Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi609 – 684Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
Taxonomic identifieri13616 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
Proteomesi
  • UP000002280 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMODG00000000830 Expressed in 8 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi13616.ENSMODP00000000987

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini609 – 684Nuclear receptorInterPro annotationAdd BLAST76
Domaini735 – 973NR LBDInterPro annotationAdd BLAST239

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
InParanoidiF6S8Q0
OMAiSKICLVC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

F6S8Q0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METKGYHSFP EGLDMERRWG QVSQSAEHSS LGSGERTDEN NYMEIVNVSC
60 70 80 90 100
VSGAIPNNST QGNSKEKHEL LPCLQQDSNQ SGILTSDIKT ELESKELSAT
110 120 130 140 150
VAESMGLYMD SIRDADFAYD QQNQQGRSLS PAKIYQNVEQ LVKFYKENGH
160 170 180 190 200
RPSTLNSVNR SLRSFISDSG NSVNGSIMRS IVKSPIMCHE KSPSVCSPLN
210 220 230 240 250
MNSSVCSPAG INSVSSTTAN FGSFPVHSPI TQGTPLPCSP NVENRSSVSH
260 270 280 290 300
SPAHASNVGS PLSSPISSMK SPISSPPSHC SVKSPVSSPN NVTMRSSVSS
310 320 330 340 350
PANINNSRCS ISSPSNTNNR STLSSPAAST VGSSICSPGN NAFSFAASAT
360 370 380 390 400
SVGSSTTQDV IPSPETNERG APEVTFPKTE EIENSISNNG VASQLNIIQY
410 420 430 440 450
IKSEPDGAFS SSCLGANSKV SSDSQFSVPV KQESAKHSCS GTSFKGNQTV
460 470 480 490 500
NPFPFMDGSY FSFMDDKDYY SLSGILGPPV PSFDGSCEGS AFPNPGLPMG
510 520 530 540 550
IKQELDDGSY YQENSLPSSA IVGVNSGGQS FHYRIGAQGT ISLSRPIGRD
560 570 580 590 600
QSFSHLSSFP PVNTLVESWK SHSDLSSRRN DGYPVLEYIP DNVSSSSLRS
610 620 630 640 650
VSTTSSRPSK ICLVCGDEAS GCHYGVVTCG SCKVFFKRAV EGQHNYLCAG
660 670 680 690 700
RNDCIIDKIR RKNCPACRLQ KCLQAGMNLG ARKSKKLGKL KGIHEEQQPQ
710 720 730 740 750
QQAPPPPPPP QSPEEGTTYI APVKEPSVNS ALVPQLSTIS RALTPSPSMV
760 770 780 790 800
LESIEPEVVY AGYDGSKPDT AENLLSTLNR LAGKQMIQVV KWAKVLPGFK
810 820 830 840 850
NLPLEDQITL IQYSWMCLSS FALSWRSYKH TNSQFLYFAP DLVFNEEKMR
860 870 880 890 900
QSAMYELCQG MHQISLQFVR LQLTFEEYTI MKVLLLLSTI PKDGLKSQVA
910 920 930 940 950
FEEMRTNYIK ELRKMVTKCP SNSGQSWQRF YQLTKLLDSM HDLVSDLLEF
960 970 980 990
CFYTFRESQA LKVEFPAMLV EIISDQLPKV ESGNAKPLYF HRK
Length:993
Mass (Da):108,237
Last modified:January 9, 2013 - v2
Checksum:i7C8A6671FB1A485D
GO

Genome annotation databases

EnsembliENSMODT00000001006; ENSMODP00000000987; ENSMODG00000000830

Similar proteinsi

Entry informationi

Entry nameiF6S8Q0_MONDO
AccessioniPrimary (citable) accession number: F6S8Q0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 59 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again