UniProtKB - F6VZQ5 (F6VZQ5_HORSE)
Protein
Tetraspanin
Gene
TSPAN18
Organism
Equus caballus (Horse)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
Names & Taxonomyi
Protein namesi | Recommended name: TetraspaninUniRule annotation |
Gene namesi | Name:TSPAN18Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:24589, TSPAN18 |
Subcellular locationi
Other locations
- Membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 36 | HelicalUniRule annotationAdd BLAST | 25 | |
Transmembranei | 56 – 77 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 84 – 108 | HelicalUniRule annotationAdd BLAST | 25 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSECAG00000022867, Expressed in cerebellum and 18 other tissues |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 291 – 326 | DisorderedSequence analysisAdd BLAST | 36 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000157667 |
HOGENOMi | CLU_055524_4_1_1 |
InParanoidi | F6VZQ5 |
TreeFami | TF352892 |
Family and domain databases
Gene3Di | 1.10.1450.10, 1 hit |
InterProi | View protein in InterPro IPR000301, Tetraspanin IPR018499, Tetraspanin/Peripherin IPR018503, Tetraspanin_CS IPR008952, Tetraspanin_EC2_sf |
Pfami | View protein in Pfam PF00335, Tetraspanin, 1 hit |
PRINTSi | PR00259, TMFOUR |
SUPFAMi | SSF48652, SSF48652, 1 hit |
PROSITEi | View protein in PROSITE PS00421, TM4_1, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6VZQ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEGDCLSCMK YLLFVFNFFL FLGGACLLGI GIWVLVDPTG FREIVAANPL
60 70 80 90 100
LITGVYTLLA MGGLLFLLGF LGCCGAVREN KCLLLFFFLF ILIIFLAELS
110 120 130 140 150
AAILAFVFRE NLTREFFTKE LGKHYQGDND TDIFSATWNS VMITFGCCGV
160 170 180 190 200
NGPEDFKFAS VFRLLTLESA EVPEACCRRE PQTRGGVLLS REECLLGRDL
210 220 230 240 250
FLNKQGCYTV ILNAFETYVY LAGALAIGVL AIEVRKAPGP APPACLHLRA
260 270 280 290 300
LTQDQMAPHC GGYGVVSAAM SGCCLSIIMA LGAHPSKTLG AGGGRALRDG
310 320
HRPSSPTPHP LPPARPRVQS GPAWLT
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5Q244 | A0A5F5Q244_HORSE | Tetraspanin | TSPAN18 | 248 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000024514; ENSECAP00000020367; ENSECAG00000022867 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6VZQ5 |
Genome annotation databases
Ensembli | ENSECAT00000024514; ENSECAP00000020367; ENSECAG00000022867 |
Organism-specific databases
VGNCi | VGNC:24589, TSPAN18 |
Phylogenomic databases
GeneTreei | ENSGT00940000157667 |
HOGENOMi | CLU_055524_4_1_1 |
InParanoidi | F6VZQ5 |
TreeFami | TF352892 |
Gene expression databases
Bgeei | ENSECAG00000022867, Expressed in cerebellum and 18 other tissues |
Family and domain databases
Gene3Di | 1.10.1450.10, 1 hit |
InterProi | View protein in InterPro IPR000301, Tetraspanin IPR018499, Tetraspanin/Peripherin IPR018503, Tetraspanin_CS IPR008952, Tetraspanin_EC2_sf |
Pfami | View protein in Pfam PF00335, Tetraspanin, 1 hit |
PRINTSi | PR00259, TMFOUR |
SUPFAMi | SSF48652, SSF48652, 1 hit |
PROSITEi | View protein in PROSITE PS00421, TM4_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6VZQ5_HORSE | |
Accessioni | F6VZQ5Primary (citable) accession number: F6VZQ5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | December 2, 2020 | |
This is version 50 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |