UniProtKB - F6UDC6 (F6UDC6_HUMAN)

BLAST

>tr|F6UDC6|F6UDC6_HUMAN Double-stranded RNA-binding protein Staufen homolog 1 (Fragment) OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=1
MCEVSRGWKPCTEGILKVRPTRKISYEESITPTVELNALCMKLGKKPMYKPVDPYSRMQS
TYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQ
NEPLPERLE

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History
Entry version 38 (12 Sep 2018)
Sequence version 1 (03 Apr 2013)
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Protein

Submitted name:

Double-stranded RNA-binding protein Staufen homolog 1

Gene

STAU1

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

RNA binding Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	RNA-bindingPROSITE-ProRule annotation

Molecular function

RNA-bindingPROSITE-ProRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Double-stranded RNA-binding protein Staufen homolog 1Imported
Gene namesⁱ	Name:STAU1Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 20

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000124214.19
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11370 STAU1

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000124214

OpenTargetsⁱ

ENSG00000124214

PTM / Processingⁱ

Proteomic databases

EPDⁱ	F6UDC6
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	F6UDC6
PeptideAtlas More...PeptideAtlasⁱ	F6UDC6
PRIDEⁱ	F6UDC6

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000124214 Expressed in 240 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasⁱ	F6UDC6 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	F6UDC6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	31 – 121	DRBMInterPro annotationAdd BLAST		91

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140998

GeneTreeⁱ

ENSGT00900000140998

Family and domain databases

InterProⁱ	View protein in InterPro IPR014720 dsRBD_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00035 dsrm, 1 hit
SMARTⁱ	View protein in SMART SM00358 DSRM, 1 hit
PROSITEⁱ	View protein in PROSITE PS50137 DS_RBD, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show all Align All

F6UDC6-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MCEVSRGWKP CTEGILKVRP TRKISYEESI TPTVELNALC MKLGKKPMYK 
        60         70         80         90        100
PVDPYSRMQS TYNYNMRGGA YPPRYFYPFP VPPLLYQVEL SVGGQQFNGK 
       110        120 
GKTRQAAKHD AAAKALRILQ NEPLPERLE

Length:129

Mass (Da):14,726

Last modified:April 3, 2013 - v1

Checksum:ⁱBC3BF6ABB37F824C

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

O95793	STAU1_HUMAN	Double-stranded RNA-binding protein... Double-stranded RNA-binding protein Staufen homolog 1	STAU1 STAU	577	Annotation score:
Q5JW30	Q5JW30_HUMAN	Double-stranded RNA-binding protein... Double-stranded RNA-binding protein Staufen homolog 1	STAU1	494	Annotation score:
A0A087X1A5	A0A087X1A5_HUMAN	Double-stranded RNA-binding protein... Double-stranded RNA-binding protein Staufen homolog 1	STAU1	493	Annotation score:
Q5JW28	Q5JW28_HUMAN	Double-stranded RNA-binding protein... Double-stranded RNA-binding protein Staufen homolog 1	STAU1	199	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	129	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL133174 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL133174 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000456866; ENSP00000398785; ENSG00000124214
UCSC genome browser More...UCSCⁱ	uc061xpq.1 human

Protein	Similar proteins		Species	Score	Length	Source
F6UDC6	Uncharacterized protein		CALJA		663	UniRef90_F7INW0
Staufen double-stranded RNA binding protein 1		SAIBB		540
STAU1 protein (Fragment)		BOVIN		531
Uncharacterized protein		MACMU		128
UPI000B504CEA		AOTNA		496
+5

Protein	Similar proteins		Species	Score	Length	Source
F6UDC6	Staufen double-stranded RNA binding protein 1		BOVIN		699	UniRef50_F1MH34
Double-stranded RNA-binding protein Staufen homolog 1 (Fragment)		AILME		700
Double-stranded RNA-binding protein Staufen like protein 1		MYOBR		696
double-stranded RNA-binding protein Staufen homolog 1 isoform X5		DELLE		687
double-stranded RNA-binding protein Staufen homolog 1 isoform X4		PHYCD		687
+782

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL133174 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL133174 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	F6UDC6
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	F6UDC6
MaxQBⁱ	F6UDC6
PeptideAtlasⁱ	F6UDC6
PRIDEⁱ	F6UDC6

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000456866; ENSP00000398785; ENSG00000124214
UCSCⁱ	uc061xpq.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000124214.19
HGNCⁱ	HGNC:11370 STAU1
OpenTargetsⁱ	ENSG00000124214
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

GeneTreeⁱ	ENSGT00900000140998

GeneTreeⁱ

ENSGT00900000140998

Miscellaneous databases

ChiTaRSⁱ	STAU1 human

ChiTaRSⁱ

STAU1 human

Gene expression databases

Bgeeⁱ	ENSG00000124214 Expressed in 240 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasⁱ	F6UDC6 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR014720 dsRBD_dom
Pfamⁱ	View protein in Pfam PF00035 dsrm, 1 hit
SMARTⁱ	View protein in SMART SM00358 DSRM, 1 hit
PROSITEⁱ	View protein in PROSITE PS50137 DS_RBD, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F6UDC6_HUMAN
Accessionⁱ	F6UDC6Primary (citable) accession number: F6UDC6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 3, 2013
	Last sequence update:	April 3, 2013
	Last modified:	September 12, 2018
	This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F6UDC6 (F6UDC6_HUMAN)

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Double-stranded RNA-binding protein Staufen homolog 1

STAU1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ