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Protein
Submitted name:

DNA-binding protein RFX5

Gene

RFX5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein RFX5Imported
Gene namesi
Name:RFX5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143390.17
HGNCiHGNC:9986 RFX5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143390

PTM / Processingi

Proteomic databases

MaxQBiF6R6G4
PeptideAtlasiF6R6G4
PRIDEiF6R6G4

Expressioni

Gene expression databases

BgeeiENSG00000143390 Expressed in 226 organ(s), highest expression level in female gonad
ExpressionAtlasiF6R6G4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF6R6G4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 165RFX-type winged-helixInterPro annotationAdd BLAST74

Phylogenomic databases

eggNOGiKOG3712 Eukaryota
ENOG410XSHE LUCA
GeneTreeiENSGT00550000074532

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR003150 DNA-bd_RFX
IPR039779 RFX-like
IPR033486 RFX5
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR12619 PTHR12619, 1 hit
PTHR12619:SF18 PTHR12619:SF18, 1 hit
PfamiView protein in Pfam
PF02257 RFX_DNA_binding, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51526 RFX_DBD, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

F6R6G4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEDEPDAKS PKTGGRAPPG GAEAGEPTTL LQRLRGTISK AVQNKVEGIL
60 70 80 90 100
QDVQKFSDND KLYLYLQLPS GPTTGDKSSE PSTLSNEEYM YAYRWIRNHL
110 120 130 140 150
EEHTDTCLPK QSVYDAYRKY CESLACCRPL STANFGKIIR EIFPDIKARR
160
LGGRGQSKYC YSGIR
Length:165
Mass (Da):18,473
Last modified:July 27, 2011 - v1
Checksum:iCBA9E814F0625812
GO

Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P48382RFX5_HUMAN
DNA-binding protein RFX5
RFX5
616Annotation score:
H0Y4B4H0Y4B4_HUMAN
DNA-binding protein RFX5
RFX5
235Annotation score:
F8W689F8W689_HUMAN
DNA-binding protein RFX5
RFX5
596Annotation score:
F6UE82F6UE82_HUMAN
DNA-binding protein RFX5
RFX5
184Annotation score:
F6X9D6F6X9D6_HUMAN
DNA-binding protein RFX5
RFX5
123Annotation score:
A0A0A0MSQ2A0A0A0MSQ2_HUMAN
DNA-binding protein RFX5
RFX5
229Annotation score:
F6S3S0F6S3S0_HUMAN
DNA-binding protein RFX5
RFX5
96Annotation score:
F8WDU3F8WDU3_HUMAN
DNA-binding protein RFX5
RFX5
42Annotation score:
F8WFE4F8WFE4_HUMAN
DNA-binding protein RFX5
RFX5
44Annotation score:
A0A0A0MSM9A0A0A0MSM9_HUMAN
DNA-binding protein RFX5
RFX5
117Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei165Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391069 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000458484; ENSP00000409187; ENSG00000143390
UCSCiuc057kva.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391069 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF6R6G4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF6R6G4
PeptideAtlasiF6R6G4
PRIDEiF6R6G4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000458484; ENSP00000409187; ENSG00000143390
UCSCiuc057kva.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000143390.17
HGNCiHGNC:9986 RFX5
OpenTargetsiENSG00000143390
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3712 Eukaryota
ENOG410XSHE LUCA
GeneTreeiENSGT00550000074532

Miscellaneous databases

ChiTaRSiRFX5 human

Gene expression databases

BgeeiENSG00000143390 Expressed in 226 organ(s), highest expression level in female gonad
ExpressionAtlasiF6R6G4 baseline and differential

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR003150 DNA-bd_RFX
IPR039779 RFX-like
IPR033486 RFX5
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR12619 PTHR12619, 1 hit
PTHR12619:SF18 PTHR12619:SF18, 1 hit
PfamiView protein in Pfam
PF02257 RFX_DNA_binding, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51526 RFX_DBD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6R6G4_HUMAN
AccessioniPrimary (citable) accession number: F6R6G4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 7, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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