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UniProtKB - F6SJ14 (F6SJ14_HORSE)

Entry version 59 (02 Dec 2020)
Sequence version 1 (27 Jul 2011)
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Protein
Submitted name:

Unk zinc finger

Gene

UNK

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri84 – 113C3H1-typePROSITE-ProRule annotationAdd BLAST30
Zinc fingeri124 – 154C3H1-typePROSITE-ProRule annotationAdd BLAST31
Zinc fingeri215 – 241C3H1-typePROSITE-ProRule annotationAdd BLAST27
Zinc fingeri251 – 285C3H1-typePROSITE-ProRule annotationAdd BLAST35
Zinc fingeri293 – 321C3H1-typePROSITE-ProRule annotationAdd BLAST29

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Unk zinc fingerImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UNKImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...VGNCi		VGNC:24802, UNK

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F6SJ14

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSECAG00000024672, Expressed in embryo and 23 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F6SJ14, baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini84 – 113C3H1-typeInterPro annotationAdd BLAST30
Domaini124 – 154C3H1-typeInterPro annotationAdd BLAST31
Domaini215 – 241C3H1-typeInterPro annotationAdd BLAST27
Domaini251 – 285C3H1-typeInterPro annotationAdd BLAST35
Domaini293 – 321C3H1-typeInterPro annotationAdd BLAST29

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24
Regioni239 – 266DisorderedSequence analysisAdd BLAST28
Regioni324 – 362DisorderedSequence analysisAdd BLAST39
Regioni569 – 602DisorderedSequence analysisAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili647 – 681Sequence analysisAdd BLAST35
Coiled coili696 – 723Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi242 – 256BasicSequence analysisAdd BLAST15
Compositional biasi325 – 342PolarSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the unkempt family.ARBA annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri84 – 113C3H1-typePROSITE-ProRule annotationAdd BLAST30
Zinc fingeri124 – 154C3H1-typePROSITE-ProRule annotationAdd BLAST31
Zinc fingeri215 – 241C3H1-typePROSITE-ProRule annotationAdd BLAST27
Zinc fingeri251 – 285C3H1-typePROSITE-ProRule annotationAdd BLAST35
Zinc fingeri293 – 321C3H1-typePROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159360

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_014526_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F6SJ14

Identification of Orthologs from Complete Genome Data

More...OMAi		TGQDPQF

Database of Orthologous Groups

More...OrthoDBi		720138at2759

TreeFam database of animal gene trees

More...TreeFami		TF314982

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR040594, Unkempt_Znf
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00642, zf-CCCH, 1 hit
PF18384, zf_CCCH_5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00356, ZnF_C3H1, 5 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF90229, SSF90229, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50103, ZF_C3H1, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F6SJ14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKGPGPGGS AASSAPPAAT AQVLQAQPEK PQHYTYLKEF RTEQCPLFVQ 
        60         70         80         90        100
HKCTQHRPYT CFHWHFVNQR RRRSIRRRDG TFNYSPDVYC TKYDEATGLC 
       110        120        130        140        150
PEGDECPFLH RTTGDTERRY HLRYYKTGIC IHETDSKGNC TKNGLHCAFA 
       160        170        180        190        200
HGPHDLRSPV YDIRELQAME ALQNGQTTVE GSIEGQSAGA ASHAMIEKIL 
       210        220        230        240        250
SEEPRWQETA YVLGNYKTEP CKKPPRLCRQ GYACPYYHNS KDRRRSPRKH 
       260        270        280        290        300
KYRSSPCPNV KHGDEWGDPG KCENGDSCQY CHTRTEQQFH PEIYKSTKCN 
       310        320        330        340        350
DMQQSGSCPR GPFCAFAHVE QPPLSDDLQP SSSVSSPTQP GPVLYMPSAA 
       360        370        380        390        400
GDSVPVSPSS PHAPDLSALL CRNSSLGSPS NLCGSPPGSI RKPPNLEGIV 
       410        420        430        440        450
FPGESGLAPG SYKKAPGFER EDQVGAEYLK NFKCQAKLKP HSLEPRSQEQ 
       460        470        480        490        500
PLLQPKQDML GILPVGSPLT SSISSSITSS LAATPPSPAG TSSVPGMNAN 
       510        520        530        540        550
ALPFYPTSDT VESVIESALD DLDLNEFGVA ALEKTFDNST VPHPASITIG 
       560        570        580        590        600
GSLLQSSAPV NIPGSLGSSA SFHSASPSPP VSLSSHFLQQ PQGHLSQSEN 
       610        620        630        640        650
TFLGTSASHG SLGLNGMNSS IWEHFASGSF SPGTSPAFLS GPGAAELARL 
       660        670        680        690        700
RQELDEANGT IKQWEESWKQ AKQACDAWKK EAEEAGERAS AAGAECELAR 
       710        720        730        740        750
EQRDALEVQV KKLQEELERL HSGPDPQALP TFSDLEALSL STLYSLQKQL 
       760        770        780        790        800
RAHLEQVDKA VFHMQSVKCL KCQEQNRAVL PCQHAVLCEL CAEGSECPVC 
       810
QPGRAHALQS
Length:810
Mass (Da):88,102
Last modified:July 27, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i065774D7AF7524CF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2HGF1A0A3Q2HGF1_HORSE
Unk zinc finger
UNK
776Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HC77A0A3Q2HC77_HORSE
Unk zinc finger
UNK
788Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2L6T0A0A3Q2L6T0_HORSE
Unk zinc finger
UNK
738Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_001492089.3, XM_001492039.5

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSECAT00000026663; ENSECAP00000022265; ENSECAG00000024672

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100059450

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecb:100059450

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_001492089.3, XM_001492039.5

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PaxDbiF6SJ14

Genome annotation databases

EnsembliENSECAT00000026663; ENSECAP00000022265; ENSECAG00000024672
GeneIDi100059450
KEGGiecb:100059450

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		85451
VGNCiVGNC:24802, UNK

Phylogenomic databases

GeneTreeiENSGT00940000159360
HOGENOMiCLU_014526_1_0_1
InParanoidiF6SJ14
OMAiTGQDPQF
OrthoDBi720138at2759
TreeFamiTF314982

Gene expression databases

BgeeiENSECAG00000024672, Expressed in embryo and 23 other tissues
ExpressionAtlasiF6SJ14, baseline

Family and domain databases

InterProiView protein in InterPro
IPR040594, Unkempt_Znf
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf
PfamiView protein in Pfam
PF00642, zf-CCCH, 1 hit
PF18384, zf_CCCH_5, 1 hit
SMARTiView protein in SMART
SM00356, ZnF_C3H1, 5 hits
SUPFAMiSSF90229, SSF90229, 1 hit
PROSITEiView protein in PROSITE
PS50103, ZF_C3H1, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6SJ14_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6SJ14
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: December 2, 2020
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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