UniProtKB - F6UM04 (F6UM04_ORNAN)
Protein
Submitted name:
Myogenin
Gene
MYOG
Organism
Ornithorhynchus anatinus (Duckbill platypus)
Status
Functioni
GO - Molecular functioni
- chromatin DNA binding Source: Ensembl
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
- E-box binding Source: Ensembl
- protein dimerization activity Source: InterPro
GO - Biological processi
- cellular response to estradiol stimulus Source: Ensembl
- cellular response to growth factor stimulus Source: Ensembl
- cellular response to lithium ion Source: Ensembl
- cellular response to tumor necrosis factor Source: Ensembl
- negative regulation of cell population proliferation Source: Ensembl
- ossification Source: Ensembl
- positive regulation of cell cycle arrest Source: Ensembl
- positive regulation of muscle atrophy Source: Ensembl
- positive regulation of myoblast differentiation Source: Ensembl
- positive regulation of skeletal muscle fiber development Source: Ensembl
- regulation of myoblast fusion Source: Ensembl
- regulation of skeletal muscle satellite cell proliferation Source: Ensembl
- response to denervation involved in regulation of muscle adaptation Source: Ensembl
- skeletal muscle fiber development Source: Ensembl
- striated muscle atrophy Source: Ensembl
Keywordsi
Molecular function | Developmental proteinARBA annotation, DNA-bindingARBA annotation |
Biological process | DifferentiationARBA annotation, MyogenesisARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: MyogeninImported |
Gene namesi | Name:MYOGImported |
Organismi | Ornithorhynchus anatinus (Duckbill platypus)Imported |
Taxonomic identifieri | 9258 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Monotremata › Ornithorhynchidae › Ornithorhynchus |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleoplasm Source: Ensembl
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSOANG00000002107, Expressed in heart and 2 other tissues |
Family & Domainsi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00950000182959 |
HOGENOMi | CLU_100258_0_0_1 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR002546, MyoD_N IPR039704, Myogenic_factor |
PANTHERi | PTHR11534, PTHR11534, 1 hit |
Pfami | View protein in Pfam PF01586, Basic, 1 hit PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00520, BASIC, 1 hit SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
F6UM04-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEFYETSPYF FPEQRLYEDE NYLPGRLQGY EQPGYGEPAE LGLCPEGRGA
60 70 80 90 100
LEEPGPGGPD HCPGQCLPWT CKVCKRKTVS VDRRRAATLR EKRRLKKVNE
110 120 130 140 150
AFEALKRSTL LNPNQRLPKV EILRSAIQYI ERLQALLSSL NQEERDLRFR
160 170 180 190 200
SGAPQPGVPS ECGSHSASCS PEWSTALEFS GNPGDPLLHD DSADARNLHS
210 220
LTSIVESITV EDVSAAFPGE TRTN
Genome annotation databases
Ensembli | ENSOANT00000003345; ENSOANP00000003344; ENSOANG00000002107 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSOANT00000003345; ENSOANP00000003344; ENSOANG00000002107 |
Phylogenomic databases
GeneTreei | ENSGT00950000182959 |
HOGENOMi | CLU_100258_0_0_1 |
Gene expression databases
Bgeei | ENSOANG00000002107, Expressed in heart and 2 other tissues |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR002546, MyoD_N IPR039704, Myogenic_factor |
PANTHERi | PTHR11534, PTHR11534, 1 hit |
Pfami | View protein in Pfam PF01586, Basic, 1 hit PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00520, BASIC, 1 hit SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6UM04_ORNAN | |
Accessioni | F6UM04Primary (citable) accession number: F6UM04 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 2, 2020 | |
Last modified: | December 2, 2020 | |
This is version 46 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |