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Protein
Submitted name:

RAB GTPase activating protein 1 like

Gene

RABGAP1L

Organism
Ornithorhynchus anatinus (Duckbill platypus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • GTPase activator activity Source: GO_Central
  • Rab GTPase binding Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
RAB GTPase activating protein 1 likeImported
Gene namesi
Name:RABGAP1LImported
OrganismiOrnithorhynchus anatinus (Duckbill platypus)Imported
Taxonomic identifieri9258 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMonotremataOrnithorhynchidaeOrnithorhynchus
Proteomesi
  • UP000002279 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSOANG00000000925 Expressed in 7 organ(s), highest expression level in heart

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9258.ENSOANP00000001445

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini136 – 251PIDInterPro annotationAdd BLAST116
Domaini538 – 724Rab-GAP TBCInterPro annotationAdd BLAST187

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili807 – 926Sequence analysisAdd BLAST120
Coiled coili965 – 1020Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1102 Eukaryota
COG5210 LUCA
GeneTreeiENSGT00750000117238
InParanoidiF6QFJ5
KOiK20284
OrthoDBiEOG091G0AIH
TreeFamiTF317184

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR022164 Kinesin-like
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR033185 RabGAP1
PANTHERiPTHR22957:SF205 PTHR22957:SF205, 1 hit
PfamiView protein in Pfam
PF12473 DUF3694, 1 hit
PF00566 RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
SM00164 TBC, 1 hit
SUPFAMiSSF47923 SSF47923, 2 hits
PROSITEiView protein in PROSITE
PS01179 PID, 1 hit
PS50086 TBC_RABGAP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F6QFJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEVRTSLQKV GVSSDSVAIV NNEEFVLVPQ QADDTSVKDD EKPQLKIVSN
60 70 80 90 100
GDEQLEKAME EILRDSEKGQ SNNALDCSNI SETSRESSRE IATTPKTKPS
110 120 130 140 150
LQLILDPSNT EISTPQMPSP SELPEEHSVL FNKLTYLGCM KVSSPRSETE
160 170 180 190 200
ALRAMATMKS SSPARFPVTL YVPNDEEGSV RIIDQSGNIE IASFPIYKVL
210 220 230 240 250
FCARGHDGTL EADCFAFTES SQGTEEFQIH VFSCEIQEAV SRILYSFHTA
260 270 280 290 300
FKRSSKPVPD VKDSVLPTPD SDVFTFRVSL EVKEDDGKGN FSPVPKDRDK
310 320 330 340 350
FYFKMKQGIE KKVVITVQQL SNKELAIERC FGMLLSPGRN VKNSDMHLLD
360 370 380 390 400
MESMGKSADG RAYVITGMWN PNVPTFLALN EETPKDKRVY MTVAVDMVVT
410 420 430 440 450
EVVEPVRFLL ETVVRVYPAN ERFWYFSRKT FTETFYMKLK QSEGKGHSSV
460 470 480 490 500
GDAIYEVVSL QRESEKEEPI SPTSGGGPLS PQEDEPEEES DNELSSGTGD
510 520 530 540 550
VSKDCPEKIL YSWGELLTKW HNNLGVRPKG LSTLVKSGVP EALRAEVWQL
560 570 580 590 600
LAGCHDNQAM LDKYRLLITK DSAQESVITR DIHRTFPAHD YFKDTGGDGQ
610 620 630 640 650
ESLYKICKAY SVYDEDIGYC QGQSFLAAVL LLHMPEEQAF CVLVKIMYDY
660 670 680 690 700
GLRDLYKNNF EDLHCKFYQL ERLMQEQLPD LHSHFCDLNL EAHMYASQWF
710 720 730 740 750
LTLFTAKFPL CMVFHIIDLL LCEGLNIIFH VALALLKTSK EDLLQADFEG
760 770 780 790 800
ALKFFRVQLP KRYRAEENAR RLMEQACNIK VPTKKLKKYE KEYQTMRESQ
810 820 830 840 850
LQQEDPMDRY KRENRRLQEA SMRLEQENDD LAHELVTSKI ALRNDLDQAE
860 870 880 890 900
DKADVLNKEL LLTKQRLVET EEEKRKQEEE TAQLKEVFRK QLEKAESEIK
910 920 930 940 950
KTTAIIAEYK QICSQLSTRL EKQQAASKEE LEVVKGKVMA CKHCSEIFSK
960 970 980 990 1000
EGALKLPIIS RENEGTETDD EKDSLKKQLR EMELELAQTK LQLVEAKCKI
1010 1020 1030 1040 1050
QELEHQRGAL MNEIQAAKNS WFSKTLNSLK TATSTQPPQQ PQPSQPPRES

T
Length:1,051
Mass (Da):119,731
Last modified:January 9, 2013 - v2
Checksum:i0BB497DD37AF951E
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7FR15F7FR15_ORNAN
RAB GTPase activating protein 1 lik...
RABGAP1L
253Annotation score:

Sequence databases

RefSeqiXP_001515320.1, XM_001515270.4

Genome annotation databases

EnsembliENSOANT00000001446; ENSOANP00000001445; ENSOANG00000000925
GeneIDi100084906
KEGGioaa:100084906

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_001515320.1, XM_001515270.4

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9258.ENSOANP00000001445

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOANT00000001446; ENSOANP00000001445; ENSOANG00000000925
GeneIDi100084906
KEGGioaa:100084906

Organism-specific databases

CTDi9910

Phylogenomic databases

eggNOGiKOG1102 Eukaryota
COG5210 LUCA
GeneTreeiENSGT00750000117238
InParanoidiF6QFJ5
KOiK20284
OrthoDBiEOG091G0AIH
TreeFamiTF317184

Gene expression databases

BgeeiENSOANG00000000925 Expressed in 7 organ(s), highest expression level in heart

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR022164 Kinesin-like
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR033185 RabGAP1
PANTHERiPTHR22957:SF205 PTHR22957:SF205, 1 hit
PfamiView protein in Pfam
PF12473 DUF3694, 1 hit
PF00566 RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
SM00164 TBC, 1 hit
SUPFAMiSSF47923 SSF47923, 2 hits
PROSITEiView protein in PROSITE
PS01179 PID, 1 hit
PS50086 TBC_RABGAP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6QFJ5_ORNAN
AccessioniPrimary (citable) accession number: F6QFJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 57 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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