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UniProtKB - F6VYE2 (F6VYE2_MOUSE)

Entry version 44 (26 Feb 2020)
Sequence version 1 (27 Jul 2011)
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Protein
Submitted name:

Zinc finger MYM-type protein 4

Gene

Zmym4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Zinc finger MYM-type protein 4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zmym4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1915035 Zmym4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		F6VYE2

PeptideAtlas

More...PeptideAtlasi		F6VYE2

PRoteomics IDEntifications database

More...PRIDEi		F6VYE2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000042446 Expressed in embryonic stem cell and 283 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F6VYE2 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini90 – 126TRASHInterPro annotationAdd BLAST37
Domaini138 – 178TRASHInterPro annotationAdd BLAST41
Domaini190 – 228TRASHInterPro annotationAdd BLAST39
Domaini235 – 274TRASHInterPro annotationAdd BLAST40
Domaini347 – 383TRASHInterPro annotationAdd BLAST37
Domaini389 – 424TRASHInterPro annotationAdd BLAST36
Domaini432 – 470TRASHInterPro annotationAdd BLAST39
Domaini476 – 511TRASHInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 40DisorderedSequence analysisAdd BLAST40
Regioni714 – 742DisorderedSequence analysisAdd BLAST29
Regioni784 – 845DisorderedSequence analysisAdd BLAST62

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi819 – 839BasicSequence analysisAdd BLAST21

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159550

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004099_1_1_1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR021893 DUF3504
IPR011017 TRASH_dom
IPR010507 Znf_MYM

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12012 DUF3504, 1 hit
PF06467 zf-FCS, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00746 TRASH, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6VYE2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XPLDDEYDRA VAPQQGLLDR VKDEPDNAQE YSHGQQQKTQ EGELKISAVF 
        60         70         80         90        100
SVSGSPLAPQ LTTGFQPSLA SPGMNKMLPS VPATAVRVSC SGCKKILQKG 
       110        120        130        140        150
QTAYQRKGST QLFCSTLCLT GYTVPPARPP PPLTKKTCSS CSKDILNPKD 
       160        170        180        190        200
VISAQFENST TSKDFCSQSC LSTYELKKKP IVTINTNSIS TKCSMCQKNA 
       210        220        230        240        250
VIRHEVNYQN VVHKLCSDAC FSKFRSANNL TMNCCENCGG YCYSGSGQCH 
       260        270        280        290        300
VLQIEGQSKK FCSSMCVTSY KQNLFNKPTG MNSSVVPLSQ GQVIVSIPTG 
       310        320        330        340        350
SSASAGGGST PAVSPTSINS SAAAGLQRLA AQSQHVGFAR SVVKLRCQHC 
       360        370        380        390        400
NRLFATKPEL LDYKGKMFQF CGKNCCDEYK KINNVMAMCE YCKIEKIIKE 
       410        420        430        440        450
TVRFSGADKS FCSEGCKLLY KHDLGKRWGS HCKMCSYCLQ TSPKLIQNNL 
       460        470        480        490        500
GGKVEDFCCE ECMSKYTVLF YQMAKCDGCK RQGKLSESLK WRGDIKHFCN 
       510        520        530        540        550
LLCILMFCHQ QTVCDPPLQN NAVASISMVQ AASAGPPSLR KDSTPVIANV 
       560        570        580        590        600
VSLASAPAAQ PTANTNSVLQ GAVPTVTAKI IGDASTQTDA LKLPPSQPPR 
       610        620        630        640        650
LLKNKALLCK PITQTKATSC KPHTQNKECQ TDTPSEPQVM VVPVPVPVFV 
       660        670        680        690        700
PIPLHLYTQY TPVPFGIPVP MPVPMFIPSS MDNDEKATEG IEDIKEKLAT 
       710        720        730        740        750
HPFEADLLEM AEMIAEDEEK EKTLSQGESQ TSEQELFLDT KIFEKDQGST 
       760        770        780        790        800
YSGDLESEAV STPHSWEEEL NHYALKSNAV QDADSELKPF SKGETEQDLE 
       810        820        830        840        850
ADFPSESFDP LNKGQGIQAR SRTRRRHRDG FPQPRRRGRK KSVVPVEPRS 
       860        870        880        890        900
LIQGALQGCS VSGMTLKYMY GVNAWKNWVQ WKNAKDEQGD LKCGGGELAS 
       910        920        930        940        950
ASPCSDSLGS AQDHALSQES SEQGCKARSV KLKEDILSCT FSELSLGLCQ 
       960        970        980        990       1000
FIQEVRRPNG EKYDPDSILY LCLGIQQYLF ENGRIDNIFT EPYSRFMIEL 
      1010       1020       1030       1040       1050
TKLLKIWEPT ILPNGYMFSR IEEEHLWECK QLGAYSPIVL LNTLLFFNTK 
      1060       1070       1080       1090       1100
YFQLRNVTEH LKLSFAHVMR RTRTLKYSTK MTYLRFFPPL QKPESEPDKV 
      1110       1120       1130       1140       1150
TIGKRKRNED DEAPVGVEMA ENTDNPLRCP VRLYEFYLSK CSESVKQRSD 
      1160       1170       1180       1190       1200
VFYLQPERSC VPNSPMWYST FPIDPGTLDT MLTRILMVRE VHEELAKAKS 

EDSDAELSD
Length:1,209
Mass (Da):134,317
Last modified:July 27, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C3650649174C194
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2A791ZMYM4_MOUSE
Zinc finger MYM-type protein 4
Zmym4 Kiaa0425, Zfp262, Znf262
1,549Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL606908 Genomic DNA No translation available.
AL606985 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000135003; ENSMUSP00000120813; ENSMUSG00000042446

UCSC genome browser

More...UCSCi		uc012dli.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL606908 Genomic DNA No translation available.
AL606985 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

Proteomic databases

MaxQBiF6VYE2
PeptideAtlasiF6VYE2
PRIDEiF6VYE2

Genome annotation databases

EnsembliENSMUST00000135003; ENSMUSP00000120813; ENSMUSG00000042446
UCSCiuc012dli.2 mouse

Organism-specific databases

MGIiMGI:1915035 Zmym4

Phylogenomic databases

GeneTreeiENSGT00940000159550
HOGENOMiCLU_004099_1_1_1

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Zmym4 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000042446 Expressed in embryonic stem cell and 283 other tissues
ExpressionAtlasiF6VYE2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR021893 DUF3504
IPR011017 TRASH_dom
IPR010507 Znf_MYM
PfamiView protein in Pfam
PF12012 DUF3504, 1 hit
PF06467 zf-FCS, 5 hits
SMARTiView protein in SMART
SM00746 TRASH, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6VYE2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6VYE2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: February 26, 2020
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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