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Protein
Submitted name:

Neuronal guanine nucleotide exchange factor

Gene

NGEF

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal guanine nucleotide exchange factorImported
Gene namesi
Name:NGEFImported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 12

Expressioni

Gene expression databases

BgeeiENSMMUG00000012216

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000016020

Structurei

3D structure databases

ProteinModelPortaliF6VMG6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini275 – 459DHInterPro annotationAdd BLAST185
Domaini491 – 603PHInterPro annotationAdd BLAST113
Domaini614 – 675SH3InterPro annotationAdd BLAST62

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili379 – 399Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3523 Eukaryota
COG5422 LUCA
GeneTreeiENSGT00550000074493
InParanoidiF6VMG6
KOiK07525
OMAiGWIFGER
OrthoDBiEOG091G04NI
TreeFamiTF316357

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
cd11939 SH3_ephexin1, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR035635 Ephexin-1_SH3
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00621 RhoGEF, 1 hit
PF00018 SH3_1, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

F6VMG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKESEDLE KTQRKSRVIS ASDQQNIDNE PVEVKPELLP EKETSQADQD
60 70 80 90 100
IQDKEPHSHS PIKRNSIFNR SIRRRSKAKA RDTPERNASC LADSQDNGKS
110 120 130 140 150
VNESLTLNIP CSRMPPWRTA VQTGPGAQKM SESSSTPGNG ATPEEWPALA
160 170 180 190 200
DSPTTLTEAL RMIHPIPADS WRNLIEQIGL LYQEYRDKST LQEIETRRQQ
210 220 230 240 250
DAEIEDNTNG SPASEDTPEE EEEEEEEEPA SPPERKALPQ ICLLSNPHSR
260 270 280 290 300
FNLWQDLPEI RSSGVLEILQ PEEIKLQEAM FELVTSEASY YKSLNLLVSH
310 320 330 340 350
FMENERMRKI LHPSEAHILF SNVLDVLAVS ERFLLELEHR MEENIVISDV
360 370 380 390 400
CDIVYRYAAD HFSVYITYVS NQTYQERAYK QLLQEKAAFR ELISQLELDP
410 420 430 440 450
KCKGLPFSSF LILPFQRITR LKLLVQNILK RVEERSEREC TALDAHKELE
460 470 480 490 500
MVVKACNEGV RKMSRTEQMI CIQKKMEFKI KSVPIISHSR WLLKQGELQQ
510 520 530 540 550
MSGPKTSRTL RTKKLFHEIY LFLFNDLLVI CRQIPGDKYQ VFDSAPRGLL
560 570 580 590 600
RVEELEDQGQ TLANVFILRL LENADDREAT YMLKASSQSE MKRWMTSLAP
610 620 630 640 650
NRRTKFVSFT SRLLDCPQVQ CVHPYVAQQP DELTLELADI LNILDKTDDG
660 670 680 690 700
WIFGERLHDQ ERGWFPSSMT EEILNPKIRS QNLKECFRVH KMDDPQRSQN
710
KDRRKLGSRN RQ
Length:712
Mass (Da):82,454
Last modified:July 27, 2011 - v1
Checksum:i29CD66A154FE26C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03009866 Genomic DNA No translation available.
RefSeqiXP_001114604.1, XM_001114604.3
UniGeneiMmu.4419

Genome annotation databases

EnsembliENSMMUT00000017106; ENSMMUP00000016020; ENSMMUG00000012216
GeneIDi713917
KEGGimcc:713917

Similar proteinsi

Entry informationi

Entry nameiF6VMG6_MACMU
AccessioniPrimary (citable) accession number: F6VMG6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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