UniProtKB - F6SQN2 (F6SQN2_HORSE)
Protein
Submitted name:
HHIP like 1
Gene
HHIPL1
Organism
Equus caballus (Horse)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- catalytic activity Source: InterPro
- scavenger receptor activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: HHIP like 1Imported |
Gene namesi | Name:HHIPL1Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:18776, HHIPL1 |
Subcellular locationi
Other locations
- membrane Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 27 | Sequence analysisAdd BLAST | 27 | |
ChainiPRO_5018614378 | 28 – 791 | Sequence analysisAdd BLAST | 764 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 754 ↔ 764 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotationProteomic databases
PaxDbi | F6SQN2 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000024687, Expressed in articular cartilage of joint and 18 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 682 – 785 | SRCRInterPro annotationAdd BLAST | 104 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 613 – 689 | DisorderedSequence analysisAdd BLAST | 77 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 637 – 653 | Pro-richSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the HHIP family.ARBA annotation
Keywords - Domaini
SignalSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000162083 |
HOGENOMi | CLU_012344_2_1_1 |
InParanoidi | F6SQN2 |
TreeFami | TF329059 |
Family and domain databases
Gene3Di | 2.120.10.30, 1 hit 3.10.250.10, 1 hit |
InterProi | View protein in InterPro IPR011042, 6-blade_b-propeller_TolB-like IPR018143, Folate_rcpt-like IPR012938, Glc/Sorbosone_DH IPR011041, Quinoprot_gluc/sorb_DH IPR001190, SRCR IPR017448, SRCR-like_dom IPR036772, SRCR-like_dom_sf |
Pfami | View protein in Pfam PF03024, Folate_rec, 1 hit PF07995, GSDH, 1 hit PF00530, SRCR, 1 hit |
PRINTSi | PR00258, SPERACTRCPTR |
SMARTi | View protein in SMART SM00202, SR, 1 hit |
SUPFAMi | SSF50952, SSF50952, 1 hit SSF56487, SSF56487, 1 hit |
PROSITEi | View protein in PROSITE PS00420, SRCR_1, 1 hit PS50287, SRCR_2, 1 hit |
i Sequence
Sequence statusi: Complete.
F6SQN2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XXXXXXGRRA GAGALLALLA LRALGAAAHP QCLDFRPPFR PPEPLRFCAQ
60 70 80 90 100
YSAFGCCAPE QDAALAHRFG ALAARVDADE WAACAGYALD LLCQECSPYA
110 120 130 140 150
AHLYDAEDPS TPLRTLPGLC EDYCLDMWQT CRGLIRHLSP DRELWALEDN
160 170 180 190 200
RAKFCHYLSL DDTDYCFPRL LVNENLNSNL GRVVADAKGC LQLCLEEVAN
210 220 230 240 250
GLRNPVAMVH AHDGTHRFFV AEQVGLVWAY LPDRSRLEKP FLNVSQAVLT
260 270 280 290 300
SPWEGDERGF LGIALHPGFR HNGKLYVYYS VGVDFDEWIR ISEFRVSEDD
310 320 330 340 350
MNTVDHRSER IILEIEEPAS NHNGGQLLFG DDGYLYIFTG DGGMAGDPFG
360 370 380 390 400
KFGNAQNKSA LLGKVLRIDV DRNERGPLYR IPPDNPFVGD PAARPEVYAL
410 420 430 440 450
GVRNMWRCSF DRGDPASGAG RGRLFCGDVG QNKFEEVDLV ERGRNYGWRA
460 470 480 490 500
REGFECYDRK LCNNASLDDV LPIFAYPHKL GKSVTGGYVY RGCEYPNLNG
510 520 530 540 550
LYIFGDFMSG RLMSLRENPG TGQWRYSEIC MGRGQTCEFP GLINNYYPYI
560 570 580 590 600
ISFAEDEAGE LYFMSTGVPS ATVARGVVYK VIDPSRRAPP GKCRIQPTQV
610 620 630 640 650
KVRSRLVRFV PKEKFIRRTE STPRPTARAP TNAPRRSRPT AAPPAPTPRP
660 670 680 690 700
ARPTRRPGGR RGGGRRRGRP GTADPAPSNG AVRLVRPAGL SPGRGRVEVF
710 720 730 740 750
AGGRWGTVCD DAWDTKAAAV VCRQLGFAHV VRATKRAEFG EGRALPILLD
760 770 780 790
DVRCKGGERT LLECTHAGVG THNCDHQEDA GVVCSREDPD L
Genome annotation databases
Ensembli | ENSECAT00000026640; ENSECAP00000022244; ENSECAG00000024687 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
Proteomic databases
PaxDbi | F6SQN2 |
Genome annotation databases
Ensembli | ENSECAT00000026640; ENSECAP00000022244; ENSECAG00000024687 |
Organism-specific databases
VGNCi | VGNC:18776, HHIPL1 |
Phylogenomic databases
GeneTreei | ENSGT00940000162083 |
HOGENOMi | CLU_012344_2_1_1 |
InParanoidi | F6SQN2 |
TreeFami | TF329059 |
Gene expression databases
Bgeei | ENSECAG00000024687, Expressed in articular cartilage of joint and 18 other tissues |
Family and domain databases
Gene3Di | 2.120.10.30, 1 hit 3.10.250.10, 1 hit |
InterProi | View protein in InterPro IPR011042, 6-blade_b-propeller_TolB-like IPR018143, Folate_rcpt-like IPR012938, Glc/Sorbosone_DH IPR011041, Quinoprot_gluc/sorb_DH IPR001190, SRCR IPR017448, SRCR-like_dom IPR036772, SRCR-like_dom_sf |
Pfami | View protein in Pfam PF03024, Folate_rec, 1 hit PF07995, GSDH, 1 hit PF00530, SRCR, 1 hit |
PRINTSi | PR00258, SPERACTRCPTR |
SMARTi | View protein in SMART SM00202, SR, 1 hit |
SUPFAMi | SSF50952, SSF50952, 1 hit SSF56487, SSF56487, 1 hit |
PROSITEi | View protein in PROSITE PS00420, SRCR_1, 1 hit PS50287, SRCR_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6SQN2_HORSE | |
Accessioni | F6SQN2Primary (citable) accession number: F6SQN2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | August 12, 2020 | |
This is version 48 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |