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Protein

Ribonuclease H

Gene

rnhA

Organism
Agrobacterium sp. ATCC 31749
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Magnesium 1UniRule annotation1
Metal bindingi9Magnesium 2UniRule annotation1
Metal bindingi47Magnesium 1UniRule annotation1
Metal bindingi69Magnesium 1UniRule annotation1
Metal bindingi133Magnesium 2UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease HUniRule annotationSAAS annotation (EC:3.1.26.4UniRule annotationSAAS annotation)
Short name:
RNase HUniRule annotation
Gene namesi
Name:rnhAUniRule annotation
ORF Names:AGRO_0070Imported
OrganismiAgrobacterium sp. ATCC 31749Imported
Taxonomic identifieri82789 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacterium
Proteomesi
  • UP000003574 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliF5J4M0
SMRiF5J4M0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 141RNase HInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the RNase H family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiPOG091H04XT

Family and domain databases

CDDicd09278 RNase_HI_prokaryote_like, 1 hit
Gene3Di3.30.420.10, 1 hit
HAMAPiMF_00042 RNase_H, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
IPR022892 RNaseHI
PfamiView protein in Pfam
PF00075 RNase_H, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit

Sequencei

Sequence statusi: Complete.

F5J4M0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKHVDIFTDG ACSGNPGPGG WGAVLRYGET EKELSGGEAD TTNNRMELLA
60 70 80 90 100
AISALNALKS PCEVDLYTDS AYVKDGITKW IFGWKKKGWK TADNKPVKNV
110 120 130 140
ELWQALEAAQ ERHKVTLHWV KGHAGHPENE RADELARKGM EPFKRR
Length:146
Mass (Da):16,261
Last modified:July 27, 2011 - v1
Checksum:iCA90796A79057155
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AECL01000001 Genomic DNA Translation: EGL67224.1
RefSeqiWP_003511799.1, NZ_AECL01000001.1

Genome annotation databases

EnsemblBacteriaiEGL67224; EGL67224; AGRO_0070
GeneIDi31900165

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AECL01000001 Genomic DNA Translation: EGL67224.1
RefSeqiWP_003511799.1, NZ_AECL01000001.1

3D structure databases

ProteinModelPortaliF5J4M0
SMRiF5J4M0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEGL67224; EGL67224; AGRO_0070
GeneIDi31900165

Phylogenomic databases

OrthoDBiPOG091H04XT

Family and domain databases

CDDicd09278 RNase_HI_prokaryote_like, 1 hit
Gene3Di3.30.420.10, 1 hit
HAMAPiMF_00042 RNase_H, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
IPR022892 RNaseHI
PfamiView protein in Pfam
PF00075 RNase_H, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5J4M0_9RHIZ
AccessioniPrimary (citable) accession number: F5J4M0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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