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Protein

Glucose-6-phosphate isomerase

Gene

pgiB

Organism
Mycoplasma haemofelis (strain Ohio2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgiB)
  3. 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei419UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMHAE859194:G1GR7-11-MONOMER
UniPathwayi
UPA00109;UER00181

UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiBImported
Synonyms:pgiUniRule annotation
Ordered Locus Names:MHF_0011Imported
OrganismiMycoplasma haemofelis (strain Ohio2)Imported
Taxonomic identifieri859194 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000007952 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi859194.MHF_0011

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107QYV Bacteria
COG0166 LUCA
KOiK01810
OMAiVERCKAM
OrthoDBiPOG091H0EIM

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

F6FJB3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLKFKTDFL LDSTKDLIVD KYKDRIKEIF SLVSSKKALG SEMTGWIDWV
60 70 80 90 100
NKDHSKLIDD VTSIRSEWLN NGVETVVIVG TGGSYIGCRA ALNFVNNGFK
110 120 130 140 150
KNNFEFVFVP SFSERYLGEL LDSLKSKKFG IVVISKSGTT LESSVAFRFL
160 170 180 190 200
RDLLFSKEGE NYGKYIIAVT DRSKGVLRSL ADKRGIRSFI IEDDIGGRYS
210 220 230 240 250
ALTSVGLVPM ILSGIDVKRV LSGAKKSCEE NFIGEIGDNS AALYACIRHF
260 270 280 290 300
LFEDKQKVYE CIASYDPQLD FTLEKIKQLF AESEGKKGKG LMPVLLNFTP
310 320 330 340 350
DLHSVGQLLQ DGYKAFFTTI VLVSKPKYDL CISKSQFEND DGLDWLLGKS
360 370 380 390 400
LKEINGCACN GTLDAHSNVG KINNLVIELE SWEPEVFGYF YFWLCLVAMF
410 420
SSYLFEVNPF DQPGVEAYKK RMFDLLGKN
Length:429
Mass (Da):48,225
Last modified:July 27, 2011 - v1
Checksum:i87BC9E2D600D2AC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002808 Genomic DNA Translation: AEG72332.1

Genome annotation databases

EnsemblBacteriaiAEG72332; AEG72332; MHF_0011
KEGGimhf:MHF_0011

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002808 Genomic DNA Translation: AEG72332.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi859194.MHF_0011

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEG72332; AEG72332; MHF_0011
KEGGimhf:MHF_0011

Phylogenomic databases

eggNOGiENOG4107QYV Bacteria
COG0166 LUCA
KOiK01810
OMAiVERCKAM
OrthoDBiPOG091H0EIM

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00181

UPA00138

BioCyciMHAE859194:G1GR7-11-MONOMER

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6FJB3_MYCHI
AccessioniPrimary (citable) accession number: F6FJB3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 18, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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