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Protein
Submitted name:

Rho guanine nucleotide exchange factor 7

Gene

ARHGEF7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 7Imported
Gene namesi
Name:ARHGEF7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiHostDB:ENSG00000102606.17
HGNCiHGNC:15607 ARHGEF7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000102606

PTM / Processingi

Proteomic databases

PeptideAtlasiF6SJA5
PRIDEiF6SJA5

Expressioni

Gene expression databases

BgeeiENSG00000102606 Expressed in 224 organ(s), highest expression level in corpus callosum
ExpressionAtlasiF6SJA5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF6SJA5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 94PHInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiKOG2070 Eukaryota
ENOG410XNNP LUCA
GeneTreeiENSGT00920000148946

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.iShow all

F6SJA5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XVLIQCAGSE EKNERYLLLF PNVLLMLSAS PRMSGFIYQG KLPTTGMTIT
60 70 80 90 100
KLEDSENHRN AFEISGSMIE RILVSCNNQQ DLQEWVEHLQ KQTKVTSVGN
110 120 130
PTIKPHSVPS HTVRTWCFSS FQTPGVASRG
Length:130
Mass (Da):14,562
Last modified:October 29, 2014 - v1
Checksum:i9FB68224A9A3AC88
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q14155ARHG7_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7 COOL1, KIAA0142, P85SPR, PAK3BP, PIXB ARHGEF7 COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314
803Annotation score:
B1ALK7B1ALK7_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
705Annotation score:
E9PDQ5E9PDQ5_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
547Annotation score:
E7EUY6E7EUY6_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
447Annotation score:
A0A2R8YG42A0A2R8YG42_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
862Annotation score:
E7ENL8E7ENL8_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
143Annotation score:
E7EU80E7EU80_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
151Annotation score:
B1ANY6B1ANY6_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
66Annotation score:
C9JDI6C9JDI6_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
61Annotation score:
C9JAD7C9JAD7_HUMAN
Rho guanine nucleotide exchange fac...
ARHGEF7
39Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139086 Genomic DNA No translation available.
AL353704 Genomic DNA No translation available.
AL390754 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000544132; ENSP00000445384; ENSG00000102606
UCSCiuc058yim.1 human

Similar proteinsi

Entry informationi

Entry nameiF6SJA5_HUMAN
AccessioniPrimary (citable) accession number: F6SJA5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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