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Protein
Submitted name:

Transglutaminase 2

Gene

TGM2

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei277UniRule annotation1
Active sitei335UniRule annotation1
Active sitei358UniRule annotation1
Metal bindingi398CalciumUniRule annotation1
Metal bindingi400CalciumUniRule annotation1
Metal bindingi447CalciumUniRule annotation1
Metal bindingi452CalciumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transglutaminase 2Imported
Gene namesi
Name:TGM2Imported
OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
Proteomesi
  • UP000002280 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMODG00000000203 Expressed in 7 organ(s), highest expression level in female gonad

Interactioni

Protein-protein interaction databases

STRINGi13616.ENSMODP00000000237

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini269 – 361TGcInterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG410IFMV Eukaryota
ENOG410XQEZ LUCA
GeneTreeiENSGT00760000119108
InParanoidiF6TFD4
KOiK05625
OrthoDBiEOG091G030K
TreeFamiTF324278

Family and domain databases

Gene3Di2.60.40.10, 3 hits
3.90.260.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR038765 Papain_like_cys_pep_sf
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N
PfamiView protein in Pfam
PF00927 Transglut_C, 2 hits
PF01841 Transglut_core, 1 hit
PF00868 Transglut_N, 1 hit
PIRSFiPIRSF000459 TGM_EBP42, 1 hit
SMARTiView protein in SMART
SM00460 TGc, 1 hit
SUPFAMiSSF49309 SSF49309, 2 hits
SSF54001 SSF54001, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00547 TRANSGLUTAMINASES, 1 hit

Sequencei

Sequence statusi: Complete.

F6TFD4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKALVIDKI NQDYEKNGKN HRTSALTQDR LVLRRGQSFS ISLTFHGRGF
60 70 80 90 100
EASTDKLFFL VETGPRPNET VFTKAKFPLS TTHSEGSWEA SMVSQEGHTL
110 120 130 140 150
NLAFSSPANA PIGYYKLSME SITGSQHHIS SITGFVLLFN PWCKEDSVYM
160 170 180 190 200
EEEEFRQEYV MNQHGLIFQG APACIEKIPW NFGQFEDGIL DICIELMDMN
210 220 230 240 250
PKFIRDCGRD CSRRNSPIYV SRVISAMVNC NDDKGILFGR WDNNYKDGIN
260 270 280 290 300
PMSWIGSVDI LKKWKKSGCC QVKYGQCWVF AAVACTVLRC LGIPSRVVTN
310 320 330 340 350
YNSAHDSNAN LVVDLYTDEK GMTVKHSNES IWNYHCWTES WMTRPDLKPE
360 370 380 390 400
CNGWQVIDPT PQEKSEGAFC CGPASVNAIK NGDVNTKYDA PFVFAEVNAD
410 420 430 440 450
VVKWIKKSNG TTEKAYTETT IVGMMISTKA VGKDEREDIT HLYKYPENSK
460 470 480 490 500
EERESFKRAN HMNKLGCRDD PSSDEKLKIK IKVSPDMNKG NDFDVFAMIK
510 520 530 540 550
NGFSEEQTCH LLIMARTMSY NGILGPECAK KEMHSVTLEP LSEKKIPLRI
560 570 580 590 600
SYANYRDHLN DSNLIKVQVF LQHLQSQFFF LSERDIYLLN PEIKIRILGE
610 620 630 640 650
PKQFRKLVAE LSVKNPLHVP LHDCAFTVEG AGLTQGQKIA RVPEPVEPGN
660 670 680
TVTTRMDLMP RWPGLHKLVV NFESDKMKAV KGYWNVIIG
Length:689
Mass (Da):78,203
Last modified:January 9, 2013 - v2
Checksum:i57C3293D8EC6AE01
GO

Sequence databases

RefSeqiXP_007474431.1, XM_007474369.2

Genome annotation databases

EnsembliENSMODT00000000241; ENSMODP00000000237; ENSMODG00000000203
GeneIDi100032853
KEGGimdo:100032853

Similar proteinsi

Entry informationi

Entry nameiF6TFD4_MONDO
AccessioniPrimary (citable) accession number: F6TFD4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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