UniProtKB - F6SDB4 (F6SDB4_CIOIN)
Protein
Fork-head domain-containing protein
Gene
foxm
Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 334 – 410 | Fork-headPROSITE-ProRule annotationAdd BLAST | 77 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: GO_Central
- protein kinase binding Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Source: GO_Central
- G2/M transition of mitotic cell cycle Source: GO_Central
- negative regulation of transcription by RNA polymerase II Source: GO_Central
- positive regulation of double-strand break repair Source: GO_Central
- positive regulation of transcription by RNA polymerase II Source: GO_Central
- regulation of cell cycle arrest Source: GO_Central
- regulation of cell population proliferation Source: GO_Central
- regulation of reactive oxygen species metabolic process Source: GO_Central
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Fork-head domain-containing proteinInterPro annotation |
Gene namesi | Name:foxmImported |
Organismi | Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported |
Taxonomic identifieri | 7719 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Tunicata › Ascidiacea › Enterogona › Phlebobranchia › Cionidae › Ciona |
Proteomesi |
|
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 334 – 410 | Fork-headInterPro annotationAdd BLAST | 77 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 39 – 99 | DisorderedSequence analysisAdd BLAST | 61 | |
Regioni | 472 – 514 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 549 – 582 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 667 – 705 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 842 – 871 | DisorderedSequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 54 – 99 | PolarSequence analysisAdd BLAST | 46 | |
Compositional biasi | 472 – 501 | PolarSequence analysisAdd BLAST | 30 | |
Compositional biasi | 549 – 568 | PolarSequence analysisAdd BLAST | 20 | |
Compositional biasi | 667 – 689 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 846 – 864 | PolarSequence analysisAdd BLAST | 19 |
Phylogenomic databases
GeneTreei | ENSGT00940000158804 |
HOGENOMi | CLU_325067_0_0_1 |
InParanoidi | F6SDB4 |
OMAi | IYQWIEE |
TreeFami | TF333250 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR042839, FOXM1 IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR46878, PTHR46878, 1 hit |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
i Sequence
Sequence statusi: Complete.
F6SDB4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKNCKGKHK PKACRPIILQ RKHPLPSILS SLKQTNAASM KTIDPESEVA
60 70 80 90 100
ATKTEQVAEL TSEDLSQNLP SNPMFSSEQQ PTTVKHEQQE LTSSQPWNQT
110 120 130 140 150
SAYENDIQIK SENILSNATS NPQQGNFGTF LNTQFVQCPP GSQMSNVMIK
160 170 180 190 200
QEPGSHQFVD TSQNMGIYQN HGAMKTMYHS VPNVQMSNMD PYNQTVLNEV
210 220 230 240 250
PLTTQSQYQT HGNVGQCNQF TYPYGSMSEM QAHSYAPNYY QQAIQPNAVH
260 270 280 290 300
SGQNMPQPQP SAHFQATNQL GVQMPPNARY HIQGFSSQAN FVDQAVDDSL
310 320 330 340 350
TNITWLGRMG VNNFMPVPIE RDRKVYERTE KRGRPPYSYM ALIQFAINSS
360 370 380 390 400
STGKMTLRQI YQWIEEKFPY FKSAKPGWKN SIRHNLSLHD IFVRQVTTGS
410 420 430 440 450
KASYWTLRSD LNIRPLTLDS VRGTSHHTFQ DTSNPQDPSW SLQTVMQGQK
460 470 480 490 500
PILPRLPQRP YILLPVPLIN NGTNDKDMTQ STTTVDVQTP SVYNSTPLPT
510 520 530 540 550
LHTDKDNRRL SSQDGSSFLT DSGFISDLSM FTPSNCLLNS VEKSLQKKSA
560 570 580 590 600
TSDSSPLLSQ TQVLSGKKGI TKKSRKEPLK TLNDSLNSSL NFEKNEDTSP
610 620 630 640 650
GKLLASHCSQ FLVSKQPVKK EKPKTPEFLK KSAMGLTEDS FDEMLEDLGS
660 670 680 690 700
PFKSYFTKTA EAEAFSTPRA NTGSRKRRCS WGSPESSKEV QNRIKTENEV
710 720 730 740 750
TSSNRSIRRV KSCVGDLRQN YADEVKNNLA TVKTKQVPTS TPLNKQKWQK
760 770 780 790 800
SKGCDDMNIE ENKENVMECF QQGTKHTEEH WDKDENGHHS IPSPIHSTSK
810 820 830 840 850
NPEFDFFHDL IGSVFKTPDK RSNPGSNFDN LTPERIPLCD ITQRQKPNPA
860 870 880 890 900
VKTETATTSD SLGPPPALLS PKFEPLDTSF SKLLDISGGS GTFSRMNTHF
910
SDVADLSLSW SNFSHL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EAAA01002031 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSCINT00000017891; ENSCINP00000017891; ENSCING00000008790 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EAAA01002031 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSCINT00000017891; ENSCINP00000017891; ENSCING00000008790 |
Phylogenomic databases
GeneTreei | ENSGT00940000158804 |
HOGENOMi | CLU_325067_0_0_1 |
InParanoidi | F6SDB4 |
OMAi | IYQWIEE |
TreeFami | TF333250 |
Family and domain databases
CDDi | cd00059, FH, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR001766, Fork_head_dom IPR042839, FOXM1 IPR018122, TF_fork_head_CS_1 IPR030456, TF_fork_head_CS_2 IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR46878, PTHR46878, 1 hit |
Pfami | View protein in Pfam PF00250, Forkhead, 1 hit |
PRINTSi | PR00053, FORKHEAD |
SMARTi | View protein in SMART SM00339, FH, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS00657, FORK_HEAD_1, 1 hit PS00658, FORK_HEAD_2, 1 hit PS50039, FORK_HEAD_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6SDB4_CIOIN | |
Accessioni | F6SDB4Primary (citable) accession number: F6SDB4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 18, 2012 | |
Last modified: | August 12, 2020 | |
This is version 61 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |