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Protein
Submitted name:

DNA polymerase eta

Gene

POLH

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • damaged DNA binding Source: InterPro
  • DNA-directed DNA polymerase activity Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase etaImported
Gene namesi
Name:POLHImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 20

Organism-specific databases

VGNCiVGNC:21661 POLH

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF6SCT4

Expressioni

Gene expression databases

BgeeiENSECAG00000024522 Expressed in 3 organ(s), highest expression level in liver

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000022036

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 259UmuCInterPro annotationAdd BLAST251

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili345 – 365Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2095 Eukaryota
COG0389 LUCA
GeneTreeiENSGT00530000062942
InParanoidiF6SCT4
KOiK03509
OMAiPVWEMPE
OrthoDBiEOG091G04Z9
TreeFamiTF103010

Family and domain databases

Gene3Di3.30.1490.100, 1 hit
InterProiView protein in InterPro
IPR036775 DNA_pol_Y-fam_lit_finger_sf
IPR017961 DNA_pol_Y-fam_little_finger
IPR001126 UmuC
PfamiView protein in Pfam
PF00817 IMS, 1 hit
PF11799 IMS_C, 1 hit
SUPFAMiSSF100879 SSF100879, 1 hit
PROSITEiView protein in PROSITE
PS50173 UMUC, 1 hit

Sequencei

Sequence statusi: Complete.

F6SCT4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANGQDRVIV LVDMDCFFVQ VEQRQNPHLR NKPCAVVQYT AWKGGGIVAV
60 70 80 90 100
SYEARAFGVT RSMWADEAKK LCPDLLLVEV PESRGKADLT KYREASVEVM
110 120 130 140 150
EVMSRFAMIE RASIDEAFVD LTSAVRERLQ KLQGQPISAD LLPSTYIEGL
160 170 180 190 200
PQGSTTAEGT DEKEEMRKQG LFQWLDSLQT DNTTSPDLQL TVGAVIVEEM
210 220 230 240 250
RAAIERQTGL QCSAGISHNK VLAKLACGLN KPNHQTLISH GSVPQLFSQM
260 270 280 290 300
PISKIRNLGG KLGASVIGIL GIEYMGELTQ FTESQLQSHF GEKNGSWLYA
310 320 330 340 350
MCRGIEHDPV KPRQILKSIG CCKNFPAKVA LTTQEQVQWW LLQLAQELEE
360 370 380 390 400
RLIKDRNEND RVATQLAVSL RVQGDRRLSS LRRCCALTCY DAHKMSHDAF
410 420 430 440 450
AVIRNYNVSG IQNEWSPPLT MLFLSATKFS ASTPSSCTDI TNFLSNDPSS
460 470 480 490 500
VPKVPITSSE AKIQGSGPGV TATKKATTSL ESFFQKAAEK QKVKEPSLSP
510 520 530 540 550
LTATTQDPMS DSPSKPSLPF QTSHATGTKP FFKQKSLLLK QKLLNDPSAF
560 570 580 590 600
FPPQNPQCSP KELPNDFPTE HPDCVPVCEE AVKLGSSRAT LTEMDLTQKS
610 620 630 640 650
PSQLASLTSK SALEVARKAT TTPSLLAAED QLPCEKCGSL VPVWEMPEHS
660 670 680 690 700
DYHFALELQK SFLQPYSSSN PRAVSASSPQ NKRNPKSPSA SSSKRPRPEG
710
MKTLESFFKP LTH
Length:713
Mass (Da):78,537
Last modified:July 27, 2011 - v1
Checksum:i6176366EBB1868DB
GO

Sequence databases

RefSeqiNP_001288252.1, NM_001301323.1

Genome annotation databases

EnsembliENSECAT00000026420; ENSECAP00000022036; ENSECAG00000024522
GeneIDi100067518
KEGGiecb:100067518

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiNP_001288252.1, NM_001301323.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000022036

Proteomic databases

PaxDbiF6SCT4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSECAT00000026420; ENSECAP00000022036; ENSECAG00000024522
GeneIDi100067518
KEGGiecb:100067518

Organism-specific databases

CTDi5429
VGNCiVGNC:21661 POLH

Phylogenomic databases

eggNOGiKOG2095 Eukaryota
COG0389 LUCA
GeneTreeiENSGT00530000062942
InParanoidiF6SCT4
KOiK03509
OMAiPVWEMPE
OrthoDBiEOG091G04Z9
TreeFamiTF103010

Gene expression databases

BgeeiENSECAG00000024522 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

Gene3Di3.30.1490.100, 1 hit
InterProiView protein in InterPro
IPR036775 DNA_pol_Y-fam_lit_finger_sf
IPR017961 DNA_pol_Y-fam_little_finger
IPR001126 UmuC
PfamiView protein in Pfam
PF00817 IMS, 1 hit
PF11799 IMS_C, 1 hit
SUPFAMiSSF100879 SSF100879, 1 hit
PROSITEiView protein in PROSITE
PS50173 UMUC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6SCT4_HORSE
AccessioniPrimary (citable) accession number: F6SCT4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 7, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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