UniProtKB - F6PXU1 (F6PXU1_HORSE)
Protein
Submitted name:
BCL2 like 14
Gene
BCL2L14
Organism
Equus caballus (Horse)
Status
Functioni
GO - Biological processi
- apoptotic process Source: UniProtKB-KW
- regulation of extrinsic apoptotic signaling pathway Source: GO_Central
Keywordsi
Biological process | ApoptosisARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: BCL2 like 14Imported |
Gene namesi | Name:BCL2L14Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:15794, BCL2L14 |
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSECAG00000024880, Expressed in testis and 13 other tissues |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 121 – 147 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 165 – 206 | DisorderedSequence analysisAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 125 – 147 | PolarSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Belongs to the Bcl-2 family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000154318 |
HOGENOMi | CLU_073095_0_0_1 |
InParanoidi | F6PXU1 |
OMAi | EIVHSWP |
OrthoDBi | 1288548at2759 |
TreeFami | TF336214 |
Family and domain databases
Gene3Di | 1.10.437.10, 1 hit |
InterProi | View protein in InterPro IPR002475, Bcl2-like IPR033229, BCL2L14 IPR036834, Blc2-like_sf |
PANTHERi | PTHR14965:SF1, PTHR14965:SF1, 1 hit |
SUPFAMi | SSF56854, SSF56854, 1 hit |
PROSITEi | View protein in PROSITE PS50062, BCL2_FAMILY, 1 hit |
i Sequence
Sequence statusi: Complete.
F6PXU1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCTTSACDLE EIPLDDDDPN SIEFKILAFY VKQHVFKNTS TVISPKPLRT
60 70 80 90 100
RSLSQKVVAS CSENDSWTQV PWPCRNSKSS EKTINLAKKK SSWRTLFGVI
110 120 130 140 150
EKGEDAQSSP TEVYAQGRGV AEYQGPRSRQ SSRSLSNVEQ SSENEAVDPK
160 170 180 190 200
VVSIANRVAE IVYSWPPPEE PRKNGRRAKL DGSIKLGYPP QPECSQSTAA
210 220 230 240 250
SAKKDEEDQN IAKIVELLKY SGDQLQRELE REKGLMNSFQ DGLAYSDFKT
260 270 280 290 300
ITDQFLRGVD TRGESEVKAQ SFKAALAIDV MAKLTAIDNH PMNRVLGFGT
310 320
KYLKENFSPW VQQHGGWEKV FGISHEELD
Sequence databases
RefSeqi | XP_005611004.1, XM_005610947.2 |
Genome annotation databases
Ensembli | ENSECAT00000026845; ENSECAP00000022435; ENSECAG00000024880 |
GeneIDi | 100063375 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_005611004.1, XM_005610947.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6PXU1 |
Genome annotation databases
Ensembli | ENSECAT00000026845; ENSECAP00000022435; ENSECAG00000024880 |
GeneIDi | 100063375 |
Organism-specific databases
CTDi | 79370 |
VGNCi | VGNC:15794, BCL2L14 |
Phylogenomic databases
GeneTreei | ENSGT00940000154318 |
HOGENOMi | CLU_073095_0_0_1 |
InParanoidi | F6PXU1 |
OMAi | EIVHSWP |
OrthoDBi | 1288548at2759 |
TreeFami | TF336214 |
Gene expression databases
Bgeei | ENSECAG00000024880, Expressed in testis and 13 other tissues |
Family and domain databases
Gene3Di | 1.10.437.10, 1 hit |
InterProi | View protein in InterPro IPR002475, Bcl2-like IPR033229, BCL2L14 IPR036834, Blc2-like_sf |
PANTHERi | PTHR14965:SF1, PTHR14965:SF1, 1 hit |
SUPFAMi | SSF56854, SSF56854, 1 hit |
PROSITEi | View protein in PROSITE PS50062, BCL2_FAMILY, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6PXU1_HORSE | |
Accessioni | F6PXU1Primary (citable) accession number: F6PXU1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | July 27, 2011 | |
Last modified: | February 10, 2021 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |