UniProtKB - F6QQQ5 (F6QQQ5_HORSE)
Protein
Coatomer subunit zeta
Gene
COPZ1
Organism
Equus caballus (Horse)
Status
Functioni
The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.UniRule annotation
GO - Biological processi
- intracellular protein transport Source: InterPro
- retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum Source: UniProtKB-UniRule
Keywordsi
Biological process | ER-Golgi transportUniRule annotationARBA annotation, Protein transportUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Coatomer subunit zetaUniRule annotation |
Gene namesi | Name:COPZ1Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:16779, COPZ1 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane UniRule annotationARBA annotation; Peripheral membrane protein UniRule annotationARBA annotation; Cytoplasmic side UniRule annotationARBA annotation
Other locations
- Cytoplasm UniRule annotation
- COPI-coated vesicle membrane UniRule annotationARBA annotation; Peripheral membrane protein UniRule annotationARBA annotation; Cytoplasmic side UniRule annotationARBA annotation
Golgi apparatus
- COPI vesicle coat Source: UniProtKB-UniRule
- Golgi membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotation, Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSECAG00000024555, Expressed in trophectoderm and 22 other tissues |
ExpressionAtlasi | F6QQQ5, baseline |
Interactioni
Subunit structurei
Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
UniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 12 – 148 | Clat_adaptor_sInterPro annotationAdd BLAST | 137 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00390000004405 |
HOGENOMi | CLU_086803_2_0_1 |
OrthoDBi | 1522668at2759 |
TreeFami | TF300262 |
Family and domain databases
InterProi | View protein in InterPro IPR022775, AP_mu_sigma_su IPR000804, Clathrin_sm-chain_CS IPR039652, Coatomer_zeta IPR011012, Longin-like_dom_sf |
PANTHERi | PTHR11043, PTHR11043, 1 hit |
Pfami | View protein in Pfam PF01217, Clat_adaptor_s, 1 hit |
SUPFAMi | SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS00989, CLAT_ADAPTOR_S, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
F6QQQ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
LEFLLLEPSL YTVKAILILD NDGDRLFAKY YDDTYPSVKE QKAFEKNIFN
60 70 80 90 100
KTHRTDSEIA LLEGLTVVYK SSIDLYFYVI GSSYENELML MAVLNCLFDS
110 120 130 140 150
LSQMLRKNVE KRALLENMEG LFLAVDEIVD GGVILESDPQ QVVHRVALRV
160
SWGCSPPSPH LLTLHSQTC
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PKG9 | A0A5F5PKG9_HORSE | Coatomer subunit zeta | COPZ1 | 185 | Annotation score: | ||
A0A3Q2KYI9 | A0A3Q2KYI9_HORSE | Coatomer subunit zeta | COPZ1 | 177 | Annotation score: | ||
A0A5F5PLP7 | A0A5F5PLP7_HORSE | Coatomer subunit zeta | COPZ1 | 160 | Annotation score: | ||
A0A5F5PJZ6 | A0A5F5PJZ6_HORSE | Coatomer subunit zeta | COPZ1 | 164 | Annotation score: | ||
A0A5F5PRC8 | A0A5F5PRC8_HORSE | Coatomer subunit zeta | COPZ1 | 119 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000026506; ENSECAP00000022118; ENSECAG00000024555 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | F6QQQ5 |
Genome annotation databases
Ensembli | ENSECAT00000026506; ENSECAP00000022118; ENSECAG00000024555 |
Organism-specific databases
VGNCi | VGNC:16779, COPZ1 |
Phylogenomic databases
GeneTreei | ENSGT00390000004405 |
HOGENOMi | CLU_086803_2_0_1 |
OrthoDBi | 1522668at2759 |
TreeFami | TF300262 |
Gene expression databases
Bgeei | ENSECAG00000024555, Expressed in trophectoderm and 22 other tissues |
ExpressionAtlasi | F6QQQ5, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR022775, AP_mu_sigma_su IPR000804, Clathrin_sm-chain_CS IPR039652, Coatomer_zeta IPR011012, Longin-like_dom_sf |
PANTHERi | PTHR11043, PTHR11043, 1 hit |
Pfami | View protein in Pfam PF01217, Clat_adaptor_s, 1 hit |
SUPFAMi | SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS00989, CLAT_ADAPTOR_S, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6QQQ5_HORSE | |
Accessioni | F6QQQ5Primary (citable) accession number: F6QQQ5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | October 7, 2020 | |
This is version 73 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |