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UniProtKB - F6T845 (F6T845_HORSE)

Entry version 66 (12 Aug 2020)
Sequence version 3 (11 Dec 2019)
Previous versions | rss
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Protein
Submitted name:

Myosin XVIIIA

Gene

MYO18A

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation, Motor protein, MyosinPROSITE-ProRule annotationARBA annotation
LigandATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myosin XVIIIAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYO18AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...VGNCi		VGNC:20496, MYO18A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F6T845

PRoteomics IDEntifications database

More...PRIDEi		F6T845

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSECAG00000020855, Expressed in gluteus medius and 23 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F6T845, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini220 – 311PDZInterPro annotationAdd BLAST92
Domaini349 – 401Myosin N-terminal SH3-likeInterPro annotationAdd BLAST53
Domaini405 – 1185Myosin motorInterPro annotationAdd BLAST781
Domaini542 – 607RECA_3InterPro annotationAdd BLAST66

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 34DisorderedSequence analysisAdd BLAST34
Regioni140 – 167DisorderedSequence analysisAdd BLAST28
Regioni723 – 742DisorderedSequence analysisAdd BLAST20
Regioni1450 – 1480DisorderedSequence analysisAdd BLAST31
Regioni1852 – 1901DisorderedSequence analysisAdd BLAST50
Regioni1959 – 2054DisorderedSequence analysisAdd BLAST96

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1249 – 1304Sequence analysisAdd BLAST56
Coiled coili1312 – 1353Sequence analysisAdd BLAST42
Coiled coili1509 – 1588Sequence analysisAdd BLAST80
Coiled coili1594 – 1642Sequence analysisAdd BLAST49
Coiled coili1658 – 1678Sequence analysisAdd BLAST21
Coiled coili1713 – 1810Sequence analysisAdd BLAST98

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi140 – 164PolarSequence analysisAdd BLAST25
Compositional biasi1959 – 1985PolyampholyteSequence analysisAdd BLAST27
Compositional biasi1999 – 2014PolarSequence analysisAdd BLAST16
Compositional biasi2016 – 2031PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2034 – 2054PolarSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155768

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000192_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F6T845

Identification of Orthologs from Complete Genome Data

More...OMAi		EAWHETE

Database of Orthologous Groups

More...OrthoDBi		34123at2759

TreeFam database of animal gene trees

More...TreeFami		TF339614

Family and domain databases

Conserved Domains Database

More...CDDi		cd01386, MYSc_Myo18, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.42.10, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR031244, MYO18A
IPR001609, Myosin_head_motor_dom
IPR027401, Myosin_IQ_contain_sf
IPR004009, Myosin_N
IPR002928, Myosin_tail
IPR036064, MYSc_Myo18
IPR027417, P-loop_NTPase
IPR001478, PDZ
IPR036034, PDZ_sf
IPR020587, RecA_monomer-monomer_interface

The PANTHER Classification System

More...PANTHERi		PTHR45615:SF13, PTHR45615:SF13, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00063, Myosin_head, 2 hits
PF01576, Myosin_tail_1, 1 hit
PF00595, PDZ, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00193, MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00015, IQ, 1 hit
SM00242, MYSc, 1 hit
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50156, SSF50156, 1 hit
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS50106, PDZ, 1 hit
PS50163, RECA_3, 1 hit
PS51844, SH3_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

F6T845-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFNLMKKDKD KDGGRKEKKE KKEKKERMSA AELRSLEEMS LRRGFFNLNR 
        60         70         80         90        100
SSKRESKTRL EISNPIPIKV ASGSDLHLTD IDSDSNRGSV ILDSGHLSTA 
       110        120        130        140        150
SSSDDLKGEE GSFRGSVLQR AAKFGSLAKQ NSQMIVKRFS FSQRSRDESA 
       160        170        180        190        200
SETSTPSEHS AAPSPQVEAR TLEGQLMQHP GPGIPRPAPR SRVPELVTKR 
       210        220        230        240        250
FPADLRLPPV VPPPLPALRE LELQRRPTGD FGFSLRRTTM LDRGPEGQVY 
       260        270        280        290        300
RRVVHFAEPG AGTKDVALGL VPGDRLMEIN GHNVESKSRD EIVEMIRQSG 
       310        320        330        340        350
DSVRLKVQPI PELSELSRSW LRSGEGTRRE PANVKTEEQI AAEEAWYETE 
       360        370        380        390        400
KVWLVHKDGF SLASQLKSEE LSLPEGKVRV KLDHDGAILD VDEDDVEKAN 
       410        420        430        440        450
APSCDRLEDL ASLVYLNESS VLHTLRQRYG ASLLYTYAGP SLLVLSPRGA 
       460        470        480        490        500
PAVYSEKVMH MFKGCRREDM APHIYAVAQN AYRAMLMSRQ DQSIILLGSS 
       510        520        530        540        550
GSGKTTSCQH LVQYLATIAG TSGNKVFSVE KWQALYTLLE AFGNSPTIMN 
       560        570        580        590        600
GNATRFSQIL SLDFDQAGQV ASASIQTMLL EKLRVARRPA SEATFNIFYY 
       610        620        630        640        650
LLACGDGTLR TELHLNHLAE NNVFGIVPLA KPEEKQKAAQ QFSKLQTAMK 
       660        670        680        690        700
VLGISPDEQK ACWLILAAIY HLGAAGATKE AAEAGRKQFA RHEWAQKAAY 
       710        720        730        740        750
LLGCSLEELS SAIFKHQHKG GTLQRSTSFR QGPEESGLGD GTGPKLSALE 
       760        770        780        790        800
CLEGMASGLY SELFTLLVSL VNRALKSSQH SLCSMMIVDT PGFQNPEQGG 
       810        820        830        840        850
SARGASFEEL CHNYAQDRLQ RLFHERTFVQ ELERYKEENI ELAFDDLEPA 
       860        870        880        890        900
TDDSVAAVDQ ASHQSLVRSL ARTDEARGLL WLLEEEALVP GATEDALLER 
       910        920        930        940        950
LFSYYGPQEG DKKGQSPLLR SSKPHHFLLG HSHGTNWVEY NVAGWLSYTK 
       960        970        980        990       1000
QNPATQNAPR LLQDSQKKII SNLFLGRAGS ATVLSGSIAG LEGGSQLALR 
      1010       1020       1030       1040       1050
RATSMRKTFT TGMAAVKKKS LCIQIKLQVD ALIDTIKKSK LHFVHCFLPV 
      1060       1070       1080       1090       1100
AEGWAGEPRS ASSRRVSSSS ELDLPSGDHC EAGLLQLDVP LLRAQLRGSR 
      1110       1120       1130       1140       1150
LLDAMRMYRQ GYPDHMVFSE FRRRFDVLAP HLTKKHGRNY IVVDERRAVE 
      1160       1170       1180       1190       1200
ELLESLDLEK SSCCMGLSRV FFRAGTLARL EEQRDDQTSR NLTLFQAACR 
      1210       1220       1230       1240       1250
GFLARQHFKK RKIQDLAIRC VQKNIKKNKG VKDWPWWKLF TTVRPLIEVQ 
      1260       1270       1280       1290       1300
LSEEQIRNRD EEIQQLRSKL EKVEKERNEL RLNSDRLETR ISELTSELTD 
      1310       1320       1330       1340       1350
ERNTGESASQ LLDAETAERL RAEKEMKELQ TQYDALKKQM EVMEMEVMEA 
      1360       1370       1380       1390       1400
RLIRAAEING EVDDDDTGGE WRLKYERAVR EVDFTKKRLQ QEFEDKLEVE 
      1410       1420       1430       1440       1450
QQNKRQLERR LGDLQADSDE SQRALQQLKK KCQRLTAELQ DTKLHLEGQQ 
      1460       1470       1480       1490       1500
VRNHELEKKQ RRFDSELSQA HEEAQREKLQ REKLQREKDM LLAEAFSLKQ 
      1510       1520       1530       1540       1550
QLEEKDMDIA GFTQKVVSLE AELQDISSQE SKDEASLAKV KKQLRDLEAK 
      1560       1570       1580       1590       1600
VKDQEEELDE QAGTIQMLEQ AKLRLEMEME RMRQTHSKEM ESRDEEVEEA 
      1610       1620       1630       1640       1650
RQSCQKKLKQ MEVQLEEEYE DKQKVLREKR ELESKLTTLS DQVNQRDFES 
      1660       1670       1680       1690       1700
EKRLRKDLKR TKALLADAQI MLDHLKNNAP SKREIAQLKN QLEESEFTCA 
      1710       1720       1730       1740       1750
AAVKARKAME VEIEDLHLQI DDIAKAKTAL EEQLSRLQRE KNEIQNRLEE 
      1760       1770       1780       1790       1800
DQEDMNELMK KHKAAVAQAS RDLAQMNDLQ AQLEEANKEK QELQEKLQTL 
      1810       1820       1830       1840       1850
QSQVEFLEQS MVDKSLVSRQ EAKIRELETR LEFERTQVKR LESLASRLKE 
      1860       1870       1880       1890       1900
NMEKLTEERD QRIAAENREK EQNKRLQRQL RDTKEEMGEL ARKEAEASRK 
      1910       1920       1930       1940       1950
KHELEMDLES LEAANQSLQA DLKLAFKRIG DLQAAIEDEM ESDENEDLIN 
      1960       1970       1980       1990       2000
SLQDMVTKYQ KRKNKPEGES DVDSELEDRV DGVKSWLSKN KGPSKAASDD 
      2010       2020       2030       2040       2050
GSLKSSSPTS YWKSPAPDRS DDEHDPPDST ARPRYSHNYL SDSDTEAKPM 

ETNP
Length:2,054
Mass (Da):233,286
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA99D97D53D42F354
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2HTL6A0A3Q2HTL6_HORSE
Myosin XVIIIA
MYO18A
2,432Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I0Z1A0A3Q2I0Z1_HORSE
Myosin XVIIIA
MYO18A
2,428Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GST5A0A3Q2GST5_HORSE
Myosin XVIIIA
MYO18A
2,016Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2ICX5A0A3Q2ICX5_HORSE
Myosin XVIIIA
MYO18A
2,417Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2L723A0A3Q2L723_HORSE
Myosin XVIIIA
MYO18A
2,402Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F5Q2S5A0A5F5Q2S5_HORSE
Myosin XVIIIA
MYO18A
2,002Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F5Q4T0A0A5F5Q4T0_HORSE
Myosin XVIIIA
MYO18A
1,870Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_003362477.1, XM_003362429.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSECAT00000022672; ENSECAP00000018749; ENSECAG00000020855

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100059638

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_003362477.1, XM_003362429.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PaxDbiF6T845
PRIDEiF6T845

Genome annotation databases

EnsembliENSECAT00000022672; ENSECAP00000018749; ENSECAG00000020855
GeneIDi100059638

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		399687
VGNCiVGNC:20496, MYO18A

Phylogenomic databases

GeneTreeiENSGT00940000155768
HOGENOMiCLU_000192_1_0_1
InParanoidiF6T845
OMAiEAWHETE
OrthoDBi34123at2759
TreeFamiTF339614

Gene expression databases

BgeeiENSECAG00000020855, Expressed in gluteus medius and 23 other tissues
ExpressionAtlasiF6T845, baseline

Family and domain databases

CDDicd01386, MYSc_Myo18, 1 hit
Gene3Di2.30.42.10, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR031244, MYO18A
IPR001609, Myosin_head_motor_dom
IPR027401, Myosin_IQ_contain_sf
IPR004009, Myosin_N
IPR002928, Myosin_tail
IPR036064, MYSc_Myo18
IPR027417, P-loop_NTPase
IPR001478, PDZ
IPR036034, PDZ_sf
IPR020587, RecA_monomer-monomer_interface
PANTHERiPTHR45615:SF13, PTHR45615:SF13, 1 hit
PfamiView protein in Pfam
PF00063, Myosin_head, 2 hits
PF01576, Myosin_tail_1, 1 hit
PF00595, PDZ, 1 hit
PRINTSiPR00193, MYOSINHEAVY
SMARTiView protein in SMART
SM00015, IQ, 1 hit
SM00242, MYSc, 1 hit
SM00228, PDZ, 1 hit
SUPFAMiSSF50156, SSF50156, 1 hit
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS50106, PDZ, 1 hit
PS50163, RECA_3, 1 hit
PS51844, SH3_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6T845_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6T845
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: August 12, 2020
This is version 66 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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