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Entry version 48 (05 Jun 2019)
Sequence version 2 (09 Jan 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Ornithorhynchus anatinus (Duckbill platypus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOrnithorhynchus anatinus (Duckbill platypus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9258 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMonotremataOrnithorhynchidaeOrnithorhynchus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002279 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSOANG00000008308 Expressed in 7 organ(s), highest expression level in brain

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9258.ENSOANP00000013206

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 233TOGInterPro annotationAdd BLAST233
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati169 – 207HEATPROSITE-ProRule annotationAdd BLAST39
Domaini318 – 551TOGInterPro annotationAdd BLAST234
Domaini854 – 1092TOGInterPro annotationAdd BLAST239
Domaini1302 – 1537TOGInterPro annotationAdd BLAST236

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni242 – 296DisorderedSequence analysisAdd BLAST55
Regioni548 – 631DisorderedSequence analysisAdd BLAST84
Regioni650 – 786DisorderedSequence analysisAdd BLAST137
Regioni1084 – 1129DisorderedSequence analysisAdd BLAST46
Regioni1201 – 1273DisorderedSequence analysisAdd BLAST73

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1311 – 1342Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi548 – 582PolarSequence analysisAdd BLAST35
Compositional biasi651 – 735PolarSequence analysisAdd BLAST85
Compositional biasi767 – 786PolarSequence analysisAdd BLAST20
Compositional biasi1206 – 1221PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1247 – 1273PolarSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2956 Eukaryota
ENOG410ZMY0 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155574

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6QHY0

TreeFam database of animal gene trees

More...
TreeFami
TF101155

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024395 CLASP_N_dom
IPR021133 HEAT_type_2
IPR034085 TOG

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12348 CLASP_N, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01349 TOG, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F6QHY0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEGVGLASL CGPVEQKDVG GRLQAGRDLL RYLGEPAISP DLEEDQARLH
60 70 80 90 100
HTVHQVVGWL ASSNYKVALL GLDILSAFLD RLTTRFKSYI ATVLLALIDR
110 120 130 140 150
MGDAKDQVRE QSQNLILKLM DQAASPMYIW EQLVVGFKHK NYRSREGVCL
160 170 180 190 200
CLIATLNTYG AQSLMLSKLV PHLCVLFGDS NSQVRDAAIS AVVEIYRHVG
210 220 230 240 250
EKVRIDLNKR GIPPTRLQTI FGKFDEVRNS GSMILSFSND KSFDDEESVD
260 270 280 290 300
GNKPSSAASA FKVPAPKKPG NPVNSARKPG SAGGPKSSSN TEEGGAGAVD
310 320 330 340 350
EDDFIKAFTD VPSVQIYSSR ELEETLNKIR EILSDDKHDW DQRANALKKV
360 370 380 390 400
RSLLVAGAAQ YDCFFQHLRL LDGAFKLSAK DLRSQVVREA CITVAHLSTV
410 420 430 440 450
LGNKFDHGAE AIVPTLFNLV PNSAKVMATS GCAAIRFIIR HTHVPRLIPL
460 470 480 490 500
ITSNCTSKSV AVRRRSFEFL DLLLQEWQTH SLERHAAVLV ETIKKGIHDA
510 520 530 540 550
DAEARVEARK TYMGLRNHFP GEAETLYNSL EPSYQRSLQT YLKNSGSIAS
560 570 580 590 600
LPQSDRSSSS SQESLNRPFS SKWSTASPST MAGRVSMGFK APPTPGSLQR
610 620 630 640 650
SRSDIDVNAA AGAKARHAAG QPTGSGRLGA AGLPPGSYAS LGRVRTKLST
660 670 680 690 700
PLVGIGNSKT DSRGRSRTKM VSQSQRSQSA NPIGAGSRSG SPGRVLTTTT
710 720 730 740 750
LSTMSSGVQR VLVNPASAQK RSKIPRSQGC SREASPSRLS VARGSRIPRP
760 770 780 790 800
SVSQGCSREA SRESSRDTSP VRSFQPLGSG YGIGQSSRLS SSVSAMRVLN
810 820 830 840 850
TGSDVEEAVA DALKKPARRR YESYGMYSDD DANSDASSAC SERSYSSRNG
860 870 880 890 900
SIPTYMRQTE DVAEVLNRCA SSNWSERKEG LLGLQSLLKN QRTLSRVELK
910 920 930 940 950
RLCEIFTRMF ADPHSKRVFS MFLETLVDFI QVHKDDLQDW LFVLLTQLLK
960 970 980 990 1000
KMGADLLGSV QAKVQKALDI TRESFPNDLQ FNILMRFTVD QTQTPSLKVK
1010 1020 1030 1040 1050
VAILKYIETL AQQMDPGDFV NSSETRLAVS RIITWTTEPK SSDVRKAAQS
1060 1070 1080 1090 1100
VLISLFELNT PEFTMLLGAL PKTFQDGATK LLHNHLRNTG NGSQGSMGSP
1110 1120 1130 1140 1150
LTRPASRSPA SWSSPLTSPT NTSQNTLSPR WSFLPGHCQQ DIQIHVVFTQ
1160 1170 1180 1190 1200
DSSRDTAVSR WSVGSRFLFH SAFDYDTENM NSEDIYSSLR GVTEAIQNFS
1210 1220 1230 1240 1250
FRSQEDMNEP LKRDSKKDGD GDSQQTCSGS GLLDPRAAGD AVDSGRTALD
1260 1270 1280 1290 1300
NKTSLLNTMP AHSSPRSRDY NPYNYSDNIS SFNKSALKEA MFDDDAEQFP
1310 1320 1330 1340 1350
DDLSLDHSDL VAELLKELSN HNERVEERKA ALFELMKLTQ EEAFGVWDEH
1360 1370 1380 1390 1400
FKTILLLLLE TLGDKEHSIR ALALKVLREI LRNQPRFKNY AELTIMKTLE
1410 1420 1430 1440 1450
AHKDPHKKVV RSAEEAASML ATSISPDQCI KVLCPIIQTA DYPINLAAIK
1460 1470 1480 1490 1500
MQTKVIERVS KETLTQLLPE IVPGLIQGYD NSESSVRKAC VFCLVAIHAV
1510 1520 1530 1540
IGEDLKPHLS QLTGSKMKLL NLYIKRAQSG SGGGDPATDV SGQS
Length:1,544
Mass (Da):169,518
Last modified:January 9, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFD7DD759A10D6057
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSOANT00000013209; ENSOANP00000013206; ENSOANG00000008308

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9258.ENSOANP00000013206

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOANT00000013209; ENSOANP00000013206; ENSOANG00000008308

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00940000155574
InParanoidiF6QHY0
TreeFamiTF101155

Gene expression databases

BgeeiENSOANG00000008308 Expressed in 7 organ(s), highest expression level in brain

Family and domain databases

Gene3Di1.25.10.10, 4 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024395 CLASP_N_dom
IPR021133 HEAT_type_2
IPR034085 TOG
PfamiView protein in Pfam
PF12348 CLASP_N, 2 hits
SMARTiView protein in SMART
SM01349 TOG, 4 hits
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6QHY0_ORNAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6QHY0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: June 5, 2019
This is version 48 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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