UniProtKB - F6QTA4 (F6QTA4_HUMAN)
Protein
Submitted name:
Cyclin-dependent kinase 19
Gene
CDK19
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein kinase activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Cyclin-dependent kinase 19Imported |
Gene namesi | Name:CDK19Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:19338, CDK19 |
VEuPathDBi | HostDB:ENSG00000155111.14 |
Expressioni
Gene expression databases
Bgeei | ENSG00000155111, Expressed in substantia nigra and 239 other tissues |
ExpressionAtlasi | F6QTA4, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 231 | Protein kinaseInterPro annotationAdd BLAST | 231 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 255 – 398 | DisorderedSequence analysisAdd BLAST | 144 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 318 – 332 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 348 – 392 | PolarSequence analysisAdd BLAST | 45 |
Phylogenomic databases
GeneTreei | ENSGT00940000158213 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 2 hits |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F6QTA4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSACREIALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF
60 70 80 90 100
HRASKANKKP MQLPRSMVKS LLYQILDGIH YLHANWVLHR DLKPANILVM
110 120 130 140 150
GEGPERGRVK IDIWAIGCIF AELLTSEPIF HCRQEDIKTS NPFHHDQLDR
160 170 180 190 200
IFSVMGFPAD KDWEDIRKMP EYPTLQKDFR RTTYANSSLI KYMEKHKVKP
210 220 230 240 250
DSKVFLLLQK LLTMDPTKRI TSEQALQDPY FQEDPLPTLD VFAGCQIPYP
260 270 280 290 300
KREFLNEDDP EEKGDKNQQQ QQNQHQQPTA PPQQAAAPPQ APPPQQNSTQ
310 320 330 340 350
TNGTAGGAGA GVGGTGAGLQ HSQDSSLNQV PPNKKPRLGP SGANSGGPVM
360 370 380 390
PSDYQHSSSR LNYQSSVQGS SQSQSTLGYS SSSQQSSQYH PSHQAHRY
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9BWU1 | CDK19_HUMAN | Cyclin-dependent kinase 19 | CDK19 CDC2L6, CDK11, KIAA1028 | 502 | Annotation score: | ||
Q5JQZ9 | Q5JQZ9_HUMAN | Cyclin-dependent kinase 19 | CDK19 | 251 | Annotation score: | ||
H0YDW9 | H0YDW9_HUMAN | Cyclin-dependent kinase 19 | CDK19 | 122 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL512430 Genomic DNA No translation available. AL603914 Genomic DNA No translation available. Z84480 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000413605; ENSP00000410604; ENSG00000155111 |
UCSCi | uc031spj.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL512430 Genomic DNA No translation available. AL603914 Genomic DNA No translation available. Z84480 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | F6QTA4 |
Protocols and materials databases
Antibodypediai | 2087, 191 antibodies |
Genome annotation databases
Ensembli | ENST00000413605; ENSP00000410604; ENSG00000155111 |
UCSCi | uc031spj.2, human |
Organism-specific databases
HGNCi | HGNC:19338, CDK19 |
OpenTargetsi | ENSG00000155111 |
VEuPathDBi | HostDB:ENSG00000155111.14 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158213 |
Miscellaneous databases
ChiTaRSi | CDK19, human |
Gene expression databases
Bgeei | ENSG00000155111, Expressed in substantia nigra and 239 other tissues |
ExpressionAtlasi | F6QTA4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 2 hits |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6QTA4_HUMAN | |
Accessioni | F6QTA4Primary (citable) accession number: F6QTA4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 29, 2014 |
Last sequence update: | October 29, 2014 | |
Last modified: | February 10, 2021 | |
This is version 34 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |