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Entry version 35 (05 Jun 2019)
Sequence version 1 (27 Jul 2011)
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Protein
Submitted name:

BCL6 corepressor

Gene

bcor

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
BCL6 corepressorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:bcorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-1010841 bcor

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000015528 Expressed in 13 organ(s), highest expression level in blastula

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6URS9 baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1327 – 1431ANK_REP_REGIONInterPro annotationAdd BLAST105
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1362 – 1394ANKPROSITE-ProRule annotationAdd BLAST33
Repeati1395 – 1427ANKPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni329 – 370DisorderedSequence analysisAdd BLAST42
Regioni521 – 544DisorderedSequence analysisAdd BLAST24
Regioni646 – 682DisorderedSequence analysisAdd BLAST37
Regioni1130 – 1316DisorderedSequence analysisAdd BLAST187

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi653 – 677PolyampholyteSequence analysisAdd BLAST25
Compositional biasi1130 – 1147PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1173 – 1193PolarSequence analysisAdd BLAST21
Compositional biasi1223 – 1240PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1248 – 1279PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1280 – 1310PolarSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHDH Eukaryota
ENOG410YT00 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153737

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit
3.10.260.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR031628 BCOR
IPR032365 PUFD
IPR038227 PUFD_som_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit
PF15808 BCOR, 1 hit
PF16553 PUFD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6URS9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRTGLMQEG MRVPSGMVYP SLCGLGSEKV REPSGTIPGL GYVSDRNPDL
60 70 80 90 100
QYKPTAAETM DNSHMSMKQS NGFNPLFKTP PGLQKAPVPT SESLVMDRSA
110 120 130 140 150
SDKQNPLSVN GANYLRIPWM NPYMESTSPA MYPFIDSPNK YSLNMYKAFL
160 170 180 190 200
PQQSAYSIPQ HLAYSPVCPN GERFVYIPPS HYVGPHIASG LAPSIKIPPP
210 220 230 240 250
SATPAIPTSV HCLEKNLPWK MGVSPGSAVD SHAYSHLPNS KQPRVTCVKS
260 270 280 290 300
TTGNISPEPA LLLNPSQRPS SRLHCPVQQV GDSFSEFQTP FAKIPTPPTS
310 320 330 340 350
IVHSKPLCNV SNDFTPLRIP NIKVHKNHEP EIAQVQAPLK KNRDRKESKS
360 370 380 390 400
PVLVQKQMPH KDGGEKPLDL SSKFGDADIS KVECTENAPS ILHLASHVNT
410 420 430 440 450
MGLSSRDAHK EAISPPTNSS GIVRPEIIST AASSWVVPGI THTEETNGII
460 470 480 490 500
MSLKNKTLER VMPQQRSSSC PRMGSSESVV CSNPGIVPAM GRPASASPAP
510 520 530 540 550
NANAEVRNPE DCNKSVIQQV PTSVSTSVKN SRAVKSSVPE STMKVNENSM
560 570 580 590 600
PPAAPMFVHQ SEPFCSPPLA YPSSFIPYQV SETLALSHLH LHNKAPVYPH
610 620 630 640 650
PVLLSNGSLF PGPMAPKPGI PYSMPTNRDY MTYQDTLGMV HPILLPPTTI
660 670 680 690 700
EMSKDGQERR SRSHERPRYD DSPPRSRLLD ISDSSSKLSF EIPADKALKV
710 720 730 740 750
HHGSRHVSKP EKLSTNAERD AKCNTNLAVK LKTNDVTVEK PEQGLQNRDL
760 770 780 790 800
ITREEIQRTN EFHRSFQVSR PTLESPVFHY RQESPLGNQN ADCSAAEACA
810 820 830 840 850
RFLAPPESND VPVGHFSRGQ EKSQPFLGSN GHSDIEMIDS LGRDAADEFE
860 870 880 890 900
TINGKLVKTK SSKLTKRIAN SAGYVGDRFK CVTTELYADS SQLSREQRAL
910 920 930 940 950
QIEGLEEDSI LSPPAAYCER AMMRFSELEM KAQEEHMPSK DSESCKNVTE
960 970 980 990 1000
WEELKPAVAK PVVEHSGNIQ MEGLEKSTLV NMDEIAKYPE REYLKRDCHF
1010 1020 1030 1040 1050
ERMNLYEEAV LPTDNFSQRH CLSIKRKHPE DIQPEEFLHS LTTEEALREE
1060 1070 1080 1090 1100
TQAKRKKIDD YCGNDLVDCS SKALAESHSN EVTNLKVCIE LTGLHPKKQR
1110 1120 1130 1140 1150
HLQHLRELGQ QCRRDSSEIR VVSETENKLR PWEEEQSIKK KPESKCTSGL
1160 1170 1180 1190 1200
ESIKTDIPEE DTSVPLHPKG FTSGCPSSKQ QNQTHSTLVP RLGSKQQKIR
1210 1220 1230 1240 1250
DGRKSNVQNA DEEGGLQDTS LLEDYTDCEK PSGKRQCKTK HLAPQERRRK
1260 1270 1280 1290 1300
KLSVSGDDST DEKVVLRGHK KHAEGSSDDS PVKTQEQMAP AIQTPSLSLP
1310 1320 1330 1340 1350
LPNTVQEATP SRPMPPEARR LIVNKNAGET LLQRAAHLYS TKEVVLYCLE
1360 1370 1380 1390 1400
SKSCDVNHRD NAGYCALHEA CARGWLSIVR HLLEHGADVN CSAQDGTRPI
1410 1420 1430 1440 1450
HDAVENDHLE IVRLLLSYGA DPTLATYSGR TIAKMTHSEA METFLTEYLT
1460 1470 1480 1490 1500
DLQGRSCDDP GLSWDFYGSS VCDLKEESGF DILANPPGPD EEDDGYMDAF
1510 1520 1530 1540 1550
EFEFSDSPLL PCYNIQVSLS QGPRNWMLLS EVTKRLKMSS QTFTAENPHL
1560 1570 1580 1590 1600
EIVTITEAEF YKQVSLSQLF SSPEGLEGFS PDSREMVDLV EFTNELQTLL
1610
GSSIEWIDPE NETTYSSC
Length:1,618
Mass (Da):179,443
Last modified:July 27, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i70C8EA1080D1FACD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6URR9F6URR9_XENTR
BCL6 corepressor
bcor
1,697Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAMC01015882 Genomic DNA No translation available.
AAMC01015883 Genomic DNA No translation available.
AAMC01015884 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000033901; ENSXETP00000033901; ENSXETG00000015528

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01015882 Genomic DNA No translation available.
AAMC01015883 Genomic DNA No translation available.
AAMC01015884 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000033901; ENSXETP00000033901; ENSXETG00000015528

Organism-specific databases

XenbaseiXB-GENE-1010841 bcor

Phylogenomic databases

eggNOGiENOG410IHDH Eukaryota
ENOG410YT00 LUCA
GeneTreeiENSGT00940000153737

Gene expression databases

BgeeiENSXETG00000015528 Expressed in 13 organ(s), highest expression level in blastula
ExpressionAtlasiF6URS9 baseline

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
3.10.260.40, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR031628 BCOR
IPR032365 PUFD
IPR038227 PUFD_som_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF15808 BCOR, 1 hit
PF16553 PUFD, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6URS9_XENTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6URS9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 5, 2019
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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