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UniProtKB - F6QRE9 (F6QRE9_MOUSE)

Entry version 57 (25 May 2022)
Sequence version 3 (04 Feb 2015)
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Protein
Submitted name:

Glutamate-rich 3

Gene

Erich3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Glutamate-rich 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Erich3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1919095, Erich3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000078161

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F6QRE9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		368044

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000078161, Expressed in testis and 120 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000096097

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		F6QRE9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		F6QRE9

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni145 – 192DisorderedSequence analysisAdd BLAST48
Regioni408 – 453DisorderedSequence analysisAdd BLAST46
Regioni478 – 814DisorderedSequence analysisAdd BLAST337
Regioni1111 – 1194DisorderedSequence analysisAdd BLAST84
Regioni1238 – 1445DisorderedSequence analysisAdd BLAST208
Regioni1457 – 1637DisorderedSequence analysisAdd BLAST181

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili47 – 67Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi165 – 189Polar residuesSequence analysisAdd BLAST25
Compositional biasi408 – 451Basic and acidic residuesSequence analysisAdd BLAST44
Compositional biasi478 – 494Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi495 – 523Acidic residuesSequence analysisAdd BLAST29
Compositional biasi534 – 561Basic and acidic residuesSequence analysisAdd BLAST28
Compositional biasi618 – 647Basic and acidic residuesSequence analysisAdd BLAST30
Compositional biasi719 – 733Polar residuesSequence analysisAdd BLAST15
Compositional biasi768 – 805Basic and acidic residuesSequence analysisAdd BLAST38
Compositional biasi1111 – 1134Basic and acidic residuesSequence analysisAdd BLAST24
Compositional biasi1147 – 1178Basic and acidic residuesSequence analysisAdd BLAST32
Compositional biasi1243 – 1309Basic and acidic residuesSequence analysisAdd BLAST67
Compositional biasi1346 – 1360Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1403 – 1429Basic and acidic residuesSequence analysisAdd BLAST27
Compositional biasi1430 – 1444Polar residuesSequence analysisAdd BLAST15
Compositional biasi1497 – 1520Basic and acidic residuesSequence analysisAdd BLAST24
Compositional biasi1550 – 1565Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi1585 – 1603Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi1611 – 1637Basic and acidic residuesSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QVG1, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00530000064485

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004102_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F6QRE9

Identification of Orthologs from Complete Genome Data

More...OMAi		GMQEDGT

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR027962, ERICH3

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15257, DUF4590, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F6QRE9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHSHPAGLL ATYNSLTDKH LAGYFNNTRI RRHLLRSGLI TRSGRILSEK 
        60         70         80         90        100
EYKVNNMKQD HQKYIRECLA RAIFHKVLDM ERYHQLEIKR KLDTLARKER 
       110        120        130        140        150
IQRLKGEHTR RFIEDNMPVL TPHPPAGPKT NRGHSVLAEE GRSSPLTLTA 
       160        170        180        190        200
PRPYTAPGNM QPPVRLQPLL SSRQTRNGSK ITSGSKPKGS LLESEALFPL 
       210        220        230        240        250
GGKKAMMKFR NYMDHSQKED LYQLPHINSY HTPVPPTPQP QAGKNFRDKR 
       260        270        280        290        300
LESWRRKRLR PITAPNGLEP LFAKDPGRIY KTAPHSNAVI TMVYFGKNVH 
       310        320        330        340        350
LSYDDIDFRD EIKIYQQHCG GENLCVYKGK LLEKDTFQFI SKRHHGFPFS 
       360        370        380        390        400
LTFFLNGIQV NRISSCCEFK HRRSTRLGGK RGYFGFVCVE KASPCYRCII 
       410        420        430        440        450
AMGLDRKPSS TKPKKEKITE KKEEPPNKSQ GKLRKDRMNA PSKRNEMERK 
       460        470        480        490        500
ESCVSAAFSA EEIKLGVKEV RTAIEEMEWK GKSGRDVWEE DQDNAVKYDY 
       510        520        530        540        550
EEDFEVDDEK QDEKVDEDED QADDQMSGGS KTPTESEKDN RNPEKKIETS 
       560        570        580        590        600
SEKAHDSENE DTGCSDSEED DRQDVKTMSS ISSRSHPYSS ESEDDSTEVG 
       610        620        630        640        650
GEADSVSEEG SSRSSSSQDL RENDDPGKPH FPIEKYLETE IEEQEITEGH 
       660        670        680        690        700
NGPWLTELSG MHVTEGKPTM GIQALSESEH KEPRRVASSE VRAKSQLQKE 
       710        720        730        740        750
AGLPGVEEEV GQITGGAQEP GHCCSNTAPG LSPTDDGVTP MRKPEVNLGR 
       760        770        780        790        800
GTEERAAISA NEQPEQDAQE MHTLKEEAMK KDESSQPEDT DAHAGVREES 
       810        820        830        840        850
GMQKDGTCHP QDAGIDVELR ERVDMQEDGT CHPQGADMDV GLKERVGVQE 
       860        870        880        890        900
DGTHYPQDAD MDVGLRERVG MQEDGTHHSQ DADMDVELKE RVGMQEDGTC 
       910        920        930        940        950
HPQDANMDVE LKERVGMQED GTCHPQDADM DVELEERTGM QEDGTHHPQG 
       960        970        980        990       1000
ADVDLGLRER AGMQEDGTCY PQNANMDVGL REKAGISEVL LGERSPTGVL 
      1010       1020       1030       1040       1050
LASAEQSTEK GECYLNIASE AEAGTEGSSR HGEEQLIPTG KVAAEGSVFL 
      1060       1070       1080       1090       1100
SVEQARDRQK DEDLDRQALL QTQMEKERAV SEAGQELKAE FTDSGGLNSE 
      1110       1120       1130       1140       1150
TLEEAAVLKE VGTSEVKEAE REVGSPKTDG DQGEEEALTE LEVVGPVEDT 
      1160       1170       1180       1190       1200
GPERKAGSEE TVLGGERAAT ERKDFLEEAP ISASTGEVQA SPREVFRGNH 
      1210       1220       1230       1240       1250
ELCKEDTARE GVIADTESTA EQDLRAVFPG ELAAAGGIEK VERLTPPLRE 
      1260       1270       1280       1290       1300
TGSEREEETG PEVLKTEDLL GEQKVKGEEE GTAKEVGSEE EDRASRPEME 
      1310       1320       1330       1340       1350
AHAKDVEPTG ATELGEATKL LEDPPKERAI TLSEATPQFG KSPKESEATA 
      1360       1370       1380       1390       1400
TEHKGGEELP GQESKALWPQ GRGLSHDGEG LLGAPGPEAD KAQGPEGFFT 
      1410       1420       1430       1440       1450
ARCEEWAAKE LDSSAGSERL EEDQPLQAQR EDIQRMTQGN LSGERLTRAV 
      1460       1470       1480       1490       1500
VVCGEAKAEN PQGEGSEDKE CPPGTVTGSL TGQNWNMGGN IVEAEEDPHG 
      1510       1520       1530       1540       1550
GGIEEPTAEQ KEEESAESKS ADGIPEASSA ANAQKETWDG AGEALGEAAA 
      1560       1570       1580       1590       1600
EERTGTEDMA PRTEKVAVVE EVTSAGAMVE TEQEQAPEAQ DREGGETKAS 
      1610       1620       1630 
RHTGTAGEDT GSTGKDEEHQ SGAAEEFRES VSQRETA
Length:1,637
Mass (Da):180,075
Last modified:February 4, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE83A6DE361FDFC13
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8BVT3Q8BVT3_MOUSE
Glutamate-rich 3
Erich3 4922501L14Rik
517Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WS75A0A087WS75_MOUSE
Glutamate-rich 3
Erich3
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000098496.9; ENSMUSP00000096097.5; ENSMUSG00000078161.9

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

AlphaFoldDBiF6QRE9
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000096097

Proteomic databases

PaxDbiF6QRE9
ProteomicsDBi368044

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		49494, 49 antibodies from 8 providers

Genome annotation databases

EnsembliENSMUST00000098496.9; ENSMUSP00000096097.5; ENSMUSG00000078161.9

Organism-specific databases

MGIiMGI:1919095, Erich3
VEuPathDBiHostDB:ENSMUSG00000078161

Phylogenomic databases

eggNOGiENOG502QVG1, Eukaryota
GeneTreeiENSGT00530000064485
HOGENOMiCLU_004102_0_0_1
InParanoidiF6QRE9
OMAiGMQEDGT

Miscellaneous databases

RNActiF6QRE9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000078161, Expressed in testis and 120 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR027962, ERICH3
PfamiView protein in Pfam
PF15257, DUF4590, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6QRE9_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6QRE9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: February 4, 2015
Last modified: May 25, 2022
This is version 57 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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