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Protein

Matrix metalloproteinase

Gene

MMP1

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Ca2+UniRule annotation
  • Zn2+UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotationSAAS annotation, Protease
LigandCalciumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiM10.001

Names & Taxonomyi

Protein namesi
Recommended name:
Matrix metalloproteinaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:MMP1Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation, ZymogenUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000025952

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M10A family.UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1565 Eukaryota
ENOG410XQ5D LUCA
GeneTreeiENSGT00760000118870
InParanoidiF6VC12
OMAiFHGTRQY
OrthoDBiEOG091G03DP
TreeFamiTF315428

Family and domain databases

CDDicd00094 HX, 1 hit
cd04278 ZnMc_MMP, 1 hit
Gene3Di1.10.101.10, 1 hit
2.110.10.10, 1 hit
3.40.390.10, 2 hits
InterProiView protein in InterPro
IPR000585 Hemopexin-like_dom
IPR036375 Hemopexin-like_dom_sf
IPR018487 Hemopexin-like_repeat
IPR018486 Hemopexin_CS
IPR033739 M10A_MMP
IPR024079 MetalloPept_cat_dom_sf
IPR001818 Pept_M10_metallopeptidase
IPR021190 Pept_M10A
IPR021158 Pept_M10A_Zn_BS
IPR006026 Peptidase_Metallo
IPR002477 Peptidoglycan-bd-like
IPR036365 PGBD-like_sf
IPR036366 PGBDSf
PfamiView protein in Pfam
PF00045 Hemopexin, 4 hits
PF00413 Peptidase_M10, 1 hit
PF01471 PG_binding_1, 1 hit
PIRSFiPIRSF001191 Peptidase_M10A_matrix, 1 hit
PRINTSiPR00138 MATRIXIN
SMARTiView protein in SMART
SM00120 HX, 4 hits
SM00235 ZnMc, 1 hit
SUPFAMiSSF47090 SSF47090, 1 hit
SSF50923 SSF50923, 1 hit
PROSITEiView protein in PROSITE
PS00546 CYSTEINE_SWITCH, 1 hit
PS00024 HEMOPEXIN, 1 hit
PS51642 HEMOPEXIN_2, 4 hits

Sequencei

Sequence statusi: Complete.

F6VC12-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSCPPPLLL LLLFWAVVSH GFPATLETQE PDVEIVQKYL ERYYNLRNDG
60 70 80 90 100
KLVEKQRNSG PVVEKLKQMQ EFFGLKVTGK PDAETLHVMK QPRCGVPDVA
110 120 130 140 150
RFVLTEGNPR WEKTHLTYRI ENYTPDLPRA DVDHAIEKAF QLWSNVTPLT
160 170 180 190 200
FTKVPKGQAD IMISFVRGDH RDNSPFDGPG GNLAHAFQPG PGIGGDAHFD
210 220 230 240 250
EDEMWTNNFR EYNLYRVAAH ELGHSLGLSH STDIGALMFP SYTFSGDVQL
260 270 280 290 300
AQDDINGIQA IYGRSQNPVQ PTGPQTPQVC DSKLTFDAVT TLRGEVMFFK
310 320 330 340 350
DRFYMRTNPF YPEVELNFIS VFWPQLPNGL EAAYEFADRD EVRFFKGNKY
360 370 380 390 400
WAVQGQNVLH GYPKDIYSSF GFPRTVKHID AALSEENTGK TYFFVGNKYW
410 420 430 440 450
RYDEYKRSMD AGYPKMIAHD FPGIGHKVDA VFMKDGFFYF FHGTRQYKFD
460 470
PKTKRILTLQ KANSWFNCRK N
Length:471
Mass (Da):54,077
Last modified:June 20, 2018 - v2
Checksum:iD1676E6D32D7A05C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01009240 mRNA Translation: JAB02621.1

Genome annotation databases

EnsembliENSCJAT00000027425; ENSCJAP00000025952; ENSCJAG00000014107

Similar proteinsi

Entry informationi

Entry nameiF6VC12_CALJA
AccessioniPrimary (citable) accession number: F6VC12
Secondary accession number(s): U3CMY2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: June 20, 2018
Last modified: June 20, 2018
This is version 55 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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