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Protein

Membrane protein US21

Gene

US21

Organism
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein US21
Gene namesi
Name:US21
OrganismiHuman cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Taxonomic identifieri295027 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000938 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 40HelicalSequence analysisAdd BLAST21
Transmembranei47 – 67HelicalSequence analysisAdd BLAST21
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Transmembranei106 – 126HelicalSequence analysisAdd BLAST21
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004183231 – 243Membrane protein US21Add BLAST243

Proteomic databases

PRIDEiF5HHT6

Structurei

3D structure databases

ProteinModelPortaliF5HHT6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytomegalovirus US12 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000QP

Family and domain databases

InterProiView protein in InterPro
IPR006214 Bax_inhibitor_1-related
PANTHERiPTHR23291 PTHR23291, 1 hit
PfamiView protein in Pfam
PF01027 Bax1-I, 1 hit

Sequencei

Sequence statusi: Complete.

F5HHT6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLRGQVQIA RSVFLLRIYI LIWVQCLILM SVCAFCWLVL PHRLEQLFSS
60 70 80 90 100
VRLTLSCLMI SIVCLGLLRW AEPNFPKNVW ILLTYTLLTS VAVTASGFHF
110 120 130 140 150
SHRSVIYAMV ATVTLFCFLT LATYLFARDV ELQRSLLTGA STLILLLFAV
160 170 180 190 200
FSLFPEAVSE ILVMIAGLAV IVTSVVCDTQ DILHDIEYES YIPGALCLYM
210 220 230 240
DLMYLFVSVL YFMPSEPGSA HTAQTTVAAT VAATAAASPQ FVS
Length:243
Mass (Da):26,927
Last modified:June 28, 2011 - v1
Checksum:i756CF7CE0E2B7334
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY446894 Genomic DNA Translation: AAR31710.1
RefSeqiYP_081606.1, NC_006273.2

Genome annotation databases

GeneIDi3077437
KEGGivg:3077437

Similar proteinsi

Entry informationi

Entry nameiUS21_HCMVM
AccessioniPrimary (citable) accession number: F5HHT6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2012
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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