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Protein
Submitted name:

Prostaglandin-endoperoxide synthase 1

Gene

PTGS1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin-endoperoxide synthase 1Imported
Gene namesi
Name:PTGS1Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500895555224 – 598Sequence analysisAdd BLAST575

Expressioni

Gene expression databases

BgeeiENSMMUG00000012886
ExpressionAtlasiF6S984 baseline

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 68EGF-likeInterPro annotationAdd BLAST39

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2408 Eukaryota
ENOG410XPZ3 LUCA
GeneTreeiENSGT00390000010743

Family and domain databases

Gene3Di1.10.640.10, 1 hit
InterProiView protein in InterPro
IPR029580 COX-1
IPR000742 EGF-like_dom
IPR010255 Haem_peroxidase
IPR019791 Haem_peroxidase_animal
IPR037120 Haem_peroxidase_sf
PANTHERiPTHR11903:SF6 PTHR11903:SF6, 1 hit
PfamiView protein in Pfam
PF03098 An_peroxidase, 1 hit
PF00008 EGF, 1 hit
PRINTSiPR00457 ANPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit
PS50292 PEROXIDASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

F6S984-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VSSLLLQFLL LLLLLPQLPV LLADPGAPTP VNPCCYYPCQ HQGICVRFGL
60 70 80 90 100
DRYQCDCTRT GYSGPNCTIP GLWTWLRNSL RPSPSFTHFL LTHGRWFWEF
110 120 130 140 150
VNATFIRELL MRLVLTVRSN LIPSPPTYNS AHDYISWESF SNVSYYTRIL
160 170 180 190 200
PSVPKDCPTP MGTKGKKQLP DAQLLARRFL LRRKFIPDPQ GTNLMFAFFA
210 220 230 240 250
QHFTHQFFKT SGKMGPGFTK ALGHGVDLGH IYGDNLERQY QLRLFKDGKL
260 270 280 290 300
KYQVLDGEVY PPSVEEAPVL MHYPRGTPPQ SQMAVGQEVF GLLPGLMLYA
310 320 330 340 350
TLWLREHNRV CDLLKAEHPT WGDEQLFQTT RLILIGETIR IVIEEYVQQL
360 370 380 390 400
SGYFLQLKFD PELLFGVQFQ YRNRIAMEFN HLYHWHPLMP DSFKVGSQEY
410 420 430 440 450
SYEQFLFNTS MLVDYGVEAL VDAFSRQSAG RIGGGRNMDH HVLHVAVDVI
460 470 480 490 500
RESREMRLQP FNEYRKRFGM KPYTSFQELV GEKEMAAELE ELYGDIDALE
510 520 530 540 550
FYPGLLLEKC HPNSIFGESM IEIGAPFSLK GLLGNPICSP EYWKPSTFGG
560 570 580 590
EMGFNIVKTA TLKKLVCLNT KTCPYVSFRV PDASQDDGPA VERPSTEL
Length:598
Mass (Da):68,395
Last modified:November 30, 2016 - v2
Checksum:i5922BF78BF23E4D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03014299 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMMUT00000018077; ENSMMUP00000016924; ENSMMUG00000012886

Similar proteinsi

Entry informationi

Entry nameiF6S984_MACMU
AccessioniPrimary (citable) accession number: F6S984
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: April 25, 2018
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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