Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 63 (02 Dec 2020)
Sequence version 2 (10 Apr 2019)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Myosin heavy chain 8

Gene

MYH8

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationARBA annotation, Motor protein, MyosinPROSITE-ProRule annotationARBA annotation
LigandATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myosin heavy chain 8Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYH8Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:56451, MYH8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6UP52

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000019706, Expressed in gluteus medius and 7 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6UP52, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 84Myosin N-terminal SH3-likeInterPro annotationAdd BLAST50
Domaini88 – 781Myosin motorInterPro annotationAdd BLAST694

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1124 – 1173DisorderedSequence analysisAdd BLAST50

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1196 – 1293Sequence analysisAdd BLAST98
Coiled coili1301 – 1335Sequence analysisAdd BLAST35
Coiled coili1343 – 1377Sequence analysisAdd BLAST35
Coiled coili1379 – 1441Sequence analysisAdd BLAST63
Coiled coili1456 – 1592Sequence analysisAdd BLAST137
Coiled coili1611 – 1645Sequence analysisAdd BLAST35
Coiled coili1660 – 1715Sequence analysisAdd BLAST56
Coiled coili1723 – 1806Sequence analysisAdd BLAST84
Coiled coili1808 – 1842Sequence analysisAdd BLAST35
Coiled coili1864 – 1926Sequence analysisAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1124 – 1154PolyampholyteSequence analysisAdd BLAST31

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161785

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000192_8_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6UP52

TreeFam database of animal gene trees

More...
TreeFami
TF314375

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.360, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR001609, Myosin_head_motor_dom
IPR027401, Myosin_IQ_contain_sf
IPR004009, Myosin_N
IPR008989, Myosin_S1_N
IPR002928, Myosin_tail
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00063, Myosin_head, 1 hit
PF02736, Myosin_N, 1 hit
PF01576, Myosin_tail_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00193, MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00242, MYSc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS51844, SH3_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6UP52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSASSDAEMA VFGEAAPYLR KSEKERIEAQ NKPFDAKTSV FVTEPKESYV
60 70 80 90 100
KSTIQSKEGG RITVKTEGGA TLTVREDQVF PMNPPKYDKI EDMAMMTHLH
110 120 130 140 150
EPGVLYNLKE RYAAWMIYTY SGLFCVTVNP YKWLPVYNPE VVAAYRGKKR
160 170 180 190 200
QEAPPHIFSI SDNAYQFMLT DRENQSILIT GESGAGKTVN TKRVIQYFAT
210 220 230 240 250
IAVTGEKKKE EPGKMQGTLE DQIISANPLL EAFGNAKTVR NDNSSRFGKF
260 270 280 290 300
IRIHFGTTGK LASADIETYL LEKSRVTFQL KAERSYHIFY QITSNKKPDL
310 320 330 340 350
IEMLLITTNP YDYAFISQGE ITVPSIDDQE ELMATDSAID ILGFTPEEKV
360 370 380 390 400
SIYKLTGAVM HYGNMKFKQK QREEQAEPDG TEVADKAAYL QSLNSADLLK
410 420 430 440 450
ALCYPRVKVG NEYVTKGQTV QQVYNAVGAL AKAVYEKMFL WMVTRINQQL
460 470 480 490 500
DTKQPRQYFI GVLDIAGFEI FDFNSLEQLC INFTNEKLQQ FFNHHMFVLE
510 520 530 540 550
QEEYKKEGIE WTFIDFGMDL AACIELIEKP LGIFSILEEE CMFPKATDTS
560 570 580 590 600
FKNKLYDQHL GKSANFQKPK VVKGKAEAHF SLIHYAGTVD YNITGWLDKN
610 620 630 640 650
KDPLNDTVVG LYQKSAMKTL ASLFSTYASA EADSSAKKGA KKKGSSFQTV
660 670 680 690 700
SALFRENLNK LMTNLRSTHP HFVRCIIPNE TKTPGAMEHE LVLHQLRCNG
710 720 730 740 750
VLEGIRICRK GFPSRILYGD FKQRYKLLNA SAIPEGQFID SKKASEKLLA
760 770 780 790 800
SIDIDHTQYK FGHTKVFFKA GLLGLLEEMR DEKLAQIITR TQAVCRGFLM
810 820 830 840 850
RVEYQKMLQR REALFCIQYN VRAFMNVKHW PWMKLFFKIK PLLKSAETEK
860 870 880 890 900
EMATMKEEFQ KTKDELAKSE AKRKELEEKM VTLLKEKNDL QLQVQSEADA
910 920 930 940 950
LADAEERCEQ LIKNKIQLEA KIKEATERAE DEEEINAELT AKKRKLEDEC
960 970 980 990 1000
SELKKDIDDL ELTLAKVEKE KHATENKVKN LTEEMAGLDE TIAKLTKEKK
1010 1020 1030 1040 1050
ALQEAHQQTL DDLQTEEDKV STLTKAKTKL EQQVDDLEGS LEQEKKLRMD
1060 1070 1080 1090 1100
LERAKRKLEG DLKLAQESTM DIENDKQQLD EKLKKKEFEI SNLLSKIEDE
1110 1120 1130 1140 1150
QAVEIQLQKK IKELQARIEE LEEEIEAERA SRAKAEKQRS DLSRELEEIS
1160 1170 1180 1190 1200
ERLEEAGGAT SAQIEMNKKR ETEFQKMRRD LEEATLQHEA TAAALRKKHA
1210 1220 1230 1240 1250
DSVAELGEQI DNLQRVKQKL EKEKSEMKME IDDLSSNAEA ISKAKANLEK
1260 1270 1280 1290 1300
MCRTLEDQLS ELKTKEEEQQ RLINDLTAQR ARLQTEAGEY SRQLDEKDAL
1310 1320 1330 1340 1350
VSQLSRSKQA FTQQIEELKR QLEEETKAKN ALAHALQSSR HDCDLLREQY
1360 1370 1380 1390 1400
EEEQEGKAEL QRALSKANSE VAQWRTKYET DAIQRTEELE EAKKKLAQRL
1410 1420 1430 1440 1450
QEAEEHVEAV NAKCASLEKT KQRLQNEVED LMLDVERSNA ACAALDKKQR
1460 1470 1480 1490 1500
NFDKVLSEWK QKYEETQAEL EASQKESRSL STELFKVKNA YEESLDQLET
1510 1520 1530 1540 1550
LKRENKNLQQ EISDLTEQIA EGGKQIHELE KIKKQVEQEK CDIQAALEEA
1560 1570 1580 1590 1600
EASLEHEEGK ILRIQLELNQ VKSEVDRKIA EKDEEIDQLK RNHIRVVETM
1610 1620 1630 1640 1650
QSTLDAEIRS RNDALRVKKK MEGDLNEMEI QLNHANRLAA ETLRNYRNTQ
1660 1670 1680 1690 1700
GILKDTQLHL DDALRGQEDL KEQLAMVERR ANLLQAEIEE LRATLEQTER
1710 1720 1730 1740 1750
SRKIAEQELL DASERVQLLH TQNTSLINTK KKLENDVSQL QSEVEEVIQE
1760 1770 1780 1790 1800
SRNAEEKAKK AITDAAMMAE ELKKEQDTSA HLERMKKNME QTVKDLQHRL
1810 1820 1830 1840 1850
DEAEQLALKG GKKQIQKLEA RVRELEGEVE SEQKRNAEAV KGLRKHERRV
1860 1870 1880 1890 1900
KELTYQTEED RKNVLRLQDL VDKLQAKVKS YKRQAEEAEE QSNANLAKFR
1910 1920 1930
KLQHELEEAE ERADIAESQV NKLRVKSREV HTKLSAE
Length:1,937
Mass (Da):222,889
Last modified:April 10, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD1BB831F3B72B9B7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2HYK9A0A3Q2HYK9_HORSE
Myosin heavy chain 8
MYH8
1,928Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_001504901.1, XM_001504851.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000024411; ENSECAP00000020277; ENSECAG00000019706

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100062893

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecb:100062893

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_001504901.1, XM_001504851.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PaxDbiF6UP52

Genome annotation databases

EnsembliENSECAT00000024411; ENSECAP00000020277; ENSECAG00000019706
GeneIDi100062893
KEGGiecb:100062893

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4626
VGNCiVGNC:56451, MYH8

Phylogenomic databases

GeneTreeiENSGT00940000161785
HOGENOMiCLU_000192_8_0_1
InParanoidiF6UP52
TreeFamiTF314375

Gene expression databases

BgeeiENSECAG00000019706, Expressed in gluteus medius and 7 other tissues
ExpressionAtlasiF6UP52, baseline

Family and domain databases

Gene3Di2.30.30.360, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR001609, Myosin_head_motor_dom
IPR027401, Myosin_IQ_contain_sf
IPR004009, Myosin_N
IPR008989, Myosin_S1_N
IPR002928, Myosin_tail
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00063, Myosin_head, 1 hit
PF02736, Myosin_N, 1 hit
PF01576, Myosin_tail_1, 1 hit
PRINTSiPR00193, MYOSINHEAVY
SMARTiView protein in SMART
SM00242, MYSc, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS51844, SH3_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6UP52_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6UP52
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: April 10, 2019
Last modified: December 2, 2020
This is version 63 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again