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Entry version 60 (07 Apr 2021)
Sequence version 2 (11 Dec 2019)
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Protein

E3 ubiquitin-protein ligase

Gene

UBR2

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.UniRule annotationARBA annotation EC:2.3.2.27

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.UniRule annotationARBA annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri125 – 196UBR-typePROSITE-ProRule annotationAdd BLAST72

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseUniRule annotationARBA annotation
Biological processUbl conjugation pathwayUniRule annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligaseUniRule annotation (EC:2.3.2.27UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UBR2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:24748, UBR2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000020598, Expressed in gluteus medius and 22 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6U418, baseline

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F6U418

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini125 – 196UBR-typeInterPro annotationAdd BLAST72

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1033 – 1061DisorderedSequence analysisAdd BLAST29
Regioni1288 – 1322DisorderedSequence analysisAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili878 – 898Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1047 – 1061PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1288 – 1308PolarSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UBR1 family.UniRule annotationARBA annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri125 – 196UBR-typePROSITE-ProRule annotationAdd BLAST72

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerUniRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183075

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001801_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6U418

Identification of Orthologs from Complete Genome Data

More...
OMAi
PEWECAF

Database of Orthologous Groups

More...
OrthoDBi
81415at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1390.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003769, ClpS_core
IPR044046, E3_ligase_UBR-like_C
IPR014719, Ribosomal_L7/12_C/ClpS-like
IPR039164, UBR1-like
IPR036390, WH_DNA-bd_sf
IPR003126, Znf_UBR

The PANTHER Classification System

More...
PANTHERi
PTHR21497, PTHR21497, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02617, ClpS, 1 hit
PF18995, PRT6_C, 1 hit
PF02207, zf-UBR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00396, ZnF_UBR1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 1 hit
SSF54736, SSF54736, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51157, ZF_UBR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F6U418-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASELELEMQ AIDRSLLECS AEEIAGRLQA CIYFISAFIN AIWSIFLQYQ
60 70 80 90 100
CYVTKWLQAT DLTREVYQHL AHYVPKIYCR SPNPCPQKED MVAQHVLLAP
110 120 130 140 150
MEWYLCGEDS EFGFPKLQQA NKPSHLCGRV FKVGEPTYSC RDCAVDPTCV
160 170 180 190 200
LCMDCFLGSI HRDHRYRMTT SGGGGFCDCG DTEAWKEGPY CQKHELNTPE
210 220 230 240 250
IEEEEDPLVH LSEDVIARSY NIFTIMFQYA VEILTWEKES ELPADLEMVE
260 270 280 290 300
KSDTYYCMLF NDEVHTYEQV IYTLQKAVNC TQKEAIGFAT TVDRDGRRSV
310 320 330 340 350
RCGDFQYCEQ AKSIIVRNTS SRQTKPLKVQ VMHSSLVAHQ SFGLKVLSWL
360 370 380 390 400
GSVIGYSDGL RRILCQVGLQ EGPDGENSSL VDRLMLSDSK LWKGARSVYH
410 420 430 440 450
QLFMSSLLMD LKYKKLFAVR FAKNYERLQS DYVTDDHDRE FSIADLSVQI
460 470 480 490 500
FTVPSLARML ITEENLMTII IKTFMDHLRH RDTQGRFQFE RYTALQAFKF
510 520 530 540 550
RRVQSLILDL KYVLISKPTE WSDDLREKFL EGFDAFLELL KCMQGMDPIT
560 570 580 590 600
RQVGQHIEME PEWEAAFTLQ MKLTHVISMM QDWCALDEKV LIEAYKKCLT
610 620 630 640 650
VLMQCHGGFT DGEQPITLSI CGHSVETIRY CVSQEKVSIH LPVSRLLAGL
660 670 680 690 700
HVLLSKSEVA YKFPELLPLS ELSPPMLIEH PLRCLVLCAQ VHAGMWRRNG
710 720 730 740 750
FSLVNQIYYY HNVKCRREMF DKDIVMLQTG VSMMDPNHFL MIMLSRFELY
760 770 780 790 800
QIFSTPDYGK RFSSEITHKD VVQQNNTLIE EMLYLIIMLV GERFSPGVGQ
810 820 830 840 850
VNATDDIKRE IIHQLSIKPM AHSELVKSLP EDENKETGME SVIEAVAHFK
860 870 880 890 900
KPGLTGRGMY ELKPECAKEF NLYFYHFSRA EQSKAEEAQR KLKRQNREDT
910 920 930 940 950
ALPPPVLPPF CPLFASLVNI LQSDVMLCIM RTILQWAVEH NGYAWSESML
960 970 980 990 1000
QRVLHLIGMA LQEEKQHLEN VTEEHVVTFT FTQKISKPGE APNNSPSILA
1010 1020 1030 1040 1050
MLETLQNAPY LEVHKDMIRW ILKTFNAIKK LRESSSPSPV AETEGTIMEE
1060 1070 1080 1090 1100
SSRDKDKAER KRKAEIARLR REKIMAQMSE MQRHFIDENK ELFQQTLELD
1110 1120 1130 1140 1150
ASASAVLDNS PVVSDKTLTA LGPAQTQVPE QRQFVTCILC QEEQEVKVES
1160 1170 1180 1190 1200
KAMVLAAFVQ RSTVLSKDRS KFIQDPEKYD PLFMHPDLSC GTHTGSCGHI
1210 1220 1230 1240 1250
MHAHCWQRYF DSVQAKEQRR QQRLRLHTSY DVENGEFLCP LCECLSNTVI
1260 1270 1280 1290 1300
PLLLPPRKIF NSRLNFSDQP NLTQWIRTIS QQIKALQALG KEESTPHTTS
1310 1320 1330 1340 1350
SKNSENMDEF QLPEGFRPDF RPKNPYSESI KEMLKTFGTA TYKVGLKLHP
1360 1370 1380 1390 1400
NEEDPRVPVM CWGSCAYTIQ SLERILSDED KPLFGPLPCR LDDCLRSLTR
1410 1420 1430 1440 1450
FAAAHWTVAS LSVVQGHFCK LFASLVPDDN HGDLPCILDI DMFHLLVGLV
1460 1470 1480 1490 1500
LAFPALQCQD FSGTSLGTGD LHIFRLVTMA HIIQLLLTSC TEENGMDEES
1510 1520 1530 1540 1550
PAGEEESAVL ALYKTLQQCT GSALKEVPPG WHLWRNVRAG ILPFLKCSAL
1560 1570 1580 1590 1600
FFHYLNGVPS PPEMQVSGAS HFEHLCNYLS LPSNLVSLFQ ENNEITKSLI
1610 1620 1630 1640 1650
ESWCHNIEVK RYLEGERDAI SYPRESNKLI DLPEDYSSLI NQASNFSCPK
1660 1670 1680 1690 1700
SGGDKSRAPT LCLVCGTLLC SQSYCCQTEL EGEDVGACTA HTYSCGSGVG
1710 1720 1730 1740 1750
IFLRVRECQV LFLAGKTKGC FYSPPYLDDY GETDQGLRRG NPLHLCQERF
1760 1770 1780
KKIQKLWQQH SVTEEIGHAQ EANQTLVGID WQHL
Length:1,784
Mass (Da):203,696
Last modified:December 11, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i99CD9F9E68B533C4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6U471F6U471_HORSE
E3 ubiquitin-protein ligase
UBR2
1,756Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HX42A0A3Q2HX42_HORSE
E3 ubiquitin-protein ligase
UBR2
1,762Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GXP5A0A3Q2GXP5_HORSE
E3 ubiquitin-protein ligase
UBR2
1,737Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I3N6A0A3Q2I3N6_HORSE
E3 ubiquitin-protein ligase
UBR2
1,713Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HKK1A0A3Q2HKK1_HORSE
E3 ubiquitin-protein ligase
UBR2
1,735Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I0W8A0A3Q2I0W8_HORSE
E3 ubiquitin-protein ligase
UBR2
1,718Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000022605; ENSECAP00000018689; ENSECAG00000020598

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiF6U418
ModBaseiSearch...

Genome annotation databases

EnsembliENSECAT00000022605; ENSECAP00000018689; ENSECAG00000020598

Organism-specific databases

VGNCiVGNC:24748, UBR2

Phylogenomic databases

GeneTreeiENSGT00950000183075
HOGENOMiCLU_001801_2_0_1
InParanoidiF6U418
OMAiPEWECAF
OrthoDBi81415at2759

Enzyme and pathway databases

UniPathwayiUPA00143

Gene expression databases

BgeeiENSECAG00000020598, Expressed in gluteus medius and 22 other tissues
ExpressionAtlasiF6U418, baseline

Family and domain databases

Gene3Di3.30.1390.10, 1 hit
InterProiView protein in InterPro
IPR003769, ClpS_core
IPR044046, E3_ligase_UBR-like_C
IPR014719, Ribosomal_L7/12_C/ClpS-like
IPR039164, UBR1-like
IPR036390, WH_DNA-bd_sf
IPR003126, Znf_UBR
PANTHERiPTHR21497, PTHR21497, 1 hit
PfamiView protein in Pfam
PF02617, ClpS, 1 hit
PF18995, PRT6_C, 1 hit
PF02207, zf-UBR, 1 hit
SMARTiView protein in SMART
SM00396, ZnF_UBR1, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
SSF54736, SSF54736, 1 hit
PROSITEiView protein in PROSITE
PS51157, ZF_UBR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6U418_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6U418
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: April 7, 2021
This is version 60 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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