UniProtKB - F6TIA2 (F6TIA2_HORSE)
Protein
Submitted name:
Adhesion G protein-coupled receptor G5
Gene
ADGRG5
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- G protein-coupled receptor activity Source: InterPro
GO - Biological processi
- cell surface receptor signaling pathway Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Adhesion G protein-coupled receptor G5Imported |
Gene namesi | Name:ADGRG5Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:15110, ADGRG5 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 246 – 267 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 288 – 307 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 313 – 340 | HelicalSequence analysisAdd BLAST | 28 | |
Transmembranei | 352 – 374 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 409 – 433 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 454 – 477 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 483 – 502 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | Sequence analysisAdd BLAST | 23 | |
ChainiPRO_5023806680 | 24 – 526 | Sequence analysisAdd BLAST | 503 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000021014, Expressed in blood and 18 other tissues |
ExpressionAtlasi | F6TIA2, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 184 – 236 | GPSInterPro annotationAdd BLAST | 53 | |
Domaini | 246 – 505 | G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST | 260 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000161359 |
HOGENOMi | CLU_002753_3_9_1 |
Family and domain databases
InterProi | View protein in InterPro IPR017981, GPCR_2-like IPR000832, GPCR_2_secretin-like IPR003910, GPR1/GPR3/GPR5 IPR000203, GPS |
Pfami | View protein in Pfam PF00002, 7tm_2, 1 hit PF01825, GPS, 1 hit |
PRINTSi | PR00249, GPCRSECRETIN PR01422, GPR56ORPHANR |
SMARTi | View protein in SMART SM00303, GPS, 1 hit |
PROSITEi | View protein in PROSITE PS50261, G_PROTEIN_RECEP_F2_4, 1 hit PS50221, GPS, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F6TIA2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERRGALFLG LCLVTAGSGT ADASGESLRW MQRMEAAARS RRPTSPPEFI
60 70 80 90 100
HGLEQRLLNA TFGGHNLTLQ TRTIQSLAFR LGCDFAGLSL SSSIMEWVPQ
110 120 130 140 150
PQAQTRHTMQ FPAELTQNAC RARPRELRLI CIYFLATYYF QSDTNASLLN
160 170 180 190 200
NYVLGAQLGH EHVNNLREPI NISFWHNQSL EGYMVTCVFW KEGASQHYWG
210 220 230 240 250
VWSPEGCRTE QPSPSQVLCR CNHLSYFAVL MQLSAAPVPV ELLAPLTYIS
260 270 280 290 300
LVGCSISVMA SLLTLLLHVH TRRQRDSITR IHMNLHASVL LLNVAFLLSP
310 320 330 340 350
TLAVTPVPGS VCAALAAVLH FALLSCLTWM AIEGFNLYLL LGRVYNIYIR
360 370 380 390 400
RYVLKLCAVG WGVPAFLVLL VLAVKSSAYG PRTILLSDSQ GNGTSFQNMS
410 420 430 440 450
MCWVRSPEVH SVLVMGYGGL TSLFNLVVLA WALRALRRLK AREKAPGPRA
460 470 480 490 500
CRDTVTVLGL TVLLGTTWAL AFFSFGVFLL PQLFLFTVFN SLYGFFLFLW
510 520
FCSRRCRSEA VAEAEMEAFS SAQTVS
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF6TIG6 | F6TIG6_HORSE | Adhesion G protein-coupled receptor... | ADGRG5 | 650 | Annotation score: | ||
A0A3Q2HMC9 | A0A3Q2HMC9_HORSE | Adhesion G protein-coupled receptor... | ADGRG5 | 613 | Annotation score: | ||
A0A3Q2I901 | A0A3Q2I901_HORSE | Adhesion G protein-coupled receptor... | ADGRG5 | 611 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000022370; ENSECAP00000018484; ENSECAG00000021014 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSECAT00000022370; ENSECAP00000018484; ENSECAG00000021014 |
Organism-specific databases
VGNCi | VGNC:15110, ADGRG5 |
Phylogenomic databases
GeneTreei | ENSGT00940000161359 |
HOGENOMi | CLU_002753_3_9_1 |
Gene expression databases
Bgeei | ENSECAG00000021014, Expressed in blood and 18 other tissues |
ExpressionAtlasi | F6TIA2, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR017981, GPCR_2-like IPR000832, GPCR_2_secretin-like IPR003910, GPR1/GPR3/GPR5 IPR000203, GPS |
Pfami | View protein in Pfam PF00002, 7tm_2, 1 hit PF01825, GPS, 1 hit |
PRINTSi | PR00249, GPCRSECRETIN PR01422, GPR56ORPHANR |
SMARTi | View protein in SMART SM00303, GPS, 1 hit |
PROSITEi | View protein in PROSITE PS50261, G_PROTEIN_RECEP_F2_4, 1 hit PS50221, GPS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6TIA2_HORSE | |
Accessioni | F6TIA2Primary (citable) accession number: F6TIA2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | August 12, 2020 | |
This is version 52 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |