UniProtKB - F6S9B5 (F6S9B5_HORSE)
Protein
Submitted name:
Zinc finger FYVE-type containing 28
Gene
ZFYVE28
Organism
Equus caballus (Horse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 1018 – 1074 | FYVE-typePROSITE-ProRule annotationAdd BLAST | 57 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger FYVE-type containing 28Imported |
Gene namesi | Name:ZFYVE28Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:51348, ZFYVE28 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000024955, Expressed in cerebellum and 18 other tissues |
ExpressionAtlasi | F6S9B5, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1018 – 1074 | FYVE-typeInterPro annotationAdd BLAST | 57 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 66 | DisorderedSequence analysisAdd BLAST | 66 | |
Regioni | 118 – 177 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 540 – 582 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 595 – 645 | DisorderedSequence analysisAdd BLAST | 51 | |
Regioni | 712 – 735 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 803 – 911 | DisorderedSequence analysisAdd BLAST | 109 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 870 – 884 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 888 – 906 | PolarSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Belongs to the lst-2 family.ARBA annotation
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 1018 – 1074 | FYVE-typePROSITE-ProRule annotationAdd BLAST | 57 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000157217 |
HOGENOMi | CLU_007360_1_0_1 |
InParanoidi | F6S9B5 |
TreeFami | TF320752 |
Family and domain databases
CDDi | cd15731, FYVE_LST2, 1 hit |
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR043269, FYVE_LST2 IPR000306, Znf_FYVE IPR017455, Znf_FYVE-rel IPR011011, Znf_FYVE_PHD IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF01363, FYVE, 1 hit |
SMARTi | View protein in SMART SM00064, FYVE, 1 hit |
SUPFAMi | SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS50178, ZF_FYVE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F6S9B5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHSARGQAKD AVLRAPPPRH ARRDLKFLGL PSAPGCPRAG SAPRAGRDAE
60 70 80 90 100
PGLGSLRRPR RAGGSRRLGA CAARAAVAEV AAEALAVSEQ RRAGALVPVS
110 120 130 140 150
IRLSNRLSVC RGLRVRPARR PQSLSGPRTC PRTCLPSARR PGSARASRPG
160 170 180 190 200
PLGAPAALPP RPPRAAAGPG RSAAEARAAG AGRAAMMNRF RKWLYKPKRS
210 220 230 240 250
DPQLLAQFYY ADEELNQVAA ELDSLDGRKD PQRCTLLVSQ FRSCQDNVLN
260 270 280 290 300
IINQIMDVCI PQDRAPRDFC VKFPEEIRHD NLAGQLWFGA ECLAAGSIIM
310 320 330 340 350
NRELESMAMR PLAKELTRSL EDVRGALRDQ ALRDLNTYTE KMREVLRHFD
360 370 380 390 400
VLFAEFELSY VSAMVPVKSP REYYVQQEVI VLFCETVERA LDFGYLTQDM
410 420 430 440 450
IDDYEPALMF TIPRLAIVCG LVVYADGPLN LDRKVEDMSE LFRPFHTLLR
460 470 480 490 500
KIRDLLQTLT EEELHTLERN LCISQDVEFP IRADTQVPPP LAPAFPEPLP
510 520 530 540 550
PEELLSAKAK NPEAELACSM QYDDQELEQL NRMVHRVGDE MSSLLSPPSA
560 570 580 590 600
CQSPAHRPGP EGSPRGESSP GSARLQPGSD EEDGRVFFMD DVEGAAEAPE
610 620 630 640 650
GPSGWAGSTR ADPQEGEQGG ERGEAGVSAP TVAEEGDLSN NNNIQDDKMW
660 670 680 690 700
AVGPNSCSCL DSRPHLDGWE VSVDDAETAE IIAHRTGGMK LSATVIFNPK
710 720 730 740 750
SPTSLDSAVT TLEAPGNGTS PSEPVAEGPE GGSHKLSAAP TNCLLNSCVC
760 770 780 790 800
CGGCGGSRED AVESVRDKCS PGSVISASYV GSAKTSAKGP AARLEEAQPA
810 820 830 840 850
LQALPTGAPD PLSSEDAPDR QEPKAPTSNK CLAHTSGPQV DAADGLRGEG
860 870 880 890 900
DGASGPQEPE AGQQDEGQPP AAREESRHGE LAKGEPQAGD SSGSTAGSSS
910 920 930 940 950
SDKTGPDAVP AATREKIRSR FHGSHDLIHR LFVCISGVAD QLQTNYASDL
960 970 980 990 1000
RSILKTLFEV MATKPETDDK EKLKKVTQTL RNAALEDCAL CQETLSSSEL
1010 1020 1030 1040 1050
ATKTHDGDLE DPPEWVPDEA CGFCTACKAP FTVIRRKHHC RSCGKIFCSR
1060 1070 1080
CSSHSAPLPR YGQVKPVRVC THCYMFHVTP FYSDKAGI
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q2LUK5 | A0A3Q2LUK5_HORSE | Zinc finger FYVE-type containing 28 | ZFYVE28 | 1,114 | Annotation score: | ||
A0A5F5PKX8 | A0A5F5PKX8_HORSE | Zinc finger FYVE-type containing 28 | ZFYVE28 | 163 | Annotation score: | ||
A0A5F5PXS5 | A0A5F5PXS5_HORSE | Zinc finger FYVE-type containing 28 | ZFYVE28 | 172 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000026932; ENSECAP00000022517; ENSECAG00000024955 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6S9B5 |
Genome annotation databases
Ensembli | ENSECAT00000026932; ENSECAP00000022517; ENSECAG00000024955 |
Organism-specific databases
VGNCi | VGNC:51348, ZFYVE28 |
Phylogenomic databases
GeneTreei | ENSGT00940000157217 |
HOGENOMi | CLU_007360_1_0_1 |
InParanoidi | F6S9B5 |
TreeFami | TF320752 |
Gene expression databases
Bgeei | ENSECAG00000024955, Expressed in cerebellum and 18 other tissues |
ExpressionAtlasi | F6S9B5, baseline |
Family and domain databases
CDDi | cd15731, FYVE_LST2, 1 hit |
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR043269, FYVE_LST2 IPR000306, Znf_FYVE IPR017455, Znf_FYVE-rel IPR011011, Znf_FYVE_PHD IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF01363, FYVE, 1 hit |
SMARTi | View protein in SMART SM00064, FYVE, 1 hit |
SUPFAMi | SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS50178, ZF_FYVE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6S9B5_HORSE | |
Accessioni | F6S9B5Primary (citable) accession number: F6S9B5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | October 7, 2020 | |
This is version 54 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |