UniProtKB - F6UG31 (F6UG31_HORSE)
Protein
Matrix remodeling-associated protein 8
Gene
MXRA8
Organism
Equus caballus (Horse)
Status
Functioni
GO - Biological processi
- cell adhesion Source: InterPro
- establishment of glial blood-brain barrier Source: Ensembl
Names & Taxonomyi
Protein namesi | Recommended name: Matrix remodeling-associated protein 8ARBA annotation |
Gene namesi | Name:MXRA8Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:58639, MXRA8 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- cell surface Source: Ensembl
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 343 – 363 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membraneARBA annotation, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5018591404 | 24 – 444 | Matrix remodeling-associated protein 8Sequence analysisAdd BLAST | 421 |
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationProteomic databases
PaxDbi | F6UG31 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000020731, Expressed in articular cartilage of joint and 19 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 158 | Ig-likeInterPro annotationAdd BLAST | 130 | |
Domaini | 161 – 293 | Ig-likeInterPro annotationAdd BLAST | 133 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 295 – 321 | DisorderedSequence analysisAdd BLAST | 27 |
Keywords - Domaini
Immunoglobulin domainARBA annotation, SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000001509 |
HOGENOMi | CLU_1464499_0_0_1 |
InParanoidi | F6UG31 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set IPR042472, MXRA8 |
PANTHERi | PTHR44793, PTHR44793, 1 hit |
Pfami | View protein in Pfam PF07686, V-set, 2 hits |
SMARTi | View protein in SMART SM00409, IG, 2 hits SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6UG31-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MELRSRVLFW KLVLLQSSAV LLSSGPSGPG MAGSSVVSES VVSWAAGAQA
60 70 80 90 100
TLRCQSPRMV WTQDRLHDRQ RVVHWDLSGG PAGGPTRRLV DMYSAGEQRV
110 120 130 140 150
YETRDRGRLL LPPSAFHDGN FSLLIRAVEE TDEGLYTCNL HHHYCHLYES
160 170 180 190 200
LAVRLEVTDN PRAAGAHWDG EKEVLVAERG APALLTCVNR AHVWTDRHLE
210 220 230 240 250
EAQQVVHWDR QPPGVPHDRA DRLLDLYASG ERRAYGPPFL RDRVAVAVDA
260 270 280 290 300
FARGDFSLRI DPLEPADEGT YSCHLHHHYC GLHERRVFHL RVTEPAAQPP
310 320 330 340 350
PRDSPGNGSS HSSAPRPDPT LARGRSVINV IVPEGRAHFF QQLGYVLATL
360 370 380 390 400
LLFILLLITV ILATRQRRRG GYEYSGKKSG RSKGKDMNME EFAVATGDQP
410 420 430 440
LYRTEDIQLD YKNNILKERA GLAHSPLPAK YVDLDNEFRK EYCK
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PZW7 | A0A5F5PZW7_HORSE | Matrix remodeling-associated protei... | MXRA8 | 342 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000021994; ENSECAP00000018156; ENSECAG00000020731 |
Similar proteinsi
Cross-referencesi
3D structure databases
SMRi | F6UG31 |
ModBasei | Search... |
Proteomic databases
PaxDbi | F6UG31 |
Genome annotation databases
Ensembli | ENSECAT00000021994; ENSECAP00000018156; ENSECAG00000020731 |
Organism-specific databases
VGNCi | VGNC:58639, MXRA8 |
Phylogenomic databases
GeneTreei | ENSGT00390000001509 |
HOGENOMi | CLU_1464499_0_0_1 |
InParanoidi | F6UG31 |
Gene expression databases
Bgeei | ENSECAG00000020731, Expressed in articular cartilage of joint and 19 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set IPR042472, MXRA8 |
PANTHERi | PTHR44793, PTHR44793, 1 hit |
Pfami | View protein in Pfam PF07686, V-set, 2 hits |
SMARTi | View protein in SMART SM00409, IG, 2 hits SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6UG31_HORSE | |
Accessioni | F6UG31Primary (citable) accession number: F6UG31 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | April 7, 2021 | |
This is version 44 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |