UniProtKB - F6V6B4 (F6V6B4_HORSE)
Protein
Submitted name:
Zinc finger protein 554
Gene
ZNF554
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- negative regulation of transcription by RNA polymerase II Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 554Imported |
Gene namesi | Name:ZNF554Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:25341, ZNF554 |
Subcellular locationi
Nucleus
- nuclear chromatin Source: GO_Central
- nucleolus Source: Ensembl
- nucleoplasm Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSECAG00000019482, Expressed in muscle tissue and 23 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 89 | KRABInterPro annotationAdd BLAST | 89 | |
Domaini | 212 – 241 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 270 – 297 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 298 – 325 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 326 – 353 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 354 – 381 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 382 – 409 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 410 – 437 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 438 – 465 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 220 – 249 | DisorderedSequence analysisAdd BLAST | 30 |
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000163560 |
HOGENOMi | CLU_002678_0_9_1 |
InParanoidi | F6V6B4 |
TreeFami | TF337055 |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 7 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 5 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 8 hits |
i Sequence
Sequence statusi: Complete.
F6V6B4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
ELLAPAQRTL YREVMLETCR NLASLEALKN LIPESGAEDG TSSPAQTSRV
60 70 80 90 100
TSLSPWTTYS LFQPVVSFHL EQGEAMWMGE KGIPQASCPG WENRPENHES
110 120 130 140 150
IYKKVVWREE PPGGMNIIKL PREGWGCGRL EENQEDPQRL LRRMAYIHVK
160 170 180 190 200
AFAQESATAQ YEFGENYNRS SDPVLSQGGS VGKHFHNCDL DIENLVADPF
210 220 230 240 250
LNHPQTGYTD RRSCESNECG KDLGQNSPVI QHKRTQRGEK TSAYEESGKP
260 270 280 290 300
FNRGMALTIH NKINTVEKPF ECRQCGKVFN RRHSLSEHQR IHTGERPYEC
310 320 330 340 350
QECGRAFTHS STLTRHLRTH TGEKPYACSE CGKAFNRISS LTQHQRIHTG
360 370 380 390 400
EKPYKCEDCG KSFCQSSYLI LHKRTHTGEK PYECHECGKA FSDRSSLNQH
410 420 430 440 450
ERTHTGENPY DCRQCGRAFS QRSSLVRHER THTGEKPYSC NECGKAFSQS
460 470 480
SSLVTHQKTH TSQKTYKMID CGKAFYQSSH LIGF
Genome annotation databases
Ensembli | ENSECAT00000020622; ENSECAP00000016936; ENSECAG00000019482 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6V6B4 |
Genome annotation databases
Ensembli | ENSECAT00000020622; ENSECAP00000016936; ENSECAG00000019482 |
Organism-specific databases
VGNCi | VGNC:25341, ZNF554 |
Phylogenomic databases
GeneTreei | ENSGT00940000163560 |
HOGENOMi | CLU_002678_0_9_1 |
InParanoidi | F6V6B4 |
TreeFami | TF337055 |
Gene expression databases
Bgeei | ENSECAG00000019482, Expressed in muscle tissue and 23 other tissues |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 7 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 5 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 8 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6V6B4_HORSE | |
Accessioni | F6V6B4Primary (citable) accession number: F6V6B4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | December 2, 2020 | |
This is version 61 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |