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Entry version 68 (02 Jun 2021)
Sequence version 3 (02 Dec 2020)
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Protein

HECT-type E3 ubiquitin transferase

Gene

HECTD1

Organism
Ornithorhynchus anatinus (Duckbill platypus)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.ARBA annotation EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.ARBA annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei2572Glycyl thioester intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseARBA annotation
Biological processUbl conjugation pathwayPROSITE-ProRule annotationARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
HECT-type E3 ubiquitin transferaseARBA annotation (EC:2.3.2.26ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HECTD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOrnithorhynchus anatinus (Duckbill platypus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9258 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMonotremataOrnithorhynchidaeOrnithorhynchus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002279 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSOANG00000014033, Expressed in female gonad and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9258.ENSOANP00000022126

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini361 – 479ANK_REP_REGIONInterPro annotationAdd BLAST119
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati395 – 427ANKPROSITE-ProRule annotationAdd BLAST33
Repeati426 – 458ANKPROSITE-ProRule annotationAdd BLAST33
Domaini1259 – 1331MIB/HERC2InterPro annotationAdd BLAST73
Domaini2144 – 2603HECTInterPro annotationAdd BLAST460

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni248 – 270DisorderedSequence analysisAdd BLAST23
Regioni450 – 506DisorderedSequence analysisAdd BLAST57
Regioni620 – 650DisorderedSequence analysisAdd BLAST31
Regioni700 – 739DisorderedSequence analysisAdd BLAST40
Regioni1357 – 1412DisorderedSequence analysisAdd BLAST56
Regioni1426 – 1476DisorderedSequence analysisAdd BLAST51
Regioni1667 – 1750DisorderedSequence analysisAdd BLAST84
Regioni1770 – 1790DisorderedSequence analysisAdd BLAST21
Regioni2290 – 2311DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1238 – 1258Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi253 – 270Polar residuesSequence analysisAdd BLAST18
Compositional biasi450 – 505Basic and acidic residuesSequence analysisAdd BLAST56
Compositional biasi725 – 739Polar residuesSequence analysisAdd BLAST15
Compositional biasi1357 – 1394Polar residuesSequence analysisAdd BLAST38
Compositional biasi1428 – 1448Polar residuesSequence analysisAdd BLAST21
Compositional biasi1668 – 1693Acidic residuesSequence analysisAdd BLAST26
Compositional biasi1694 – 1714Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1736 – 1750Basic and acidic residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPL family. K-HECT subfamily.ARBA annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4276, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156572

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000869_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6Q9Q6

Database of Orthologous Groups

More...
OrthoDBi
34110at2759

TreeFam database of animal gene trees

More...
TreeFami
TF323674

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00078, HECTc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
1.25.40.20, 1 hit
2.30.30.920, 1 hit
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR041200, FKBP3_BTHB
IPR008979, Galactose-bd-like_sf
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR010606, Mib_Herc2
IPR037252, Mib_Herc2_sf
IPR012919, SUN_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18410, BTHB, 1 hit
PF00632, HECT, 1 hit
PF06701, MIB_HERC2, 1 hit
PF07738, Sad1_UNC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 3 hits
SM00119, HECTc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF159034, SSF159034, 1 hit
SSF48371, SSF48371, 1 hit
SSF48403, SSF48403, 1 hit
SSF49785, SSF49785, 1 hit
SSF56204, SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50237, HECT, 1 hit
PS51416, MIB_HERC2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F6Q9Q6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADVDPDTLL EWLQMGQGDE RDMQLIALEQ LCMLLLMSDN VDRCFETCPP
60 70 80 90 100
RTFLPALCKI FLDESAPDNV LEVTARAITY YLDVSAECTR RIVGVDGAIK
110 120 130 140 150
ALCNRLVVVE LNNRTSRDLA EQCVKVLELI CTRESGAVFE AGGLNCVLTF
160 170 180 190 200
IRDSGHLVHK DTLHSAMAVV SRLCGKMEPQ DSSLEICVES LSSLLKHEDH
210 220 230 240 250
QVSDGALRCF ASLADRFTRR GVDPAPLAKH GLTEELLSRM AAAGGAVSGP
260 270 280 290 300
SSACKPGRST TGAPSTAADS KLSNQVSTIV SLLSTLCRGS PVVTHDLLRS
310 320 330 340 350
ELPDSIESAL QGDERCVLDT MRLVDLLLVL LFEGRKALPK SSAGSTGRIP
360 370 380 390 400
GLRRLDSSGE RSHRQLIDCI RSKDTDALID AIDTGAFEVN FMDDVGQTLL
410 420 430 440 450
NWASAFGTQE MVEFLCERGA DVNRGQRSSS LHYAACFGRP QVAKTLLRHG
460 470 480 490 500
ANPDLRDEDG KTPLDKARER GHSEVVDWMC PVNKGDDKKK KDANKDEEEC
510 520 530 540 550
NEPKGDPEMA PIYLKRLLPV FAQTFQQTML PSIRKASLAL IRKMIHFCSE
560 570 580 590 600
ALLKEVCDSD AGHNLPTILV EITATILDQE DDDDGHLLAL QIIRDLVDKG
610 620 630 640 650
GDLFLDQLAR LGVISKVSTL AGPSSDDENE EESKPEKEDE PQEDAKELQQ
660 670 680 690 700
GKPYHWRDWS IIRGRDCLYI WSDAAALELS NGSNGWFRFI LDGKLATMYS
710 720 730 740 750
SGSPEGGSDS SESRSEFLEK LQRARSQVKP STSSQPILSA PGPIKLTVGN
760 770 780 790 800
WSLTCLKEGE IAIHNSDGQQ ATILKEDLPG FVFESNRGTK HSFTAETSLG
810 820 830 840 850
SEFVTGWTGK RGRKLKSKLE KTKQKVRTMA RDLYDDHFKA VESMPRGVVV
860 870 880 890 900
TLRNIATQLE SSWELHTNRQ CIEGENTWRD LMKTALENLI VLLKDENTIS
910 920 930 940 950
PYEMCSSGLV QALLTVLNNS MDLDMKQDCT QLVERINVFK TAFSENEDDE
960 970 980 990 1000
SRPAVALIRK LIAVLESIER LPLHLYDTPG STYNLQILTR RLRFRLERAS
1010 1020 1030 1040 1050
GETSLIDRTG RMLKMEPLAT VESLEQYLLK MVAKQWYDFD RSSFVFVRKL
1060 1070 1080 1090 1100
REGQTFIFRH QHDFDENGII YWIGTNAKTA YEWVNPAAYG LVVVTSSEGR
1110 1120 1130 1140 1150
NLPYGRLEDI LSRDSSALNC HSNDDKNAWF AIDLGLWVIP SAYTLRHARG
1160 1170 1180 1190 1200
YGRSALRNWV FQVSKDGQNW TTLYTHVDDC SLNEPGSTAT WPLDPPKDEK
1210 1220 1230 1240 1250
QGWRHVRIKQ MGKNASGQTH YLSLSGFELY GTVSGVCEDQ LGKAAKEAEA
1260 1270 1280 1290 1300
NLRRQRRLVR SQVLKYMVPG ARVIRGIDWK WRDQDGSPQG EGTVTGELHN
1310 1320 1330 1340 1350
GWIDVTWDAG GSNSYRMGAE GKFDLKLAPG YDPDTAASPK PVSSTVSGTT
1360 1370 1380 1390 1400
QSWSSLVKNN CPDKTSAAAG SSSRKGSSSS VCSVASSSDI SLGSTKMERR
1410 1420 1430 1440 1450
SESVTEQSVV SGPDVHEPIV VLSSAENVPQ AEVGSSSSAS TSTLTAEAGC
1460 1470 1480 1490 1500
ENAERKLGPE SSVRTPGETS AISMGIVSVS SPDVSSVSEL TNKEAASQRP
1510 1520 1530 1540 1550
LSSSASNRLS VSSLLAAGAP MSSSASVPNL SSRETSSLES FVRRVANIAR
1560 1570 1580 1590 1600
TNATNNMNLS RSSSDNNTNT LGRNVMSTAT SPLMGAQSFP NLTTTGTTST
1610 1620 1630 1640 1650
VTMSTSSVTS SSNVATATTV LSVGQSLSNT LTTSLTSTSS ESDTGQEAEY
1660 1670 1680 1690 1700
SLYDFLDSCR ASTLLAELDD DEDLPEPDEE DDENEDDNQE DQEYEEVMIL
1710 1720 1730 1740 1750
RRPSLQRRAG SRSDVTHHAV TSQLPQVPAG AGSRPIGEQE EEEYETKGGR
1760 1770 1780 1790 1800
RRTWDDDYVL KRQFSALVPA FDPRPGRTNV QQTTDLEIPP PGTPHSELLE
1810 1820 1830 1840 1850
EVECTPSPRL ALTLKVTGLG TTREVELPLS NFRSTIFYYV QKLLQFSCNG
1860 1870 1880 1890 1900
SVKSDKLRRI WEPTYTIMYR EMKDSDKEKE SGKMGCWSIE HVEQFLGTDE
1910 1920 1930 1940 1950
LPKNDLITYL QKNADSAFLR HWKLTGTNKS IRKNRNCSQL IAAYKDFCEH
1960 1970 1980 1990 2000
GSKSGLSQGA ISTLQNCDIL SLVKEQPQAK AGNGQNSCGV EDVLQLLRIL
2010 2020 2030 2040 2050
YIVASDPYTR TSHEEGDEQL QFHFPPDEFT SKKLTTKILQ QIEEPLALAS
2060 2070 2080 2090 2100
GALPDWCEQL TSKCPFLIPF ETRQLYFTCT AFGASRAIVW LQNRREATVE
2110 2120 2130 2140 2150
RTRTTSTVRR DDPGEFRVGR LKHERVKVPR GESLMEWAEN VMQIHADRKS
2160 2170 2180 2190 2200
VLEVEFLGEE GTGLGPTLEF YALVAAEFQR TELGTWLCDD DFPDDESRHV
2210 2220 2230 2240 2250
DLGGGLKPPG YYVQRSCGLF TAPFPQDSDE LERITKLFHF LGIFLAKCIQ
2260 2270 2280 2290 2300
DNRLVDLPIS KPFFKLMCMG DIKSNMSKLI YESRGDRDLH CTESQSEAST
2310 2320 2330 2340 2350
EEGHDSLSVG SFEEDSKSEF ILDPPKPKPP AWFNGILTWE DFELVNPHRA
2360 2370 2380 2390 2400
RFLKEIKDLA IKRRQILSNK SLSEDEKNTK LQDLMLKNPS GSGPSLSIED
2410 2420 2430 2440 2450
LGLNFQFCPS SRVYGFTAVD LKPSGEDEMI TMDNAEEYVD LMFDFCMQTG
2460 2470 2480 2490 2500
IQKQMDAFRD GFNKVFPMEK LSSFSHEEVQ MILCGNQSPS WAAEDIINYT
2510 2520 2530 2540 2550
EPKLGYTRDS PGFLRFVRVL CGMSSDERKA FLQFTTGCST LPPGGLANLH
2560 2570 2580 2590 2600
PRLTVVRKVD ATDASYPSVN TCVHYLKLPE YSSEEIMRER LLAATMEKGF

HLN
Length:2,603
Mass (Da):288,590
Last modified:December 2, 2020 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i63775A23FC2179D1
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_001512305.1, XM_001512255.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSOANT00000022130; ENSOANP00000022126; ENSOANG00000014033

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_001512305.1, XM_001512255.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9258.ENSOANP00000022126

Genome annotation databases

EnsembliENSOANT00000022130; ENSOANP00000022126; ENSOANG00000014033

Phylogenomic databases

eggNOGiKOG4276, Eukaryota
GeneTreeiENSGT00940000156572
HOGENOMiCLU_000869_0_0_1
InParanoidiF6Q9Q6
OrthoDBi34110at2759
TreeFamiTF323674

Enzyme and pathway databases

UniPathwayiUPA00143

Gene expression databases

BgeeiENSOANG00000014033, Expressed in female gonad and 9 other tissues

Family and domain databases

CDDicd00078, HECTc, 1 hit
Gene3Di1.25.10.10, 1 hit
1.25.40.20, 1 hit
2.30.30.920, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR041200, FKBP3_BTHB
IPR008979, Galactose-bd-like_sf
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR010606, Mib_Herc2
IPR037252, Mib_Herc2_sf
IPR012919, SUN_dom
PfamiView protein in Pfam
PF18410, BTHB, 1 hit
PF00632, HECT, 1 hit
PF06701, MIB_HERC2, 1 hit
PF07738, Sad1_UNC, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 3 hits
SM00119, HECTc, 1 hit
SUPFAMiSSF159034, SSF159034, 1 hit
SSF48371, SSF48371, 1 hit
SSF48403, SSF48403, 1 hit
SSF49785, SSF49785, 1 hit
SSF56204, SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50237, HECT, 1 hit
PS51416, MIB_HERC2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6Q9Q6_ORNAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6Q9Q6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 2, 2020
Last modified: June 2, 2021
This is version 68 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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