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Entry version 46 (11 Dec 2019)
Sequence version 3 (04 Feb 2015)
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Protein
Submitted name:

Glutamate-rich 3

Gene

Erich3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Glutamate-rich 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Erich3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1919095 Erich3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6QRE9

PRoteomics IDEntifications database

More...
PRIDEi
F6QRE9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000078161 Expressed in 81 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F6QRE9 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000096097

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
F6QRE9 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni145 – 192DisorderedSequence analysisAdd BLAST48
Regioni408 – 453DisorderedSequence analysisAdd BLAST46
Regioni478 – 814DisorderedSequence analysisAdd BLAST337
Regioni1111 – 1194DisorderedSequence analysisAdd BLAST84
Regioni1238 – 1445DisorderedSequence analysisAdd BLAST208
Regioni1457 – 1637DisorderedSequence analysisAdd BLAST181

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili47 – 67Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi165 – 189PolarSequence analysisAdd BLAST25
Compositional biasi408 – 451PolyampholyteSequence analysisAdd BLAST44
Compositional biasi478 – 494PolyampholyteSequence analysisAdd BLAST17
Compositional biasi495 – 523AcidicSequence analysisAdd BLAST29
Compositional biasi534 – 561PolyampholyteSequence analysisAdd BLAST28
Compositional biasi618 – 647PolyampholyteSequence analysisAdd BLAST30
Compositional biasi719 – 733PolarSequence analysisAdd BLAST15
Compositional biasi768 – 805PolyampholyteSequence analysisAdd BLAST38
Compositional biasi1111 – 1134PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1147 – 1178PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1243 – 1309PolyampholyteSequence analysisAdd BLAST67
Compositional biasi1346 – 1360PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1403 – 1429PolyampholyteSequence analysisAdd BLAST27
Compositional biasi1430 – 1444PolarSequence analysisAdd BLAST15
Compositional biasi1497 – 1520PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1550 – 1565PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1585 – 1603PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1611 – 1637PolyampholyteSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000064485

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6QRE9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027962 DUF4590

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15257 DUF4590, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F6QRE9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHSHPAGLL ATYNSLTDKH LAGYFNNTRI RRHLLRSGLI TRSGRILSEK
60 70 80 90 100
EYKVNNMKQD HQKYIRECLA RAIFHKVLDM ERYHQLEIKR KLDTLARKER
110 120 130 140 150
IQRLKGEHTR RFIEDNMPVL TPHPPAGPKT NRGHSVLAEE GRSSPLTLTA
160 170 180 190 200
PRPYTAPGNM QPPVRLQPLL SSRQTRNGSK ITSGSKPKGS LLESEALFPL
210 220 230 240 250
GGKKAMMKFR NYMDHSQKED LYQLPHINSY HTPVPPTPQP QAGKNFRDKR
260 270 280 290 300
LESWRRKRLR PITAPNGLEP LFAKDPGRIY KTAPHSNAVI TMVYFGKNVH
310 320 330 340 350
LSYDDIDFRD EIKIYQQHCG GENLCVYKGK LLEKDTFQFI SKRHHGFPFS
360 370 380 390 400
LTFFLNGIQV NRISSCCEFK HRRSTRLGGK RGYFGFVCVE KASPCYRCII
410 420 430 440 450
AMGLDRKPSS TKPKKEKITE KKEEPPNKSQ GKLRKDRMNA PSKRNEMERK
460 470 480 490 500
ESCVSAAFSA EEIKLGVKEV RTAIEEMEWK GKSGRDVWEE DQDNAVKYDY
510 520 530 540 550
EEDFEVDDEK QDEKVDEDED QADDQMSGGS KTPTESEKDN RNPEKKIETS
560 570 580 590 600
SEKAHDSENE DTGCSDSEED DRQDVKTMSS ISSRSHPYSS ESEDDSTEVG
610 620 630 640 650
GEADSVSEEG SSRSSSSQDL RENDDPGKPH FPIEKYLETE IEEQEITEGH
660 670 680 690 700
NGPWLTELSG MHVTEGKPTM GIQALSESEH KEPRRVASSE VRAKSQLQKE
710 720 730 740 750
AGLPGVEEEV GQITGGAQEP GHCCSNTAPG LSPTDDGVTP MRKPEVNLGR
760 770 780 790 800
GTEERAAISA NEQPEQDAQE MHTLKEEAMK KDESSQPEDT DAHAGVREES
810 820 830 840 850
GMQKDGTCHP QDAGIDVELR ERVDMQEDGT CHPQGADMDV GLKERVGVQE
860 870 880 890 900
DGTHYPQDAD MDVGLRERVG MQEDGTHHSQ DADMDVELKE RVGMQEDGTC
910 920 930 940 950
HPQDANMDVE LKERVGMQED GTCHPQDADM DVELEERTGM QEDGTHHPQG
960 970 980 990 1000
ADVDLGLRER AGMQEDGTCY PQNANMDVGL REKAGISEVL LGERSPTGVL
1010 1020 1030 1040 1050
LASAEQSTEK GECYLNIASE AEAGTEGSSR HGEEQLIPTG KVAAEGSVFL
1060 1070 1080 1090 1100
SVEQARDRQK DEDLDRQALL QTQMEKERAV SEAGQELKAE FTDSGGLNSE
1110 1120 1130 1140 1150
TLEEAAVLKE VGTSEVKEAE REVGSPKTDG DQGEEEALTE LEVVGPVEDT
1160 1170 1180 1190 1200
GPERKAGSEE TVLGGERAAT ERKDFLEEAP ISASTGEVQA SPREVFRGNH
1210 1220 1230 1240 1250
ELCKEDTARE GVIADTESTA EQDLRAVFPG ELAAAGGIEK VERLTPPLRE
1260 1270 1280 1290 1300
TGSEREEETG PEVLKTEDLL GEQKVKGEEE GTAKEVGSEE EDRASRPEME
1310 1320 1330 1340 1350
AHAKDVEPTG ATELGEATKL LEDPPKERAI TLSEATPQFG KSPKESEATA
1360 1370 1380 1390 1400
TEHKGGEELP GQESKALWPQ GRGLSHDGEG LLGAPGPEAD KAQGPEGFFT
1410 1420 1430 1440 1450
ARCEEWAAKE LDSSAGSERL EEDQPLQAQR EDIQRMTQGN LSGERLTRAV
1460 1470 1480 1490 1500
VVCGEAKAEN PQGEGSEDKE CPPGTVTGSL TGQNWNMGGN IVEAEEDPHG
1510 1520 1530 1540 1550
GGIEEPTAEQ KEEESAESKS ADGIPEASSA ANAQKETWDG AGEALGEAAA
1560 1570 1580 1590 1600
EERTGTEDMA PRTEKVAVVE EVTSAGAMVE TEQEQAPEAQ DREGGETKAS
1610 1620 1630
RHTGTAGEDT GSTGKDEEHQ SGAAEEFRES VSQRETA
Length:1,637
Mass (Da):180,075
Last modified:February 4, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE83A6DE361FDFC13
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8BVT3Q8BVT3_MOUSE
Glutamate-rich 3
Erich3 4922501L14Rik
517Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WS75A0A087WS75_MOUSE
Glutamate-rich 3
Erich3
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC107667 Genomic DNA No translation available.
AC125097 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000098496; ENSMUSP00000096097; ENSMUSG00000078161

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107667 Genomic DNA No translation available.
AC125097 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000096097

Proteomic databases

PaxDbiF6QRE9
PRIDEiF6QRE9

Genome annotation databases

EnsembliENSMUST00000098496; ENSMUSP00000096097; ENSMUSG00000078161

Organism-specific databases

MGIiMGI:1919095 Erich3

Phylogenomic databases

GeneTreeiENSGT00530000064485
InParanoidiF6QRE9

Miscellaneous databases

RNActiF6QRE9 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000078161 Expressed in 81 organ(s), highest expression level in testis
ExpressionAtlasiF6QRE9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027962 DUF4590
PfamiView protein in Pfam
PF15257 DUF4590, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6QRE9_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6QRE9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: February 4, 2015
Last modified: December 11, 2019
This is version 46 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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