UniProtKB - F6NGD6 (F6NGD6_DANRE)
Protein
Submitted name:
Zgc:101540
Gene
zgc:101540
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- fatty acid transmembrane transporter activity Source: InterPro
- long-chain fatty acid-CoA ligase activity Source: GO_Central
- long-chain fatty acid transporter activity Source: GO_Central
- very long-chain fatty acid-CoA ligase activity Source: InterPro
GO - Biological processi
- bile acid biosynthetic process Source: InterPro
Enzyme and pathway databases
Reactomei | R-DRE-159418, Recycling of bile acids and salts R-DRE-193368, Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-DRE-193775, Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-DRE-389599, Alpha-oxidation of phytanate R-DRE-6798695, Neutrophil degranulation R-DRE-9033241, Peroxisomal protein import |
Names & Taxonomyi
Protein namesi | Submitted name: Zgc:101540Imported |
Gene namesi | ORF Names:zgc:101540Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-041212-67, zgc:101540 |
Subcellular locationi
Other locations
- integral component of membrane Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_5003338925 | 25 – 616 | Sequence analysisAdd BLAST | 592 |
Proteomic databases
PaxDbi | F6NGD6 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000100731, Expressed in liver and 22 other tissues |
ExpressionAtlasi | F6NGD6, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 55 – 483 | AMP-bindingInterPro annotationAdd BLAST | 429 | |
Domaini | 495 – 567 | AMP-binding_CInterPro annotationAdd BLAST | 73 |
Sequence similaritiesi
Belongs to the ATP-dependent AMP-binding enzyme family.ARBA annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG1179, Eukaryota |
GeneTreei | ENSGT00940000157947 |
HOGENOMi | CLU_000022_46_2_1 |
OMAi | FIRIQPC |
OrthoDBi | 298283at2759 |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR025110, AMP-bd_C IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf IPR030302, FATP5 |
PANTHERi | PTHR43107:SF4, PTHR43107:SF4, 1 hit |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit PF13193, AMP-binding_C, 1 hit |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6NGD6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFWYTVSAVI LLIALRLKCP YIISQTKYMC RVALAVYRTT KYIKSKPFYT
60 70 80 90 100
ILDRFQDSVR KNPKKAFIRF LDQTYSYEQS DKESNKIART LLKHADLHEG
110 120 130 140 150
DTVALLLGNE PMFLWIWLGL AKIGCSVALL NHNIRSKSLL HCFTCCGANV
160 170 180 190 200
LIAGADLQDA VEEVLPALRE QGISIYILTE HVSSEGMTSL TDKIKQASDQ
210 220 230 240 250
PIPTDLRANV AFNTPAAYIY TSGTTGLPKA AVITHRRLWA MAFFQSICGV
260 270 280 290 300
KSDDVIYVCL PLYHSSGFGL GFGGSVERGA TIVLRSKFSS SQFWDDCRKY
310 320 330 340 350
NVTVIQYIGE TMRYLCNMPK CVSDQVHNVR MAIGNGIRPD IWRTFINRFG
360 370 380 390 400
HVEIKEFYGS TEGTLGFLNY AGKIGAVGTV NSFHKKLYPY VFIKFDHEKE
410 420 430 440 450
EPVRNADGFC IEVAKGETGL LVTRLTQKIE FSGYARDPKQ TEKKKLHDVF
460 470 480 490 500
EKGDVYFNTG DLFRTDRENF IYFQDRVGDT FRWKGENVST NEVSDIMTLV
510 520 530 540 550
PCIEEANVYG VTVPGFEGRI GMAAIILKKD HQFECDDVFN HVTSYLPVYA
560 570 580 590 600
RPRFIRIQSS LAVTCTFKQL KGRLVEEGFN PALITDPLFI LDETVKSYRP
610
LTHDTYESIL DARFRL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8Q291 | A0A2R8Q291_DANRE | Zgc:101540 | zgc:101540 | 614 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU372926 Genomic DNA No translation available. CU633526 Genomic DNA No translation available. |
RefSeqi | XP_001336957.1, XM_001336921.5 |
Genome annotation databases
Ensembli | ENSDART00000086334; ENSDARP00000080769; ENSDARG00000100731 |
GeneIDi | 100004228 |
KEGGi | dre:100004228 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU372926 Genomic DNA No translation available. CU633526 Genomic DNA No translation available. |
RefSeqi | XP_001336957.1, XM_001336921.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000080769 |
Proteomic databases
PaxDbi | F6NGD6 |
Genome annotation databases
Ensembli | ENSDART00000086334; ENSDARP00000080769; ENSDARG00000100731 |
GeneIDi | 100004228 |
KEGGi | dre:100004228 |
Organism-specific databases
CTDi | 100004228 |
ZFINi | ZDB-GENE-041212-67, zgc:101540 |
Phylogenomic databases
eggNOGi | KOG1179, Eukaryota |
GeneTreei | ENSGT00940000157947 |
HOGENOMi | CLU_000022_46_2_1 |
OMAi | FIRIQPC |
OrthoDBi | 298283at2759 |
Enzyme and pathway databases
Reactomei | R-DRE-159418, Recycling of bile acids and salts R-DRE-193368, Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-DRE-193775, Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-DRE-389599, Alpha-oxidation of phytanate R-DRE-6798695, Neutrophil degranulation R-DRE-9033241, Peroxisomal protein import |
Gene expression databases
Bgeei | ENSDARG00000100731, Expressed in liver and 22 other tissues |
ExpressionAtlasi | F6NGD6, baseline |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR025110, AMP-bd_C IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, AMP-dep_Synthh-like_sf IPR030302, FATP5 |
PANTHERi | PTHR43107:SF4, PTHR43107:SF4, 1 hit |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit PF13193, AMP-binding_C, 1 hit |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6NGD6_DANRE | |
Accessioni | F6NGD6Primary (citable) accession number: F6NGD6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 26, 2013 |
Last sequence update: | June 26, 2013 | |
Last modified: | February 10, 2021 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |