNTLHMMYH EATACHVTGD
3060 3070 3080 3090 3100
LVELLSIFLS VLKSTRPYLQ RKDVKQALIQ WQERIEFAHK LLTLLNSYSP
3110 3120 3130 3140 3150
PELRNACIDV LKELVLLSPH DFLHTLVPFL QHNHCTYHHS NIPMSLGPYF
3160 3170 3180 3190 3200
PCRENIKLIG GKSNIRPPRP ELNMCLLPTM VETSKGKDDV YDRMLLDYFF
3210 3220 3230 3240 3250
SYHQFIHLLC RVAINCEKFT ETLVKLSVLV AYEGLPLHLA LFPKLWTELC
3260 3270 3280 3290 3300
QTQSAMSKNC IKLLCEDPVF AEYIKCILMD ERTFLNNNIV YTFMTHFLLK
3310 3320 3330 3340 3350
VQSQVFSEAN CASLISTLIT NLINQYQNLQ SDFTNRVEIS KASAALNGDL
3360 3370 3380 3390 3400
RALALLLSVH TPKQLNPALI PTLQELLNKC RTCLQQRNSL QEQEAKERKT
3410 3420 3430 3440 3450
KDDEGATPVK RRRVSSDEEH TVDSCIGDIK TETREVLTPT STSDNETRDS
3460 3470 3480 3490 3500
SIIDPGTEQD LPSPENSSVK EYRMEGPSSF SEDGSHIRSQ HAEEQSNNGR
3510 3520 3530 3540 3550
FDDCKEFKDH CSKDTTLAED ESEFPSTSIS AVLSDLADLR SCDGQALSSQ
3560 3570 3580 3590 3600
DPEAAVSLSC GHSRGLISHM QQHDILDTLC RTIESTIHVV TRISGKGNQA

AS
Length:3,602
Mass (Da):409,940
Last modified:July 27, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49666EFE586D717C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6ZQ93UBP34_MOUSE
Ubiquitin carboxyl-terminal hydrola...
Usp34 Kiaa0570, Murr2
3,582Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Z4YLQ1Z4YLQ1_MOUSE
Ubiquitin carboxyl-terminal hydrola...
Usp34
810Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Z4YN11Z4YN11_MOUSE
Ubiquitin carboxyl-terminal hydrola...
Usp34
288Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000137823; ENSMUSP00000120747; ENSMUSG00000056342

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

Proteomic databases

EPDiF6WJB7
jPOSTiF6WJB7
MaxQBiF6WJB7
PeptideAtlasiF6WJB7
PRIDEiF6WJB7
ProteomicsDBi348821

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
7689, 92 antibodies

Genome annotation databases

EnsembliENSMUST00000137823; ENSMUSP00000120747; ENSMUSG00000056342

Organism-specific databases

MGIiMGI:109473, Usp34

Phylogenomic databases

GeneTreeiENSGT00940000158659
TreeFamiTF323966

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Usp34, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000056342, Expressed in primary oocyte and 310 other tissues
ExpressionAtlasiF6WJB7, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR021905, DUF3517
IPR038765, Papain-like_cys_pep_sf
IPR001394, Peptidase_C19_UCH
IPR018200, USP_CS
IPR028889, USP_dom
PfamiView protein in Pfam
PF12030, DUF3517, 1 hit
PF00443, UCH, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
SSF54001, SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00972, USP_1, 1 hit
PS00973, USP_2, 1 hit
PS50235, USP_3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6WJB7_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6WJB7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again