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Entry version 39 (05 Jun 2019)
Sequence version 2 (09 Jan 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

CCDC141

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cell-cell adhesion mediator activity Source: GO_Central

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC141Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13616 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002280 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMODG00000010153 Expressed in 6 organ(s), highest expression level in heart

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6TAX5 baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
13616.ENSMODP00000012712

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1379 – 1467Ig-likeInterPro annotationAdd BLAST89
Domaini1475 – 1564Ig-likeInterPro annotationAdd BLAST90

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1162 – 1191DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili60 – 94Sequence analysisAdd BLAST35
Coiled coili224 – 248Sequence analysisAdd BLAST25
Coiled coili288 – 315Sequence analysisAdd BLAST28
Coiled coili331 – 358Sequence analysisAdd BLAST28
Coiled coili651 – 671Sequence analysisAdd BLAST21
Coiled coili763 – 790Sequence analysisAdd BLAST28
Coiled coili945 – 979Sequence analysisAdd BLAST35
Coiled coili992 – 1012Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFKI Eukaryota
ENOG410XSUV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000038972

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6TAX5

Identification of Orthologs from Complete Genome Data

More...
OMAi
AKEWNST

TreeFam database of animal gene trees

More...
TreeFami
TF331580

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07679 I-set, 2 hits
PF00435 Spectrin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409 IG, 2 hits
SM00408 IGc2, 2 hits
SM00150 SPEC, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6TAX5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSQESSGAL LSTTTVSSVA VQAGDSRIVI AILKCGKWVQ LQLAESCPNL
60 70 80 90 100
LEIGSSQDET KKLLEDHELL LAKLKALEDR VWDLLQEADK VAEENKDQSQ
110 120 130 140 150
VYEAMAETLG DAWAALVTVL ERRRELLKLT SEFFENALEF AMKIDQAEDF
160 170 180 190 200
LQNTQEYENA ESLKLLLQLH EHHSKEIHLL TLRRSLTLLN KSQQLTEFIE
210 220 230 240 250
KFKCDGPNVN SELIQGAHSS CLKIDSLLEL LQDRRRQLDK YLKQQRQELE
260 270 280 290 300
QVLQICQWDQ EENQVTSWFQ KTIKDLQKQH LGSSLSENEE LIQKHKELSL
310 320 330 340 350
KAKEWNSAVD KLKSEALSIL LTEDYMEKEH LQLSNHNLNQ LQEQFTQLME
360 370 380 390 400
ERKTFLQEAN DFFNSVNKAF DILGRVEACL KLLKSEGLSL PVLAARHEEL
410 420 430 440 450
HREIKDCTED ALQKGQALIS QGDSCSSRMA GIHEMMGCIQ RRVDQLAQQC
460 470 480 490 500
SAHKELALRK QQLTASMEGY LRKVATLSVQ KISPVLSSSM DLGSCLSDSE
510 520 530 540 550
QILSKYLELD SQAKETSHEL EAAIKIMKEE DTFEASEEAS LFTKAALIKD
560 570 580 590 600
ELAVLVRDIS SKVQVLQTYV AFLKSSEKVE ELSRSLKEFF KTEVTQQEKG
610 620 630 640 650
EAEFLSCVES PDTQWQLFLK ESFSAQDLGL EFLNLINMAN EDIVLKAKNV
660 670 680 690 700
IHITENMLEN QDAEREELKN LWIARQLQVN QDKSVKQQWG TFKDQLKETT
710 720 730 740 750
QNLKLLQEAL MPVSALNLGG SLHSLLHLQK KWNQMKPQFQ QLDAEVWYLL
760 770 780 790 800
KVFEVLNLKG APVKEKTQQL KDLTQLHQKQ KERRKDYENI LSKAVRFHSV
810 820 830 840 850
KEKLESLTKS GELEFFESIL EWDDTFNAKV HLRRSQEKQA HIEHLYKLAL
860 870 880 890 900
SSGMNIISAV QQPTCFNVSA KTLQQQLEIL QGDSMVWHAK ADKYEEELTR
910 920 930 940 950
ISQYCTTREE INEHRESFKD IKKKFNNLKF NYSKKTEKAR NLKVLKNQIQ
960 970 980 990 1000
QVDVYAEKIQ TLKKKMENFE IKISDSLLNY PTNKVTILLE SIRELKKQVD
1010 1020 1030 1040 1050
EFGRVVEDYK KNLDLIEHLQ ETMEECQFWC EEASATVVRV GKYSTECKTK
1060 1070 1080 1090 1100
EAIEILHKQF NKFIMPTVPQ QEERIQEITA LAKRLYGLEE GQKYAEKIIT
1110 1120 1130 1140 1150
KHQEVLESVT ELCGSLTELE QKLEEQEPEA AISIHRSIEE DQFPQEASCS
1160 1170 1180 1190 1200
TKEDSLQPLL LSEEGPSEDE SDCASPDDIS LPPLPGSPES NLLQSEMEFD
1210 1220 1230 1240 1250
ELPIQNAQSL HISSYNLQMK INDRDPRETH KPGPSAPVTF ISNCWGEAVS
1260 1270 1280 1290 1300
SPDERPLPLT PGHCPEFKAD VPLTPLEFLE KESTFRKISA RPPESMTSKV
1310 1320 1330 1340 1350
HETCLQQCHQ VHKSMLETQE QLHDNNNFTK TQDRLHANPD AFPGLLFQSD
1360 1370 1380 1390 1400
TIRSSQVTRE EIKSTSEKNS RVSLAGQAPN FSRLLSNVTV MEGSPVTLEV
1410 1420 1430 1440 1450
EVTGFPEPTL TWYKKGQKLT ADGHLKVLHK ETKHTVFIQK VCETDAGLYV
1460 1470 1480 1490 1500
ARAQNTSGTL SSSAILYVTV KGKLPKFLEK FGPTNLKEGE DLILRCTVSG
1510 1520 1530 1540 1550
RPTPNVIWSK DNVQVVAGDI NVQKLGDNYY LLKKNVILSD TGEYLCSAMN
1560 1570 1580 1590 1600
EVGEANCSAR IVVTGKGERE EINCITKTEA ESGAKFLSEC TTTNIEEQVP
1610 1620 1630 1640 1650
VTHVSQKIMT NQFSVRRFPA AGEHYQDFAV LQAGYRMIHR RKRLGMEEHH
1660 1670 1680 1690 1700
SSEKGERENR AVVTQEGLNV KRRNKKKLLE VKIKGNICDR DFEICNVKKM
1710 1720
STRMATSYGE DPSEVSENKL N
Length:1,721
Mass (Da):196,424
Last modified:January 9, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF1836DEB95B7AAE0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6TB56F6TB56_MONDO
Uncharacterized protein
CCDC141
1,716Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMODT00000012944; ENSMODP00000012712; ENSMODG00000010153

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi13616.ENSMODP00000012712

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMODT00000012944; ENSMODP00000012712; ENSMODG00000010153

Phylogenomic databases

eggNOGiENOG410IFKI Eukaryota
ENOG410XSUV LUCA
GeneTreeiENSGT00440000038972
InParanoidiF6TAX5
OMAiAKEWNST
TreeFamiTF331580

Gene expression databases

BgeeiENSMODG00000010153 Expressed in 6 organ(s), highest expression level in heart
ExpressionAtlasiF6TAX5 baseline

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PfamiView protein in Pfam
PF07679 I-set, 2 hits
PF00435 Spectrin, 1 hit
SMARTiView protein in SMART
SM00409 IG, 2 hits
SM00408 IGc2, 2 hits
SM00150 SPEC, 4 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6TAX5_MONDO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6TAX5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: June 5, 2019
This is version 39 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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