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Protein
Submitted name:

Uncharacterized protein

Gene

SIK1

Organism
Ornithorhynchus anatinus (Duckbill platypus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SIK1Imported
OrganismiOrnithorhynchus anatinus (Duckbill platypus)Imported
Taxonomic identifieri9258 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMonotremataOrnithorhynchidaeOrnithorhynchus
Proteomesi
  • UP000002279 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSOANG00000006466 Expressed in 6 organ(s), highest expression level in adult mammalian kidney

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9258.ENSOANP00000010327

Structurei

3D structure databases

ProteinModelPortaliF6R3T5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 277Protein kinaseInterPro annotationAdd BLAST252
Domaini310 – 350UBAInterPro annotationAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili444 – 464Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0586 Eukaryota
ENOG410XNQ0 LUCA
GeneTreeiENSGT00900000140806
InParanoidiF6R3T5
KOiK19008
OrthoDBiEOG091G03A4
TreeFamiTF315213

Family and domain databases

CDDicd14071 STKc_SIK, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR034672 SIK
IPR015940 UBA
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50030 UBA, 1 hit

Sequencei

Sequence statusi: Complete.

F6R3T5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVIMSDFTSV PISSHIQQRP LRVGFYDIER TLGKGNFAVV KLARHRVTKT
60 70 80 90 100
QVAIKIIDKT RLDSSNLEKI YREVQIMKLL NHPHIIKLYQ VMETKDMLYI
110 120 130 140 150
VTEFAKNGEM FDYLTSNGHL SENEARKKFW QILSAVDYCH SHHIVHRDLK
160 170 180 190 200
TENLLLDANM NIKLADFGFG NFYKSGEPLS TWCGSPPYAA PEVFEGKEYE
210 220 230 240 250
GPLLDVWSLG VVLYVLVCGS LPFDGPNLPT LRQRVLEGRF RIPFFMSQDC
260 270 280 290 300
ESLIRRMLVV DPAKRITVAQ IKQHRWMQTG PALQQPQHQQ PPPPSPLCFA
310 320 330 340 350
LHGYNSNLGD YDEQVLGIMQ TLGVDRQRTV ESLQNSSYNH FAAIYYLLLE
360 370 380 390 400
RLKEHRSSQL PGRPGTTRRH RPRSSELSSF EIPPEALSSE SLRSTLLYQP
410 420 430 440 450
PQPLTQSVLQ AEMDCDLNNP LQPLFFPVDP NLNGLLRNRP ISPNSLLETT
460 470 480 490 500
ISEEVRQEKD LEEEIRAQNP FHLPGNTSRR HTLAEVTTHF YQSGPPCIVV
510 520 530 540 550
SCSASPTEGT SSDSCLPSSS TEGSGALGGR LADQVLMGNA ATVRMASPFL
560 570 580 590 600
TARSTAPVLR AQGCLGGAAL LPISFQEGRR ASDTSLTQGL KAFRQQLRKN
610 620 630 640 650
ARTKGLLGLN KIKGLARQVC QPAPARPPRS IPPAFHHSQQ TPGGYGSSSG
660 670 680 690 700
GCSREGRSLL EEILHQQRLL QWQHKPQAPA GIPPGPQPPP PTPGGPWAPG
710 720 730 740 750
SLLLSELQRE NSLELALRPA QPPLPPPFGT GVSPASSAAQ LLDAHLDLRA
760 770 780 790 800
DAPPSVTPSF PARASIALRP PGGYGPAVLS QGDCEMEDLT PAPLGKFVLV

Q
Length:801
Mass (Da):88,331
Last modified:January 9, 2013 - v2
Checksum:i7CE2046218A17E33
GO

Sequence databases

RefSeqiXP_001511894.1, XM_001511844.3

Genome annotation databases

EnsembliENSOANT00000010329; ENSOANP00000010327; ENSOANG00000006466
GeneIDi100081047
KEGGioaa:100081047

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_001511894.1, XM_001511844.3

3D structure databases

ProteinModelPortaliF6R3T5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9258.ENSOANP00000010327

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOANT00000010329; ENSOANP00000010327; ENSOANG00000006466
GeneIDi100081047
KEGGioaa:100081047

Organism-specific databases

CTDi150094

Phylogenomic databases

eggNOGiKOG0586 Eukaryota
ENOG410XNQ0 LUCA
GeneTreeiENSGT00900000140806
InParanoidiF6R3T5
KOiK19008
OrthoDBiEOG091G03A4
TreeFamiTF315213

Gene expression databases

BgeeiENSOANG00000006466 Expressed in 6 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

CDDicd14071 STKc_SIK, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR034672 SIK
IPR015940 UBA
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50030 UBA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6R3T5_ORNAN
AccessioniPrimary (citable) accession number: F6R3T5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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