UniProtKB - F6UMT3 (F6UMT3_HORSE)
Protein
Reticulon
Gene
RTN2
Organism
Equus caballus (Horse)
Status
Functioni
GO - Biological processi
- intracellular protein transmembrane transport Source: Ensembl
- regulation of glucose import Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: ReticulonUniRule annotation |
Gene namesi | Name:RTN2Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:49261, RTN2 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
- terminal cisterna Source: Ensembl
Plasma Membrane
- T-tubule Source: Ensembl
Other locations
- integral component of membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 361 – 386 | HelicalUniRule annotationAdd BLAST | 26 | |
Transmembranei | 460 – 492 | HelicalUniRule annotationAdd BLAST | 33 |
Keywords - Cellular componenti
Endoplasmic reticulumUniRule annotationARBA annotation, MembraneExpressioni
Gene expression databases
Bgeei | ENSECAG00000022897, Expressed in triceps brachii and 20 other tissues |
ExpressionAtlasi | F6UMT3, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 342 – 542 | ReticulonInterPro annotationAdd BLAST | 201 |
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000160599 |
HOGENOMi | CLU_508939_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR003388, Reticulon |
Pfami | View protein in Pfam PF02453, Reticulon, 1 hit |
PROSITEi | View protein in PROSITE PS50845, RETICULON, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6UMT3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGQVLPVFAH CKEAPSTASS TPDSTEGGND DSDFRELHTA REFSEDDEEE
60 70 80 90 100
TTSQDWGTPR ELTFSYIAFD GVVGSGARRD SAARRPRPQG RSVSEPREPP
110 120 130 140 150
PQPGLGDSLE SIPSLSQSPE PGRRGDPDAA PPAERPLEDL GLQLDQLAWA
160 170 180 190 200
ARGAGSGEDS ATSSSTPLED EEPDRSEAGE AGKELDLQLG VAQSSPHEVL
210 220 230 240 250
TPQPSPGSGT PQARTPSPPG SRDSNCWPDE PSLDQKEEEP GGQLEREPIT
260 270 280 290 300
GQSLDSTDQS EFTLEPHLLG TARAWLQTSR LWAVCKESRP FLELSPPLWR
310 320 330 340 350
AIGWVGGPAP APALRVPPKW AKSPRSSSVR SLSLGAEMGS KVADLLYWKD
360 370 380 390 400
TRTSGVVFTG LMVSLLCLLH FSIVSVVAHV ALLLLCGTIS LRVYRKVLQA
410 420 430 440 450
IHRGDGTNPF QAYLDVDLTL TQEQKEHLSQ QIASRVVSAA TQLRHFFLVE
460 470 480 490 500
DLVDSFKLAL LFYILTFVGA VFNGLTLLIL GVICLFTIPL LYRQHQAQID
510 520 530 540
QYVGLVTNQL SHIKAKIRAK IPGTGALASA AAAVSGSKAK AE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF6UNH2 | F6UNH2_HORSE | Reticulon | RTN2 | 475 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000024614; ENSECAP00000020454; ENSECAG00000022897 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSECAT00000024614; ENSECAP00000020454; ENSECAG00000022897 |
Organism-specific databases
VGNCi | VGNC:49261, RTN2 |
Phylogenomic databases
GeneTreei | ENSGT00940000160599 |
HOGENOMi | CLU_508939_0_0_1 |
Gene expression databases
Bgeei | ENSECAG00000022897, Expressed in triceps brachii and 20 other tissues |
ExpressionAtlasi | F6UMT3, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR003388, Reticulon |
Pfami | View protein in Pfam PF02453, Reticulon, 1 hit |
PROSITEi | View protein in PROSITE PS50845, RETICULON, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6UMT3_HORSE | |
Accessioni | F6UMT3Primary (citable) accession number: F6UMT3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | October 7, 2020 | |
This is version 45 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |