UniProtKB - F6QU99 (F6QU99_HORSE)
Protein
Submitted name:
Solute carrier family 17 member 6
Gene
SLC17A6
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- L-glutamate transmembrane transporter activity Source: GO_Central
- neurotransmitter transmembrane transporter activity Source: GO_Central
- transmembrane transporter activity Source: GO_Central
GO - Biological processi
- anion transport Source: GO_Central
- neurotransmitter loading into synaptic vesicle Source: GO_Central
- regulation of synapse structure or activity Source: GO_Central
- synaptic transmission, glutamatergic Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Solute carrier family 17 member 6Imported |
Gene namesi | Name:SLC17A6Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:23052, SLC17A6 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- excitatory synapse Source: GO_Central
- integral component of membrane Source: GO_Central
- integral component of synaptic vesicle membrane Source: GO_Central
- synaptic vesicle membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 214 – 239 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 245 – 263 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 306 – 328 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 348 – 366 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 387 – 405 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 411 – 432 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 444 – 464 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 476 – 497 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSECAG00000024990, Expressed in prefrontal cortex and 5 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 70 – 502 | MFSInterPro annotationAdd BLAST | 433 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155891 |
HOGENOMi | CLU_001265_5_0_1 |
InParanoidi | F6QU99 |
TreeFami | TF313535 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
F6QU99-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESVKQRILT PGKEGLKNFA GKSLGQIYRV LEKKQETGET IELTEDGKPL
60 70 80 90 100
EVPEKKAPIC DCTCFGLPRR YIIAIMSGLG FCISFGIRCN LGVAIVDMVN
110 120 130 140 150
NSTIHRGGKV IKEKAKFNWD PETVGMIHGS FFWGYIITQI PGGYIASRLA
160 170 180 190 200
ANRVFGAAIL LTSTLNMLIP SAARVHYGCV IFVRILQGLV EGVTYPACHG
210 220 230 240 250
IWSKWAPPLE RSRLATTSFC GSYAGAVIAM PLAGILVQYT GWSSVFYVYG
260 270 280 290 300
SFGMIWYMFW LLVSYESPAK HPTITDEERR YIEESIGESA NLLGAMEKFK
310 320 330 340 350
TPWRKFFTSM PVYAIIVANF CRSWTFYLLL ISQPAYFEEV FGFEISKVGM
360 370 380 390 400
LSAVPHLVMT IIVPIGGQIA DFLRSKQILS TTTVRKIMNC GGFGMEATLL
410 420 430 440 450
LVVGYSHTRG VAISFLVLAV GFSGFAISGF NVNHLDIAPR YASILMGISN
460 470 480 490 500
GVGTLSGMVC PIIVGAMTKN KSREEWQYVF LIAALVHYGG VIFYAIFASG
510 520 530 540 550
EKQPWADPEE TSEEKCGFIH EDELDEETGD ITQNYINYGT TKSYGATTQA
560 570 580
NGGWPNGWEK KEEFVQEEGQ GSYTYKDRND YS
Genome annotation databases
Ensembli | ENSECAT00000027022; ENSECAP00000022603; ENSECAG00000024990 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6QU99 |
Genome annotation databases
Ensembli | ENSECAT00000027022; ENSECAP00000022603; ENSECAG00000024990 |
Organism-specific databases
VGNCi | VGNC:23052, SLC17A6 |
Phylogenomic databases
GeneTreei | ENSGT00940000155891 |
HOGENOMi | CLU_001265_5_0_1 |
InParanoidi | F6QU99 |
TreeFami | TF313535 |
Gene expression databases
Bgeei | ENSECAG00000024990, Expressed in prefrontal cortex and 5 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6QU99_HORSE | |
Accessioni | F6QU99Primary (citable) accession number: F6QU99 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | August 12, 2020 | |
This is version 49 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |