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Protein
Submitted name:

GPI transamidase component PIG-T

Gene

PIGT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
GPI transamidase component PIG-TImported
Submitted name:
Phosphatidylinositol glycan, class T, isoform CRA_aImported
Gene namesi
Name:PIGTImported
ORF Names:hCG_38369Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000124155.16
HGNCiHGNC:14938 PIGT

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei332 – 353HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000124155

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501430363824 – 384Sequence analysisAdd BLAST361

Expressioni

Gene expression databases

BgeeiENSG00000124155 Expressed in 95 organ(s), highest expression level in heart

Structurei

3D structure databases

ProteinModelPortaliF6W983
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2407 Eukaryota
ENOG410XRR0 LUCA
HOVERGENiHBG049395

Family and domain databases

InterProiView protein in InterPro
IPR007245 PIG-T
PANTHERiPTHR12959 PTHR12959, 2 hits
PfamiView protein in Pfam
PF04113 Gpi16, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 42 potential isoforms that are computationally mapped.Show allAlign All

F6W983-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF
60 70 80 90 100
RTRWDSELQR EGDWSLFRMF SRTLTEPCPL ASESRVYVDI TTYNQDNETL
110 120 130 140 150
EVHPPPTTTY QDVILGTRKT YAIYDLLDTA MINNSRNLNI QLKWKRPPEN
160 170 180 190 200
EAPPVPFLHA QRYVSGYGLQ KGELSTLLYN THPYRAFPVL LLDTVPWYLR
210 220 230 240 250
LYVHTLTITS KGKENKPSYI HYQPAQDRLQ PHLLEMLIQL PANSVTKVSI
260 270 280 290 300
QFERALLKWT EYTPDPNHGF YVSPSVLSAL VPSMVAAKPV DWEESPLFNS
310 320 330 340 350
LFPVSDGSNY FVRLYTEPLL VNLPTPDFSM PYNVICLTCT VVAVCYGSFY
360 370 380
NLLTRTFHIE EPRTGGLAKR LANLIRRARG VPPL
Length:384
Mass (Da):43,616
Last modified:June 7, 2017 - v2
Checksum:iAC75FF3BD9DCB0C2
GO

Computationally mapped potential isoform sequencesi

There are 42 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q969N2PIGT_HUMAN
GPI transamidase component PIG-T
PIGT CGI-06, PSEC0163, UNQ716/PRO1379
578Annotation score:
A0A1W2PNP0A0A1W2PNP0_HUMAN
GPI transamidase component PIG-T
PIGT
580Annotation score:
A0A1W2PP53A0A1W2PP53_HUMAN
GPI transamidase component PIG-T
PIGT
441Annotation score:
B7Z7C5B7Z7C5_HUMAN
cDNA FLJ51130, highly similar to GP...
PIGT
123Annotation score:
H7C2Y2H7C2Y2_HUMAN
GPI transamidase component PIG-T
PIGT
275Annotation score:
A0A1W2PPQ7A0A1W2PPQ7_HUMAN
GPI transamidase component PIG-T
PIGT
393Annotation score:
A0A1W2PP57A0A1W2PP57_HUMAN
GPI transamidase component PIG-T
PIGT
495Annotation score:
A0A1W2PPS0A0A1W2PPS0_HUMAN
GPI transamidase component PIG-T
PIGT
505Annotation score:
A0A1W2PQ52A0A1W2PQ52_HUMAN
GPI transamidase component PIG-T
PIGT
318Annotation score:
A0A1W2PR92A0A1W2PR92_HUMAN
GPI transamidase component PIG-T
PIGT
432Annotation score:
There are more potential isoformsShow all

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021578 Genomic DNA No translation available.
AL031663 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75841.1
UniGeneiHs.437388

Genome annotation databases

EnsembliENST00000545755; ENSP00000443963; ENSG00000124155
UCSCiuc061xhz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021578 Genomic DNA No translation available.
AL031663 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75841.1
UniGeneiHs.437388

3D structure databases

ProteinModelPortaliF6W983
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000545755; ENSP00000443963; ENSG00000124155
UCSCiuc061xhz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000124155.16
HGNCiHGNC:14938 PIGT
OpenTargetsiENSG00000124155
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2407 Eukaryota
ENOG410XRR0 LUCA
HOVERGENiHBG049395

Miscellaneous databases

ChiTaRSiPIGT human

Gene expression databases

BgeeiENSG00000124155 Expressed in 95 organ(s), highest expression level in heart

Family and domain databases

InterProiView protein in InterPro
IPR007245 PIG-T
PANTHERiPTHR12959 PTHR12959, 2 hits
PfamiView protein in Pfam
PF04113 Gpi16, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6W983_HUMAN
AccessioniPrimary (citable) accession number: F6W983
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: June 7, 2017
Last modified: October 10, 2018
This is version 32 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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