UniProtKB - F6UNH2 (F6UNH2_HORSE)
Protein
Reticulon
Gene
RTN2
Organism
Equus caballus (Horse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: ReticulonUniRule annotation |
Gene namesi | Name:RTN2Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:49261, RTN2 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 294 – 319 | HelicalUniRule annotationAdd BLAST | 26 | |
Transmembranei | 393 – 425 | HelicalUniRule annotationAdd BLAST | 33 |
Keywords - Cellular componenti
Endoplasmic reticulumUniRule annotationARBA annotation, MembraneExpressioni
Gene expression databases
Bgeei | ENSECAG00000022897, Expressed in triceps brachii and 20 other tissues |
ExpressionAtlasi | F6UNH2, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 275 – 475 | ReticulonInterPro annotationAdd BLAST | 201 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 11 – 66 | DisorderedSequence analysisAdd BLAST | 56 | |
Regioni | 80 – 264 | DisorderedSequence analysisAdd BLAST | 185 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 18 – 32 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 33 – 50 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 173 – 187 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 199 – 227 | PolarSequence analysisAdd BLAST | 29 | |
Compositional biasi | 234 – 249 | PolyampholyteSequence analysisAdd BLAST | 16 |
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000160599 |
InParanoidi | F6UNH2 |
TreeFami | TF105431 |
Family and domain databases
InterProi | View protein in InterPro IPR003388, Reticulon |
Pfami | View protein in Pfam PF02453, Reticulon, 1 hit |
PROSITEi | View protein in PROSITE PS50845, RETICULON, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6UNH2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
FGQSKLLRVF DSFPLAEEAP STASSTPDST EGGNDDSDFR ELHTAREFSE
60 70 80 90 100
DDEEETTSQD WGTPRELTFS YIAFDGVVGS GARRDSAARR PRPQGRSVSE
110 120 130 140 150
PREPPPQPGL GDSLESIPSL SQSPEPGRRG DPDAAPPAER PLEDLGLQLD
160 170 180 190 200
QLAWAARGAG SGEDSATSSS TPLEDEEPDR SEAGEAGKEL DLQLGVAQSS
210 220 230 240 250
PHEVLTPQPS PGSGTPQART PSPPGSRDSN CWPDEPSLDQ KEEEPGGQLE
260 270 280 290 300
REPITGQSLD STDQSEFTLE PHLLVADLLY WKDTRTSGVV FTGLMVSLLC
310 320 330 340 350
LLHFSIVSVV AHVALLLLCG TISLRVYRKV LQAIHRGDGT NPFQAYLDVD
360 370 380 390 400
LTLTQEQKEH LSQQIASRVV SAATQLRHFF LVEDLVDSFK LALLFYILTF
410 420 430 440 450
VGAVFNGLTL LILGVICLFT IPLLYRQHQA QIDQYVGLVT NQLSHIKAKI
460 470
RAKIPGTGAL ASAAAAVSGS KAKAE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF6UMT3 | F6UMT3_HORSE | Reticulon | RTN2 | 542 | Annotation score: |
Sequence databases
RefSeqi | XP_005596405.1, XM_005596348.2 |
Genome annotation databases
Ensembli | ENSECAT00000024603; ENSECAP00000020446; ENSECAG00000022897 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_005596405.1, XM_005596348.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6UNH2 |
Genome annotation databases
Ensembli | ENSECAT00000024603; ENSECAP00000020446; ENSECAG00000022897 |
Organism-specific databases
VGNCi | VGNC:49261, RTN2 |
Phylogenomic databases
GeneTreei | ENSGT00940000160599 |
InParanoidi | F6UNH2 |
TreeFami | TF105431 |
Gene expression databases
Bgeei | ENSECAG00000022897, Expressed in triceps brachii and 20 other tissues |
ExpressionAtlasi | F6UNH2, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR003388, Reticulon |
Pfami | View protein in Pfam PF02453, Reticulon, 1 hit |
PROSITEi | View protein in PROSITE PS50845, RETICULON, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6UNH2_HORSE | |
Accessioni | F6UNH2Primary (citable) accession number: F6UNH2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | October 7, 2020 | |
This is version 50 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |